Skip to main content

Table 3 Summary of findings

From: Topical application of mupirocin to exit sites in patients on peritoneal dialysis: a systematic review and meta-analysis of randomized controlled trials

Outcomes

Illustrative comparative risk (event/100 patient-years) (95% CI)

Rate ratio (95% CI)

No. of participants (studies)

Quality of the evidence (GRADE)

Control or gentamicin

Mupirocin

Comparison between the mupirocin ointment group and control group

Exit-site infection

27.7

10.0 (3.6–29.1)

0.36 (0.13–1.05)

322 (3 studies)

Very low*1

Peritonitis

29.7

23.2 (14.9–35.9)

0.78 (0.50–1.21)

322 (3 studies)

*2

Low

Technical failure

2.0

2.7 (0.5–14.4)

1.35 (0.25–7.21)

322 (3 studies)

*3

Low

Comparison between the mupirocin ointment group and the gentamicin ointment group

Exit-site infection

28.9

32.9 (7.8–138.8)

1.14 (0.27–4.81)

214 (2 studies)

*4

Very low

Peritonitis

32.3

27.4 (10.3–72.9)

0.85 (0.32–2.26)

335 (3 studies)

*5

Low

Technical failure

16.5

9.6 (4.6–19.8)

0.58 (0.28–1.20)

214 (3 studies)

*6

Low

  1. *1Serious unexplained heterogeneity, based on studies with high risk of bias
  2. *2Based on studies with high risk of bias
  3. *3Increased risk of bias related to incomplete outcome data and selective reporting, based on studies with high risk of bias
  4. *4Increased risk of bias related to incomplete outcome data and selective reporting, based on studies with high risk of bias, serious unexplained heterogeneity
  5. *5Increased risk of bias related to incomplete outcome data and selective reporting, based on studies with high risk of bias, serious unexplained heterogeneity
  6. *6Increased risk of bias related to incomplete outcome data and selective reporting, based on studies with high risk of bias