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Table 3 Comparison of spontaneous stool frequency and constipation score by clinical history

From: Efficacy and safety of elobixibat in hemodialysis patients with chronic constipation: a retrospective study

ParameterCurrent medical historyMean ± SDp value
BaselineWeek 12 after administration
Spontaneous stool frequencyDiabetic nephropathy1.8 ± 0.54.9 ± 2.40.009
Others2.2 ± 0.95.0 ± 2.4< 0.001
Total CSS scoreDiabetic nephropathy10.6 ± 3.66.8 ± 4.30.014
Others10.3 ± 2.95.0 ± 2.10.006
Stool frequencyDiabetic nephropathy1.1 ± 0.40.3 ± 0.50.011
Others0.8 ± 0.90.5 ± 0.70.203
DyscheziaDiabetic nephropathy1.5 ± 0.80.9 ± 1.00.120
Others2.2 ± 1.00.4 ± 0.70.003
A sensation of incomplete evacuationDiabetic nephropathy2.4 ± 1.31.6 ± 1.60.095
Others2.0 ± 1.31.1 ± 1.20.138
Abdominal painDiabetic nephropathy1.4 ± 0.70.8 ± 1.40.284
Others1.0 ± 1.30.3 ± 0.60.048
Time to evacuationDiabetic nephropathy1.1 ± 0.80.8 ± 0.90.149
Others0.7 ± 0.60.5 ± 0.70.530
Assisted bowel movementsDiabetic nephropathy1.0 ± 0.01.0 ± 0.0
Others1.3 ± 0.50.7 ± 0.50.020
Number of bowel movements failed/24 hDiabetic nephropathy1.0 ± 0.50.4 ± 0.50.037
Others1.2 ± 0.40.2 ± 0.40.003
Duration (years) of suffering from disturbed defecationDiabetic nephropathy1.1 ± 0.61.1 ± 0.6
Others1.1 ± 1.01.4 ± 1.4
  1. Results of analysis: diabetic nephropathy n = 8, others n = 11
  2. Statistical analysis was performed using the paired t-test (spontaneous stool frequency) or Wilcoxon signed-rank test (CSS scores)
  3. No statistical analysis was performed on the duration of suffering from disturbed defecation
  4. †The p value could not be calculated