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Table 1 Laboratory data of the patient on admission

From: Pembrolizumab-associated thrombotic microangiopathy in a patient with urothelial cancer: a case report and literature review

Blood biochemistry

 

Blood count

 

 TP, g/dL

5.6

 WBC, /μL

15,100

 Alb, g/dL

3.1

 Seg, %

95

 Na, mmol/L

137

 Lymp, %

1.0

 K, mmol/L

5.5

 Hb, g/dL

8.0

 CL, mmol/L

112

 Schistocytes

Positive

 Ca, mg/dL

7.1

Reticulocytes, %

13

 IP, mg/dL

9.0

 Plt, × 10^4/μL

3.5

 BUN, mg/dL

101

  

 Cre, mg/dL

13.4

  

 T-Bil, mg/dL

1.8

Coagulation

 

 D-Bil, mg/dL

0.8

 PT-INR

1.48

 AST, U/L

72

 APTT, %

44

 ALT, U/L

22

 Fibrinogen

256

 LD, U/L

1156

 FDP, μg/ml

42.9

 γ-GTP, U/L

48

 D-dimer, μg/mL

21.5

 ALP, U/L

224

 TAT, ng/mL

53.5

 Amy, U/L

175

 PIC, μg/mL

0.8

 CK, U/L

296

 Antithrombin III, %

115

 CRP, mg/dL

17

  

 PCT, ng/mL

1.73

  

 BNP, pg/mL

513

  

 IgG, mg/dL

983

Arterial blood gas

 

 IgA, mg/dL

124

(O2 2L/min through nasal cannula)

 IgM, mg/dL

98

 pH

7.41

 C3, mg/dL

85

 PaCO2, mmHg

17.9

 C4, mg/dL

27

 PaO2, mmHg

151.2

 CH50, U/mL

60

 HCO3, mmol/L

11

 ADAMTS13, %

38

 BE, mmol/L

− 12

 ADAMTS13 inhibitor

Negative

 Glu, mg/dL

111

 Haptoglobin, mg/dL

3

 Lac, mmol/L

1.31

  1. TP total protein, Alb albumin, Na sodium, K potassium, CL chloride, Ca calcium, IP inorganic phosphorus, BUN blood urine nitrogen, Cre creatinine, T-Bil total bilirubin, D-Bil direct bilirubin, AST aspartate aminotransferase, ALT alanine aminotransferase, LD lactate dehydrogenase, γ-GTP γ-glutamyl transpeptidase, ALP alkaline phosphatase, Amy amylase, CK creatinine kinase, CRP C-reactive protein, PCT procalcitonin, BNP brain natriuretic peptide, Ig immunoglobulin, C3 complement component 3, C4 complement component 4, CH50 50% hemolytic complement activity, ADAMTS13 a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13, WBC white blood cell, Neut neutrophil, Lymp lymphocyte, Hb hemoglobin, Plt platelet, PT-INR prothrombin time-international normalized ratio, APTT activated partial thromboplastin time, FDP fibrin degradation product, TAT thrombin antithrombin complex, PIC plasmin α2-plasmin inhibitor complex, PaCO2 partial pressure of carbon dioxide, PaO2 partial pressure of oxygen, HCO3 bicarbonate, BE base excess, Glu glucose, Lac lactate