Table 1 Characteristics of the included studies
Literature | Research design | Participants | Intervention | Control | Outcomes |
|---|---|---|---|---|---|
Bailie et al. Nephron 1987 46 316 | RCT | 20 patients with PD-related peritonitis, (GPC-positive) 1 hospital, the UK | IP administration, VCM 1 g, as initial therapy | IV administration, VCM 1 g, as initial therapy | No difference in serum VCM levels 3 cases of route-related complication |
Bennett-Jones et al. J Antimicrob Chemother 1990 26 73 | RCT | 93 patients with PD-related peritonitis, 1 hospital, the UK | IP administration, VCM 20 mg/L and TOB 4 mg/L | IV administration, VCM 0.5 or 1.0 g, TOB 1.0 mg/kg | Success in therapy, 35 of 39 cases (89.1%) vs. 23 of 36 cases (65.9%) (p < 0.02) |