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Table 2 Inflammatory and immunological data changes before and after CRRT

From: Effects of continuous renal replacement therapy with the AN69ST membrane for septic shock and sepsis-induced AKI in an infant: a case report with literature review of cytokine/mediator removal therapy in children

  

Before

During CRRT

12 h after discontinuing CRRT

Parameter

Normal value

12 h

24 h

48 h

72 h

WBC (/μL)

6000-10,000

1600

1800

3200

3500

5200

15,700

CRP (mg/dL)

< 0.3

2.4

2.3

2.6

2.2

2.9

4.6

IL-6 (pg/mL)

< 4

315,000

66,500

17,600

3850

1080

443

TNF-α (pg/mL)

< 2.8

4.65

1.76

1.53

1.92

3.11

2.08

IL-10 (pg/mL)

< 5

1870

446

79

48

13

9

  1. Abbreviations: CRRT continuous renal replacement therapy, WBC white blood cell count, CRP C-reactive protein, IL-6 Interleukin-6, TNF-α tumor necrosis factor-α, IL-10 Interleukin-10