Parameter | Mean ± SD | p value | |
---|---|---|---|
Baseline | Week 12 after administration | ||
Total CSS score | 10.4 ± 3.2 | 5.7 ± 3.2 | < 0.001 |
Stool frequency | 0.9 ± 0.7 | 0.4 ± 0.6 | 0.005 |
Dyschezia | 1.9 ± 0.9 | 0.6 ± 0.8 | < 0.001 |
A sensation of incomplete evacuation | 2.2 ± 1.3 | 1.3 ± 1.4 | 0.028 |
Abdominal pain | 1.2 ± 1.1 | 0.5 ± 1.0 | 0.031 |
Time to evacuation | 0.9 ± 0.7 | 0.6 ± 0.8 | 0.145 |
Assisted bowel movements | 1.2 ± 0.4 | 0.8 ± 0.4 | 0.020 |
Number of bowel movements failed/24 h | 1.1 ± 0.5 | 0.3 ± 0.5 | < 0.001 |
Duration (years) of suffering from disturbed defecation | 1.1 ± 0.9 | 1.3 ± 1.1 | ― |