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Table 4 Comparison of spontaneous stool frequency and constipation score by the use of phosphate binder

From: Efficacy and safety of elobixibat in hemodialysis patients with chronic constipation: a retrospective study

ParameterUse of phosphate binderMean ± SDp value
BaselineWeek 12 after administration
Spontaneous stool frequencyYes1.8 ± 0.64.9 ± 2.3< 0.001
No2.6 ± 0.95.2 ± 2.60.033
Total CSS scoreYes10.1 ± 3.15.7 ± 2.70.002
No11.2 ± 3.55.8 ± 4.80.058
Stool frequencyYes0.8 ± 0.60.4 ± 0.60.041
No1.4 ± 0.90.4 ± 0.50.089
DyscheziaYes1.8 ± 1.00.5 ± 0.70.002
No2.2 ± 0.80.8 ± 1.30.134
A sensation of incomplete evacuationYes2.2 ± 1.31.3 ± 1.40.091
No2.0 ± 1.21.4 ± 1.50.149
Abdominal painYes1.3 ± 1.10.6 ± 1.20.101
No0.8 ± 0.80.2 ± 0.40.149
Time to evacuationYes0.9 ± 0.80.6 ± 0.60.182
No1.0 ± 0.70.8 ± 1.10.773
Assisted bowel movementsYes1.1 ± 0.40.9 ± 0.30.149
No1.2 ± 0.40.6 ± 0.50.149
Number of bowel movements failed/24 hYes1.1 ± 0.50.3 ± 0.50.002
No1.0 ± 0.00.2 ± 0.40.072
Duration (years) of suffering from disturbed defecationYes0.9 ± 0.51.2 ± 1.0
No1.6 ± 1.51.4 ± 1.7
  1. Results of analysis: patients with phosphate binder treatment n = 14, patients without phosphate binder treatment n = 5
  2. Statistical analysis was performed using the paired t-test (spontaneous stool frequency) or Wilcoxon signed-rank test (CSS scores)
  3. No statistical analysis was performed on the duration of suffering from disturbed defecation