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Table 1 Characteristics of the included studies

From: The impact of intraperitoneal antibiotic administration in patients with peritoneal dialysis-related peritonitis: systematic review and meta-analysis

LiteratureResearch designParticipantsInterventionControlOutcomes
Bailie et al. Nephron 1987 46 316RCT20 patients with PD-related peritonitis, (GPC-positive) 1 hospital, the UKIP administration, VCM 1 g, as initial therapyIV administration, VCM 1 g, as initial therapyNo difference in serum VCM levels
3 cases of route-related complication
Bennett-Jones et al. J Antimicrob Chemother 1990 26 73RCT93 patients with PD-related peritonitis, 1 hospital, the UKIP administration, VCM 20 mg/L and TOB 4 mg/LIV administration, VCM 0.5 or 1.0 g, TOB 1.0 mg/kgSuccess in therapy, 35 of 39 cases (89.1%) vs. 23 of 36 cases (65.9%) (p < 0.02)
  1. RCT randomized controlled trial, PD peritoneal dialysis, IP intraperitoneal, IV intravenous, VCM vancomycin, TOB tobramycin