| |
Zn ≤ 48 (1st decile)
|
48 < Zn (2nd-10th deciles)
|
P value
|
|---|
|
Number of patients
|
12 (13%)
|
81 (87%)
| |
|
AS
|
6 (50%)
|
13 (16%)
|
< 0.01
|
|
Surgical history of AS
|
1 (8.3%)
|
4 (4.9%)
|
0.58
|
|
Age
|
75.3 ± 12.5
|
70.6 ± 9.9
|
0.034
|
|
Male
|
9 (75%)
|
45 (56%)
|
0.21
|
|
Height (cm)
|
164.9 ± 8.7
|
159.8 ± 8.8
|
0.1
|
|
Dw (kg)
|
57.5 ± 10.9
|
53.4 ± 11.3
|
0.19
|
|
Diabetes
|
3 (25%)
|
22 (27%)
|
0.88
|
|
Dialysis vintage (year)
|
11.3 ± 8.7
|
10.9 ± 7.3
|
0.94
|
|
Zn (μg/dL)
|
45.0 ± 4.3
|
63.7 ± 13.1
|
< 0.01
|
|
ALB (g/dL)
|
3.2 ± 0.4
|
3.5 ± 0.3
|
0.043
|
|
Hb (g/dL)
|
11.1 ± 1.4
|
11.4 ± 1.0
|
0.1
|
|
Ferritin (ng/mL)
|
135.6 ± 45.1
|
119.0 ± 91.2
|
0.12
|
|
Cre (mg/dL)
|
9.4 ± 1.7
|
10.5 ± 2.4
|
0.09
|
|
Ca (mg/dL)
|
9.3 ± 0.4
|
9.3 ± 0.6
|
0.72
|
|
P (mg/dL)
|
5.0 ± 0.8
|
5.1 ± 1.6
|
0.86
|
|
Ca × P
|
46 ± 7.5
|
47.5 ± 14
|
0.95
|
|
P ave
|
5.2 ± 0.8
|
5.2 ± 1.0
|
0.83
|
|
K (mEq/L)
|
5.0 ± 0.6
|
5.0 ± 0.7
|
0.87
|
|
Mg (mg/dL)
|
2.5 ± 0.2
|
2.8 ± 0.4
|
< 0.01
|
|
Cu (μg/dL)
|
90 ± 23
|
87.1 ± 19.1
|
0.68
|
|
iPTH (pg/mL)
|
184.0 ± 112.1
|
133.7 ± 105.3
|
0.11
|
|
LDL-chol (mg/dL)
|
75.9 ± 18.9
|
82.9 ± 25.3
|
0.29
|
|
TAC-BUN
|
48.2 ± 6.6
|
48.5 ± 9.6
|
1
|
|
Kt/V for urea
|
1.44 ± 0.18
|
1.54 ± 0.19
|
0.17
|
|
SBP (mmHg)
|
137.7 ± 19.0
|
142.8 ± 16.7
|
0.43
|
|
Drug
|
|
Vitamin D
|
10 (83%)
|
76 (92%)
|
0.12
|
|
Calcium-containing phosphate binder
|
8 (67%)
|
51 (61%)
|
0.51
|
|
ACE/ARB
|
9 (75%)
|
48 (58%)
|
0.34
|
|
Calcimimetics
|
7 (58%)
|
41 (49%)
|
0.71
|
|
P absorbentsa
|
1.5 ± 0.8
|
2.1 ± 0.9
|
0.024
|
|
Warfarin
|
5 (42%)
|
16 (19%)
|
0.1
|
|
Statins
|
5 (41.7%)
|
24 (29.6%)
|
0.4
|
|
Past history
|
|
IHD
|
5 (41.7 %)
|
22 (27.2 %)
|
0.3
|
|
CVD
|
2 (16.6 %)
|
14 (17.3 %)
|
0.96
|
|
ASO
|
4 (33.3 %)
|
16 (19.8 %)
|
0.29
|
- Data are n (%) and mean (SD). AS aortic stenosis, Dw dry weight, Zn serum zinc, ALB serum albumin, Hb serum hemoglobin level, Cre serum creatinine, Ca serum calcium corrected by serum albumin, P serum phosphate, Ca × P product of Ca and P, P ave average value of serum phosphate during this study, K serum potassium, Mg serum magnesium, Cu serum cupper, iPTH serum intact parathyroid hormone, LDL-chol serum low-density lipoprotein cholesterol, TAC-BUN time-averaged concentration of blood urea nitrogen, SBP systolic blood pressure, ACE/ARB angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker, P absorbents phosphorus adsorbents, IHD ischemic heart disease, CVD cerebrovascular disease, ASO arteriosclerosis obliterans
- aNumber of different P absorbents taken by patients
