Skip to main content

Table 7 Correlation between biochemical tests together and biochemical tests and genetic testing in inherited tubulointerstitial kidney disease and inherited renal hypouricemia

From: Prevalence of inherited changes of uric acid levels in kidney dysfunction including stage 5 D and T: a systematic review

Statistical analysis

ITIKD

iRHUC

Interpretation

Correlation between SCr and sUA

No correlation (p value 0.26)

No correlation (p value 0.07)

Effect of sUA changes on kidney dysfunction and effect of kidney dysfunction on sUA levels changes

Correlation between SCr and FEUA

No correlation (p value 0.139)

No correlation (p value 0.27)

Effect of FEUA changes on kidney dysfunction and effect of kidney dysfunction on FEUA changes

Correlation between eGFR and sUA

No correlation (p value 0.175)

–

Effect of decreased eGFR on sUA changes

Correlation between Hb and sUA levels

No correlation (p value 0.72)

  

Correlation between sUA and exon region

No correlation (p value 0.30)

Presence of correlation (p value 0.037)

Effect of exon region of UMOD and SCL2A9 gene mutations on changes of sUA levels

  1. eGFR estimated glomerular filtration rate, FEUA fractional excretion of uric acid, Hb hemoglobin, iRHUC inherited renal hypouricemia, ITIKD inherited tubulointerstitial kidney disease, SCr serum creatinine, sUA serum uric acid, UMOD uromodulin