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Table 2 Summary of the results of prior studies in patients with anti-GBM disease between 2000 and 2020

From: Clinical and immunologic characteristics of Japanese patients with anti-glomerular basement membrane disease: case reports and literature review

Reference

Country

Study period (year)

Sample size (n)

Age (years)

sCr (mg/dl)

Anti-GBM measurement method

eGFR (ml/min/1.73 m2)

Lung involvement(%)

Prednisolone (%)

Cyclophosphamide (%)

Plasmapheresis (%)

Infectious complication (%)

Relapse rate (%)

1-year survival (%)

5-year survival (%)

Levy et al. [7]

UK

1975–1999

81

40

3.6

ELISA

NA

62

100

100

100

NA

3

79

NA

Segelmark et al. [3]

Sweden

1987–1995

79

59

NA

ELISA

NA

21

NA

NA

NA

NA

NA

66*

NA

Li et al. [8]

China

1992–2003

10

59

NA

ELISA or IIF

NA

80

80

80

80

0

0

80

NA

Rutgers et al. [9]

Netherlands

1978–2003

24

57

9.9

ELISA

NA

NA

54

54

54

NA

NA

91

NA

Hirayama et al. [5]

Japan

1989–2000

47

51

7.5

NA

NA

23

85

36

55

NA

14

67*

NA

Kitagawa et al. [4]

Japan

1995–2005

16

61

8.2

NA

NA

25

NA

NA

NA

NA

NA

88

NA

Cui et al. [2]

China

1998–2008

221

39

9.5

ELISA

NA

46

80

34

76

NA

NA

73

NA

Dammacco et al. [10]

Italy

2003–2012

10

49

NA

ELISA

NA

60

100

100

100

NA

20

80

NA

Alchi et al. [11]

UK

1991–2011

43

53

NA

Radioimmunoassay

NA

40

74

74

74

NA

0

88

NA

Huart et al. [12]

France

1983–2006

122

31

7.2

ELISA

NA

91

97

84

100

NA

NA

87

NA

Canney et al. [13]

Ireland

2003–2014

79

63

NA

ELISA

NA

98

NA

NA

NA

NA

NA

62

24

McAddo et al. [14]

Czech, UK, and Sweden

2000–2013

78

61

3.3

ELISA or IIF

20§

38

100

92

89

NA

0

86

NA

Marques et al. [15]

France

1981–2017

119

54

7.2

ELISA

NA

45

97

82

82

2

3

95

92

Caillard et al. [16]

France

1997–2017

201

53

7.4

IIF and/or antigen-specific immunoassay

NA

37

97

81

77

58

NA

92

79

Our case series

Japan

2000–2020

12

70

8.5

ELISA

5

42

100

0

67

3

8

82

68

  1. The proportions combined the proportion of oral prednisolone and that of methylprednisolone pulse therapy
  2. GBM glomerular filtration rate, eGFR estimated glomerular filtration rate, ELISA enzyme-linked immunosorbent assay, NA not available, IIF indirect immunofluorescence, sCr serum creatinine level
  3. *6-month survival
  4. § The Modified Diet in Renal Disease equation was used