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Table 1 Laboratory data of the patient on admission

From: Pembrolizumab-associated thrombotic microangiopathy in a patient with urothelial cancer: a case report and literature review

Blood biochemistry   Blood count  
 TP, g/dL 5.6  WBC, /μL 15,100
 Alb, g/dL 3.1  Seg, % 95
 Na, mmol/L 137  Lymp, % 1.0
 K, mmol/L 5.5  Hb, g/dL 8.0
 CL, mmol/L 112  Schistocytes Positive
 Ca, mg/dL 7.1 Reticulocytes, % 13
 IP, mg/dL 9.0  Plt, × 10^4/μL 3.5
 BUN, mg/dL 101   
 Cre, mg/dL 13.4   
 T-Bil, mg/dL 1.8 Coagulation  
 D-Bil, mg/dL 0.8  PT-INR 1.48
 AST, U/L 72  APTT, % 44
 ALT, U/L 22  Fibrinogen 256
 LD, U/L 1156  FDP, μg/ml 42.9
 γ-GTP, U/L 48  D-dimer, μg/mL 21.5
 ALP, U/L 224  TAT, ng/mL 53.5
 Amy, U/L 175  PIC, μg/mL 0.8
 CK, U/L 296  Antithrombin III, % 115
 CRP, mg/dL 17   
 PCT, ng/mL 1.73   
 BNP, pg/mL 513   
 IgG, mg/dL 983 Arterial blood gas  
 IgA, mg/dL 124 (O2 2L/min through nasal cannula)
 IgM, mg/dL 98  pH 7.41
 C3, mg/dL 85  PaCO2, mmHg 17.9
 C4, mg/dL 27  PaO2, mmHg 151.2
 CH50, U/mL 60  HCO3, mmol/L 11
 ADAMTS13, % 38  BE, mmol/L − 12
 ADAMTS13 inhibitor Negative  Glu, mg/dL 111
 Haptoglobin, mg/dL 3  Lac, mmol/L 1.31
  1. TP total protein, Alb albumin, Na sodium, K potassium, CL chloride, Ca calcium, IP inorganic phosphorus, BUN blood urine nitrogen, Cre creatinine, T-Bil total bilirubin, D-Bil direct bilirubin, AST aspartate aminotransferase, ALT alanine aminotransferase, LD lactate dehydrogenase, γ-GTP γ-glutamyl transpeptidase, ALP alkaline phosphatase, Amy amylase, CK creatinine kinase, CRP C-reactive protein, PCT procalcitonin, BNP brain natriuretic peptide, Ig immunoglobulin, C3 complement component 3, C4 complement component 4, CH50 50% hemolytic complement activity, ADAMTS13 a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13, WBC white blood cell, Neut neutrophil, Lymp lymphocyte, Hb hemoglobin, Plt platelet, PT-INR prothrombin time-international normalized ratio, APTT activated partial thromboplastin time, FDP fibrin degradation product, TAT thrombin antithrombin complex, PIC plasmin α2-plasmin inhibitor complex, PaCO2 partial pressure of carbon dioxide, PaO2 partial pressure of oxygen, HCO3 bicarbonate, BE base excess, Glu glucose, Lac lactate