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Table 2 Clinical characteristics

From: Sarcopenic obesity and its association with frailty and protein-energy wasting in hemodialysis patients: preliminary data from a single center in Japan

 

Normal (n = 46)

Obese (n = 18)

Sarcopenia (n = 35)

Sarcopenic obesity (n = 18)

p value

Age, years

60 ± 12

62 ± 12

70 ± 12 †

67 ± 9

0.002

Female, n (%)

11 (24)

8 (44)

12 (34)

10 (56)

0.088

BMI, kg/m2

23.6 ± 3.5

27.1 ± 5.8 †

20.8 ± 2.8 †

26.3 ± 4.6 †§

< 0.001

HD vintage, years

7 ± 5

8 ± 5

7 ± 7

5 ± 5

0.535

Comorbidity

Hypertension, n (%)

45 (98%)

18 (100%)

33 (94%)

15 (83%)

0.080

Dyslipidemia, n (%)

15 (33%)

3 (17%)

8 (24%)

6 (33%)

0.525

Diabetes mellitus, n (%)

24 (52%)

11 (61%)

16 (46%)

14 (78%)

0.144

Laboratory data

Hb, g/dL

10.5 ± 1.1

10.4 ± 1.1

10.4 ± 1.4

10.6 ± 1.0

0.921

sCr, mg/dL

11.7 ± 2.7

11.9 ± 2.2

9.9 ± 2.5 †‡

9.5 ± 2.5 †‡

0.001

BUN, g/dL

63.2 ± 15.5

62.4 ± 14.8

55.8 ± 17.8

58.8 ± 14.6

0.209

Alb, mg/dL

3.7 ± 0.3

3.8 ± 0.3

3.6 ± 0.3

3.7 ± 0.3

0.093

P, pg/dL

5.8 ± 1.3

5.8 ± 1.2

5.4 ± 1.2

5.5 ± 1.6

0.497

Ca, mg/dL

8.9 ± 0.7

8.8 ± 0.9

8.7 ± 0.7

8.8 ± 0.8

0.721

K, mg/dL

4.9 ± 0.8

5.1 ± 0.5

4.8 ± 0.7

5.1 ± 0.7

0.425

CRP, mg/dL

0.5 ± 1.2

0.3 ± 0.3

0.4 ± 0.7

0.9 ± 2.3

0.463

KT/V

1.3 ± 0.2

1.4 ± 0.2

1.3 ± 0.3

1.3 ± 0.3

0.809

nPNA, g/kg/day

0.9 ± 0.2

0.9 ± 0.2

0.8 ± 0.2

0.8 ± 0.2

0.558

MNA-SF, points

12.5 ± 1.9

13.2 ± 1.3

11.6 ± 1.7 ‡

12.6 ± 1.8

0.008

EAT-10, points

1.3 ± 3.6

0.4 ± 1.1

1.5 ± 4.1

0.6 ± 1.4

0.619

SNAQ, points

14.6 ± 2.7

14.7 ± 1.7

14.4 ± 2.5

15.1 ± 1.3

0.795

% Fat mass, %

18.8 ± 8.5

37.8 ± 5.3 †

22.2 ± 4.7 ‡

38.1 ± 5.9 †§

< 0.001

Skeletal muscle mass index, kg/m2

7.6 ± 5.1

4.0 ± 1.2 †

3.3 ± 0.9 †

3.2 ± 0.7 †

< 0.001

Muscle wasting, n (%)

26 (68%)

17 (94%)

35 (100%)

18 (100%)

< 0.001

  1. BMI body mass index, HD hemodialysis, Hb hemoglobin, sCr serum creatinine, BUN blood urine nitrogen, Alb albumin, P phosphorus, Ca calcium, K potassium, CRP C-reactive protein, KT/V K-dialyzer clearance of urea, t dialysis time, V volume of distribution of urea, nPNA normalized protein nitrogen appearance, MNA-SF Mini Nutritional Assessment short form, SNAQ Simplified Nutritional Appetite Questionnaire
  2. †p < 0.05 vs. the normal group, and ‡p < 0.05 vs. the obese group