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Fig. 3 | Renal Replacement Therapy

Fig. 3

From: Effect of lactate as a peritoneal dialysis fluid buffer on rat peritoneal mesothelial cells

Fig. 3

Effects of lactate on TGF-β and bFGF mRNA expressions of PMCs. Levels of mRNA expression for TGF-β1 (a), TGF-β2 (b), and bFGF (c) for each stimulus time: control group, L5 group, L10 group, L20 group, L40 group, L80 group. **P < 0.01 vs control group. ***P < 0.001 vs control group.#P < 0.0001 vs control group. Levels of mRNA expression for TGF-β1 (d), TGF-β2 (e), and bFGF (f) with each stimulus dose: 6 h, 24 h, 48 h, 72 h. *P < 0.05 vs 6 h. **P < 0.01 vs 6 h. ***P < 0.001 vs 6 h. #P < 0.0001 vs 6 h. TGFβ1 mRNA expression tended to be enhanced upon stimulation with 80 mEq/L (d). TGFβ2 mRNA expression was upregulated in a dose-dependent manner (e). Expression of bFGF mRNA was upregulated in a dose- and time-dependent manner (c, f)

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