Fig. 3From: Long-term exposure to pemetrexed induces chronic renal dysfunction in patients with advanced and recurrent non-squamous cell lung cancer: a retrospective studya, b ROC curves of cumulative PEM dose (a) and number of courses from induction therapy (b). a Cutoff value 7000 mg/body (AUC 0.68, TPF 0.29, FPF 0.71, P < 0.01). b Cut-off value 10 courses (AUC 0.71, TPF 0.27, FPF 0.65, P < 0.01). PEM, pemetrexed; ROC, receiver operating characteristics; AUC, area under the curve; TPF, true positive fraction; FPF, false positive fractionBack to article page