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Table 5 Cox’s proportional hazard ratio of prognostic correcting factors

From: Range of plasma brain natriuretic peptide (BNP) levels in hemodialysis patients at a high risk of 1-year mortality and their relationship with the nutritional status: a retrospective cohort study in one institute

factor

Hazard ratio

95%CI

p value

lower

upper

Basal correcting factors

Gender

  male (reference)

1

   

  female

0.8071195

0.482928

1.301835

0.3874

Age

  per year

1.080624

1.056946

1.105951

0.925391

Hemodialysis vintage(year)

  <2

1.2368068

0.676626

2.236559

0.4845

  2~

0.9264575

0.511665

1.664664

0.7981

  5~ (reference)

1

   

  10~

0.6188481

0.246238

1.363282

0.2444

  15~

0.835351

0.245519

2.161668

0.7336

  20~

0.8217469

0.045988

3.884436

08428

  25~

6.6119647

0.369841

31.30687

0.1522

  30~

-

-

-

-

Primary disease

  CGN (reference)

1

   

  DN

2.1136519

1.317961

3.452752

0.0018

  others

0.9470856

0.379865

2.057472

0.8975

Hemodialysis prescription factor

Single pool Kt/V

  <0.8

3.4472538

1.113841

9.013165

0.0336

  0.8 to <1.0

1.3144702

0.303081

4.027443

0.6766

  1.0 to <1.2

2.4205658

1.123396

5.178495

0.0246

  1.2 to <1.4 (reference)

1

   

  1.4 to <1.6

0.9066037

0.472084

1.805214

0.7733

  1.6 to <1.8

0.6185594

0.281182

1.339853

0.2214

  1.8 to <2.0

0.4126628

0.116978

1.150472

0.0935

  2.0

0.7575922

0.214755

2.1121

0.6157

Nutrition relating factors

nPCR (g/kg/day)

  <0.5

3.5341434

1.326819

791195

 0.0144

  0.5 to <0.7

2.0793417

1.267456

3.424633

 0.0039

  0.7 to <0.9 (reference)

1

   

  0.9 to <1.1

0.6749971

0.288367

1.402628

0.3057

  1.1 to <1.3

2.11E-09

0

1.180454

0.0706

  1.3

2.11E-09

0

10.03386

0.5302

Albumin (g/dl)

  <0.3

8.9979761

4.666076

17.49091

<.0001

  3.0 to <3.5

3.2500965

1.875694

5.882808

<.0001

  3.5 to <4.0 (reference)

1

   

  4.0 to <4.5

0.5191474

0.0082335

1.810644

0.3393

  4.5

3.22E-08

0

35.6988

0.7359

Total cholesterol (mg/dl)

  <80

-

-

-

-

  80 to <120

1.3127943

0.637005

 2.493205

0.441

  120 to <160 (reference)

1

   

  160 to <200

0.7676479

0.431736

1.321843

0.3451

  200 to <240

0.7481263

0.180457

2.071826

0.6148

  240

77.12728

4.101126

441.142

0.0104

BMI (kg/m2)

  <16

2.6829842

0.593253

12.33062

 0.1361

  16 to <18

1.4307039

0.532743

3.250588

 0.4465

  18 to <20

0.764411

0.380715

1.460268

 0.4227

20 to <22 (reference)

1

   

  22 to <24

0.7607745

0.405455

1.390405

0.3769

  24 to <26

0.6119119

0.258927

1.292297

0.206

  26 to <28

0.2169053

0.012157

1.01973

0.0538

  28

0.7508242

0.221565

1.927202

0.5806

%CGR (%)

  <60

3.5766971

1.630619

8.3974

0.0014

  60 to <70

2.7486736

1.107819

6.919564

0.0297

  70 to <80

1.4473888

0.56513

3.706997

0.4341

  80 to <90

1.4485841

0.599571

3.593324

0.4081

  90 to <100 (reference)

1

   

  100 to <110

1.166507

0.482823

2.893589

0.7313

  110 to <120

0.508935

0.112931

1.705797

0.287

  120 to <130

0.6324356

0.096427

2.454098

0.5391

  130

1.059352

0.235067

3.550648

0.9314

Transthyretin (mg/dl)

<15

10.055064

4.997492

20.87464

<.0001

15 to <20

3.8640013

1.924016

8.008218

0.0002

20 to <25 (reference)

1

   

25 to <30

1.089919

0.509545

2.348036

0.823

30 to <35

0.759041

0.313215

1.759291

0.5221

35 to <40

0.350335

0.080339

1.086928

0.0712

40

5.23E-10

0

0.368802

0.0023

  1. BMI body mass index, CGN chronic glomerulonephritis, DN diabetic nephropathy, nPCR normalized protein catabolic rate, %CGR percent creatinine generation rate