A clinical nomogram for the prediction of early mortality in elderly patients initiating dialysis for end-stage renal disease

Yoshida, Masaki; Otsuka, Masanori; Watanabe, Yoshikazu; Harigai, Takako; Sakurai, Noriyuki; Kobatake, Keiko; Yoshida, Hiroaki; Kobayashi, Satsuki; Matsumoto, Takayuki; Sakamoto, Tatsuhiko; Ueki, Kazue

doi:10.1186/s41100-020-0259-y

Table 2 Cox proportional hazards model

From: A clinical nomogram for the prediction of early mortality in elderly patients initiating dialysis for end-stage renal disease

	Univariate Cox proportional hazard models					Multivariate Cox proportional hazard models
	β coefficient	χ²	p value	Hazard ratio	95% CI	β coefficient	χ²	p value	Hazard ratio	95% CI
Age (year)	0.014	0.405	0.525	1.015	0.970–1.061
Sex (female)	− 0.132	0.628	0.428	0.876	0.632–1.214
Body mass index kg/m²	− 0.020	0.560	0.454	0.981	0.932–1.032
Congestive heart failure	0.374	4.213	0.040	1.454	1.017–2.078	0.591	9.852	0.002	1.806	1.249–2.613
Cardiovascular disease	0.381	3.860	0.049	1.464	1.001–2.140	0.467	5.406	0.020	1.594	1.076–2.363
Peripheral vascular disease	0.795	4.136	0.042	2.214	1.029–4.762	0.706	2.911	0.005	2.026	0.900–4.558
Chronic obstructive pulmonary disease	0.878	6.334	0.012	2.406	1.214–4.767	0.895	5.909	0.014	2.474	1.200–5.099
Diabetes mellitus	0.281	0.997	0.318	1.325	0.763–2.299
Diabetes mellitus with end-organ damage	− 0.179	3.636	0.057	0.836	0.696–1.005
Cerebral infarction	0.217	1.368	0.242	1.243	0.863–1.789
Dementia	0.577	10.748	0.001	1.781	1.261–2.514
Collagen disease	0.859	3.538	0.060	2.360	0.965–5.775
Peptic ulcer	0.401	0.314	0.576	1.493	0.367–6.065
Hemiplegia	0.378	12.052	0.001	1.460	1.179–1.808	0.724	10.887	0.001	2.062	1.324–3.213
Mild liver dysfunction	0.137	0.090	0.764	1.147	0.468–2.809
Moderate/severe liver dysfunction	0.068	0.159	0.690	1.070	0.768–1.491
Malignant tumor (no metastasis)	0.605	20.945	0.000	1.831	1.413–2.372	0.691	21.702	0.000	1.995	1.492–2.668
Metastatic malignant tumor	2.000	7.555	0.006	4.331	1.450–12.30	2.090	7.555	0.006	4.668	1.556–14.00
Serum albumin g/dl	− 0.571	18.430	0.000	0.565	0.436–0.733	− 0.453	9.793	0.002	0.634	0.477–0.843
Hemoglobin g/dl	0.021	0.132	0.716	1.021	0.913–1.143
Serum sodium mEq/l	− 0.007	0.193	0.661	0.993	0.961–1.025
Serum potassium mEq/l	0.068	0.801	0.371	1.070	0.923–1.241
eGFR ml/min/1.73 m²	0.059	8.363	0.004	1.061	1.019–1.104
Serum chloride mEq/l	− 0.024	4.148	0.042	0.977	0.955–0.999
Corrected serum calcium mg/dl	0.387	12.290	0.000	1.473	1.186–1.829
Blood urea nitrogen mg/dl	0.005	4.906	0.027	1.005	1.001–1.010
Serum phosphorus mg/dl	0.089	2.477	0.115	1.093	0.978–1.221
Total cholesterol mg/dl	− 0.003	2.783	0.095	0.997	0.994–1.001
C-reactive protein mg/dl	0.060	29.335	0.000	1.062	1.039–1.085
Emergency initiation	0.267	7.078	0.008	1.306	1.073–1.591
Initiation by catheter	0.530	10.176	0.001	1.698	1.227–2.352
Karnofsky Performance Status	− 0.023	38.373	0.000	0.977	0.970–0.984	− 0.018	21.822	0.000	0.981	0.973–0.989
Fracture within 12 months	0.790	9.639	0.002	2.203	1.338–3.628	0.617	6.440	0.011	1.853	1.111–3.089

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ISSN: 2059-1381

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