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Table 5 Cox’s proportional hazard ratio of prognostic correcting factors

From: Range of plasma brain natriuretic peptide (BNP) levels in hemodialysis patients at a high risk of 1-year mortality and their relationship with the nutritional status: a retrospective cohort study in one institute

factor Hazard ratio 95%CI p value
lower upper
Basal correcting factors
Gender
  male (reference) 1    
  female 0.8071195 0.482928 1.301835 0.3874
Age
  per year 1.080624 1.056946 1.105951 0.925391
Hemodialysis vintage(year)
  <2 1.2368068 0.676626 2.236559 0.4845
  2~ 0.9264575 0.511665 1.664664 0.7981
  5~ (reference) 1    
  10~ 0.6188481 0.246238 1.363282 0.2444
  15~ 0.835351 0.245519 2.161668 0.7336
  20~ 0.8217469 0.045988 3.884436 08428
  25~ 6.6119647 0.369841 31.30687 0.1522
  30~ - - - -
Primary disease
  CGN (reference) 1    
  DN 2.1136519 1.317961 3.452752 0.0018
  others 0.9470856 0.379865 2.057472 0.8975
Hemodialysis prescription factor
Single pool Kt/V
  <0.8 3.4472538 1.113841 9.013165 0.0336
  0.8 to <1.0 1.3144702 0.303081 4.027443 0.6766
  1.0 to <1.2 2.4205658 1.123396 5.178495 0.0246
  1.2 to <1.4 (reference) 1    
  1.4 to <1.6 0.9066037 0.472084 1.805214 0.7733
  1.6 to <1.8 0.6185594 0.281182 1.339853 0.2214
  1.8 to <2.0 0.4126628 0.116978 1.150472 0.0935
  2.0 0.7575922 0.214755 2.1121 0.6157
Nutrition relating factors
nPCR (g/kg/day)
  <0.5 3.5341434 1.326819 791195  0.0144
  0.5 to <0.7 2.0793417 1.267456 3.424633  0.0039
  0.7 to <0.9 (reference) 1    
  0.9 to <1.1 0.6749971 0.288367 1.402628 0.3057
  1.1 to <1.3 2.11E-09 0 1.180454 0.0706
  1.3 2.11E-09 0 10.03386 0.5302
Albumin (g/dl)
  <0.3 8.9979761 4.666076 17.49091 <.0001
  3.0 to <3.5 3.2500965 1.875694 5.882808 <.0001
  3.5 to <4.0 (reference) 1    
  4.0 to <4.5 0.5191474 0.0082335 1.810644 0.3393
  4.5 3.22E-08 0 35.6988 0.7359
Total cholesterol (mg/dl)
  <80 - - - -
  80 to <120 1.3127943 0.637005  2.493205 0.441
  120 to <160 (reference) 1    
  160 to <200 0.7676479 0.431736 1.321843 0.3451
  200 to <240 0.7481263 0.180457 2.071826 0.6148
  240 77.12728 4.101126 441.142 0.0104
BMI (kg/m2)
  <16 2.6829842 0.593253 12.33062  0.1361
  16 to <18 1.4307039 0.532743 3.250588  0.4465
  18 to <20 0.764411 0.380715 1.460268  0.4227
20 to <22 (reference) 1    
  22 to <24 0.7607745 0.405455 1.390405 0.3769
  24 to <26 0.6119119 0.258927 1.292297 0.206
  26 to <28 0.2169053 0.012157 1.01973 0.0538
  28 0.7508242 0.221565 1.927202 0.5806
%CGR (%)
  <60 3.5766971 1.630619 8.3974 0.0014
  60 to <70 2.7486736 1.107819 6.919564 0.0297
  70 to <80 1.4473888 0.56513 3.706997 0.4341
  80 to <90 1.4485841 0.599571 3.593324 0.4081
  90 to <100 (reference) 1    
  100 to <110 1.166507 0.482823 2.893589 0.7313
  110 to <120 0.508935 0.112931 1.705797 0.287
  120 to <130 0.6324356 0.096427 2.454098 0.5391
  130 1.059352 0.235067 3.550648 0.9314
Transthyretin (mg/dl)
<15 10.055064 4.997492 20.87464 <.0001
15 to <20 3.8640013 1.924016 8.008218 0.0002
20 to <25 (reference) 1    
25 to <30 1.089919 0.509545 2.348036 0.823
30 to <35 0.759041 0.313215 1.759291 0.5221
35 to <40 0.350335 0.080339 1.086928 0.0712
40 5.23E-10 0 0.368802 0.0023
  1. BMI body mass index, CGN chronic glomerulonephritis, DN diabetic nephropathy, nPCR normalized protein catabolic rate, %CGR percent creatinine generation rate