Skip to main content

Table 1 Kidney diseases that are identified in HIV-infected patients

From: A high likelihood of increase in end-stage renal disease among the Japanese HIV-infected population

Diseases

Clinical characteristics

HIV-specific glomerular disease

 HIVAN

Detectable viral load, a high amount of proteinuria, albuminuria, RPGN

 HIVIC

Proteinuria and/or hematuria, variable manifestation including AKI

 TMA

AKI, proteinuria, hematuria with microangiopathic hemolytic anemia and thrombocytopenia

HIV-non-specific glomerular disease

 HCV-related glomerulonephritis

Proteinuria and/or hematuria, nephritic syndrome, a decrease in serum complements

 Diabetic nephropathy

Proteinuria (microalbuminuria to nephrotic syndrome), a decrease in GFR

 Glomerular sclerosis

Older patients, hypertension, no or low amount of proteinuria, coexistence of atherosclerotic diseases

 Membranous glomerulopathy

Nephrotic syndrome; idiopathic and secondary causes associated with HBV or cancers

 Minimal change disease

Nephrotic syndrome, use of NSAIDs

 IgA nephropathy

Hematuria and/or proteinuria with or without renal failure

 Post-infectious glomerulonephritis

Hematuria and/or proteinuria with or without renal failure

ART-associated tubular injury

 Acute tubular necrosis

Use of TDF

 Cristal nephropathy

Use of IDV and ATV

 Acute or chronic interstitial nephritis

Use of ATV

  1. HIVAN HIV-associated nephropathy, HIVIC HIV-associated immune complex kidney disease, TMA thrombotic microangiopathy, HCV hepatitis C virus, HBV hepatitis B virus, AKI acute kidney injury, GFR glomerular filtration rate, NSAID non-steroidal anti-inflammatory drug, ART antiretroviral therapy, TDF tenofovir disoproxil fumarate, IDV indinavir, ATV atazanavir