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Table 1 Characteristics of the included studies

From: Topical application of mupirocin to exit sites in patients on peritoneal dialysis: a systematic review and meta-analysis of randomized controlled trials

StudyDesign follow-upParticipantsInclusionExclusionInterventionsOutcomesNotes
Wong et al. [34]RCT 5 monthsCountries, Hong Kong; setting, single centerBoth incident and prevalent PD patientsPsychiatric, dermatological, or terminal illness; presence of peritonitis or ESI; the use of antibiotics within a monthMupirocin, n = 73; control, n = 81; dropout, n = 12ESI, peritonitis, technical failureFunding source was not stated.
Olga et al. [16]RCT 86.7 patient-years for M, 60.4 patient-years for CCountries, Greece; setting, single centerBoth incident and prevalent PD patientsPeritonitis or ESI within 3 monthsMupirocin, n = 33; control, n = 29ESI, peritonitis, technical failureFunding source was not stated.
Findaly et al. [18]RCT 58.1 patient-years for M, 53.9 patient-years for CCountries, United Kingdom; setting, not statedBoth incident and prevalent PD patientsPeritonitis or ESI within a monthMupirocin, n = 53; control, n = 53ESI, peritonitis, technical failureFunding source was not stated.
Bernadini et al. [19]RCT 53.8 patient-years for M, 64.3 patient-years for GCountries, United States; setting, multicenterBoth incident and prevalent PD patients enrolled in a registry at three centers.Allergy to mupirocin or gentamicin, peritonitis or ESI within a monthMupirocin, n = 66; gentamicin, n = 67ESI, peritonitis, technical failureThis study was supported by the National Kidney Foundation of Western Pennsylvania, National Kidney Foundation of Upstate New York, and the Paul Teschan Fund of Dialysis Clinic, Inc.
Chu et al. [9]RCT 44.9 patient-years for M, 39.6 patient-years for GCountries, Hong Kong; setting, single centerBoth incident and prevalent PD patientsAllergy to mupirocin or gentamicin, peritonitis or ESI within 4 weeks, active infectionMupirocin n = 38; gentamicin, n = 43; dropout, n = 14ESI, peritonitis, technical failureFunding source was not stated.
Mortazavi et al. [17]RCT 29.8 patient-years for M, 29.4 patient-years for GCountries, Iran; setting, single center Use of antibiotics within a month, allergy to mupirocin or gentamicinMupirocin, n = 61; gentamicin, n = 60; dropout, n = 10Peritonitis, technical failureFunding source was not stated.
  1. RCT randomized controlled trial, PD peritoneal dialysis, ESI exit site infection, C control, M application of mupirocin ointment to exit site, G application of gentamicin ointment on the exit site