Univariate Cox proportional hazard models | Multivariate Cox proportional hazard models | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
β coefficient | χ2 | p value | Hazard ratio | 95% CI | β coefficient | χ2 | p value | Hazard ratio | 95% CI | |
Age (year) | 0.014 | 0.405 | 0.525 | 1.015 | 0.970–1.061 | |||||
Sex (female) | − 0.132 | 0.628 | 0.428 | 0.876 | 0.632–1.214 | |||||
Body mass index kg/m2 | − 0.020 | 0.560 | 0.454 | 0.981 | 0.932–1.032 | |||||
Congestive heart failure | 0.374 | 4.213 | 0.040 | 1.454 | 1.017–2.078 | 0.591 | 9.852 | 0.002 | 1.806 | 1.249–2.613 |
Cardiovascular disease | 0.381 | 3.860 | 0.049 | 1.464 | 1.001–2.140 | 0.467 | 5.406 | 0.020 | 1.594 | 1.076–2.363 |
Peripheral vascular disease | 0.795 | 4.136 | 0.042 | 2.214 | 1.029–4.762 | 0.706 | 2.911 | 0.005 | 2.026 | 0.900–4.558 |
Chronic obstructive pulmonary disease | 0.878 | 6.334 | 0.012 | 2.406 | 1.214–4.767 | 0.895 | 5.909 | 0.014 | 2.474 | 1.200–5.099 |
Diabetes mellitus | 0.281 | 0.997 | 0.318 | 1.325 | 0.763–2.299 | |||||
Diabetes mellitus with end-organ damage | − 0.179 | 3.636 | 0.057 | 0.836 | 0.696–1.005 | |||||
Cerebral infarction | 0.217 | 1.368 | 0.242 | 1.243 | 0.863–1.789 | |||||
Dementia | 0.577 | 10.748 | 0.001 | 1.781 | 1.261–2.514 | |||||
Collagen disease | 0.859 | 3.538 | 0.060 | 2.360 | 0.965–5.775 | |||||
Peptic ulcer | 0.401 | 0.314 | 0.576 | 1.493 | 0.367–6.065 | |||||
Hemiplegia | 0.378 | 12.052 | 0.001 | 1.460 | 1.179–1.808 | 0.724 | 10.887 | 0.001 | 2.062 | 1.324–3.213 |
Mild liver dysfunction | 0.137 | 0.090 | 0.764 | 1.147 | 0.468–2.809 | |||||
Moderate/severe liver dysfunction | 0.068 | 0.159 | 0.690 | 1.070 | 0.768–1.491 | |||||
Malignant tumor (no metastasis) | 0.605 | 20.945 | 0.000 | 1.831 | 1.413–2.372 | 0.691 | 21.702 | 0.000 | 1.995 | 1.492–2.668 |
Metastatic malignant tumor | 2.000 | 7.555 | 0.006 | 4.331 | 1.450–12.30 | 2.090 | 7.555 | 0.006 | 4.668 | 1.556–14.00 |
Serum albumin g/dl | − 0.571 | 18.430 | 0.000 | 0.565 | 0.436–0.733 | − 0.453 | 9.793 | 0.002 | 0.634 | 0.477–0.843 |
Hemoglobin g/dl | 0.021 | 0.132 | 0.716 | 1.021 | 0.913–1.143 | |||||
Serum sodium mEq/l | − 0.007 | 0.193 | 0.661 | 0.993 | 0.961–1.025 | |||||
Serum potassium mEq/l | 0.068 | 0.801 | 0.371 | 1.070 | 0.923–1.241 | |||||
eGFR ml/min/1.73 m2 | 0.059 | 8.363 | 0.004 | 1.061 | 1.019–1.104 | |||||
Serum chloride mEq/l | − 0.024 | 4.148 | 0.042 | 0.977 | 0.955–0.999 | |||||
Corrected serum calcium mg/dl | 0.387 | 12.290 | 0.000 | 1.473 | 1.186–1.829 | |||||
Blood urea nitrogen mg/dl | 0.005 | 4.906 | 0.027 | 1.005 | 1.001–1.010 | |||||
Serum phosphorus mg/dl | 0.089 | 2.477 | 0.115 | 1.093 | 0.978–1.221 | |||||
Total cholesterol mg/dl | − 0.003 | 2.783 | 0.095 | 0.997 | 0.994–1.001 | |||||
C-reactive protein mg/dl | 0.060 | 29.335 | 0.000 | 1.062 | 1.039–1.085 | |||||
Emergency initiation | 0.267 | 7.078 | 0.008 | 1.306 | 1.073–1.591 | |||||
Initiation by catheter | 0.530 | 10.176 | 0.001 | 1.698 | 1.227–2.352 | |||||
Karnofsky Performance Status | − 0.023 | 38.373 | 0.000 | 0.977 | 0.970–0.984 | − 0.018 | 21.822 | 0.000 | 0.981 | 0.973–0.989 |
Fracture within 12 months | 0.790 | 9.639 | 0.002 | 2.203 | 1.338–3.628 | 0.617 | 6.440 | 0.011 | 1.853 | 1.111–3.089 |