Table 4 Comparison of spontaneous stool frequency and constipation score by the use of phosphate binder
Parameter | Use of phosphate binder | Mean ± SD | p value | |
|---|---|---|---|---|
Baseline | Week 12 after administration | |||
Spontaneous stool frequency | Yes | 1.8 ± 0.6 | 4.9 ± 2.3 | < 0.001 |
No | 2.6 ± 0.9 | 5.2 ± 2.6 | 0.033 | |
Total CSS score | Yes | 10.1 ± 3.1 | 5.7 ± 2.7 | 0.002 |
No | 11.2 ± 3.5 | 5.8 ± 4.8 | 0.058 | |
Stool frequency | Yes | 0.8 ± 0.6 | 0.4 ± 0.6 | 0.041 |
No | 1.4 ± 0.9 | 0.4 ± 0.5 | 0.089 | |
Dyschezia | Yes | 1.8 ± 1.0 | 0.5 ± 0.7 | 0.002 |
No | 2.2 ± 0.8 | 0.8 ± 1.3 | 0.134 | |
A sensation of incomplete evacuation | Yes | 2.2 ± 1.3 | 1.3 ± 1.4 | 0.091 |
No | 2.0 ± 1.2 | 1.4 ± 1.5 | 0.149 | |
Abdominal pain | Yes | 1.3 ± 1.1 | 0.6 ± 1.2 | 0.101 |
No | 0.8 ± 0.8 | 0.2 ± 0.4 | 0.149 | |
Time to evacuation | Yes | 0.9 ± 0.8 | 0.6 ± 0.6 | 0.182 |
No | 1.0 ± 0.7 | 0.8 ± 1.1 | 0.773 | |
Assisted bowel movements | Yes | 1.1 ± 0.4 | 0.9 ± 0.3 | 0.149 |
No | 1.2 ± 0.4 | 0.6 ± 0.5 | 0.149 | |
Number of bowel movements failed/24 h | Yes | 1.1 ± 0.5 | 0.3 ± 0.5 | 0.002 |
No | 1.0 ± 0.0 | 0.2 ± 0.4 | 0.072 | |
Duration (years) of suffering from disturbed defecation | Yes | 0.9 ± 0.5 | 1.2 ± 1.0 | ― |
No | 1.6 ± 1.5 | 1.4 ± 1.7 | ― | |