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Table 1 Patient background, dialysis condition, serum chemistries, comorbidities, and prescription status

From: Prescription characteristics of phosphate binders in a high pill burden for hemodialysis patients

Patients n 533
Gender (male) n (%) 362 (67.9)
Age years 71.3 (63.8-78.0)
Dialysis vintage years 5.5 (2.1-10.8)
Age of starting dialysis years 63.9 (52.8-73.1)
Dialysis Modality
 HD n (%) 306 (57.4)
 On-line HDF n (%) 227 (42.6)
Time
 < 4 hr n (%) 74 (13.9)
 4 hr n (%) 443 (83.1)
 4.5 hr ≤ n (%) 16 (3.0)
Blood flow
 < 200 mL/min n (%) 105 (19.7)
 200 mL/min n (%) 214 (40.2)
 210 mL/min ≤ n (%) 214 (40.2)
Dialysate Ca
 2.5 mEq/L n (%) 365 (68.5)
 3.0 mEq/L n (%) 168 (31.5)
Serum corrected Ca mg/dL 8.70 ± 0.61
Serum P mg/dL 5.37 ± 1.17
Serum i-PTH pg/mL 182 (120-257)
Comorbidities
 Diabetes mellitus (DM) n (%) 310 (58.2)
 Heart failure n (%) 155 (29.1)
 Angina n (%) 85 (15.9)
 Myocardial infarction n (%) 26 (4.9)
 Arrhythmia / Extrasystes n (%) 80 (15.0)
 Peripheral vascular disease n (%) 88 (16.5)
 Cerebral / Brainstem infarction n (%) 106 (19.9)
 Neurologic / Psychiatric disease n (%) 78 (14.6)
 Insomnia n (%) 92 (17.3)
 Gastointestinal disease n (%) 332 (62.3)
 Constipation n (%) 141 (26.5)
 Diarrhea n (%) 24 (4.5)
 Respiratory disease n (%) 92 (17.3)
 Hepatobiliary disease n (%) 132 (24.8)
 Pancreatic disease n (%) 27 (5.1)
 Thyroid disease n (%) 52 (9.8)
 Ocular disease n (%) 263 (49.3)
 Joint and bone disease n (%) 221 (41.5)
 Previous fracture n (%) 65 (12.2)
 Malignancy (including history) n (%) 135 (25.3)
 Gangrene, Cellulitis, Decubitus, Skin ulcer n (%) 31 (5.8)
 Previous parathyroidectomy (PTx) n (%) 10 (1.9)
Prescription medical doctors n 26
Different types of oral drugs
 mean±SD types/month/patient 9.2 ± 3.2
 median (Q1-Q3) types/month/patient 9 (7-11)
Total pill burden
 mean±SD pills/day/patient 15.1 ± 7.6
 median (Q1-Q3) pills/day/patient 14.1 (10.0-18.7)
  1. HD hemodialysis, HDF hemodialysis filtration, Q1 first quartile, Q3 third quartile
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