From: Prescription characteristics of phosphate binders in a high pill burden for hemodialysis patients
Patients | n | 533 |
Gender (male) | n (%) | 362 (67.9) |
Age | years | 71.3 (63.8-78.0) |
Dialysis vintage | years | 5.5 (2.1-10.8) |
Age of starting dialysis | years | 63.9 (52.8-73.1) |
Dialysis Modality | ||
HD | n (%) | 306 (57.4) |
On-line HDF | n (%) | 227 (42.6) |
Time | ||
< 4 hr | n (%) | 74 (13.9) |
4 hr | n (%) | 443 (83.1) |
4.5 hr ≤ | n (%) | 16 (3.0) |
Blood flow | ||
< 200 mL/min | n (%) | 105 (19.7) |
200 mL/min | n (%) | 214 (40.2) |
210 mL/min ≤ | n (%) | 214 (40.2) |
Dialysate Ca | ||
2.5 mEq/L | n (%) | 365 (68.5) |
3.0 mEq/L | n (%) | 168 (31.5) |
Serum corrected Ca | mg/dL | 8.70 ± 0.61 |
Serum P | mg/dL | 5.37 ± 1.17 |
Serum i-PTH | pg/mL | 182 (120-257) |
Comorbidities | ||
Diabetes mellitus (DM) | n (%) | 310 (58.2) |
Heart failure | n (%) | 155 (29.1) |
Angina | n (%) | 85 (15.9) |
Myocardial infarction | n (%) | 26 (4.9) |
Arrhythmia / Extrasystes | n (%) | 80 (15.0) |
Peripheral vascular disease | n (%) | 88 (16.5) |
Cerebral / Brainstem infarction | n (%) | 106 (19.9) |
Neurologic / Psychiatric disease | n (%) | 78 (14.6) |
Insomnia | n (%) | 92 (17.3) |
Gastointestinal disease | n (%) | 332 (62.3) |
Constipation | n (%) | 141 (26.5) |
Diarrhea | n (%) | 24 (4.5) |
Respiratory disease | n (%) | 92 (17.3) |
Hepatobiliary disease | n (%) | 132 (24.8) |
Pancreatic disease | n (%) | 27 (5.1) |
Thyroid disease | n (%) | 52 (9.8) |
Ocular disease | n (%) | 263 (49.3) |
Joint and bone disease | n (%) | 221 (41.5) |
Previous fracture | n (%) | 65 (12.2) |
Malignancy (including history) | n (%) | 135 (25.3) |
Gangrene, Cellulitis, Decubitus, Skin ulcer | n (%) | 31 (5.8) |
Previous parathyroidectomy (PTx) | n (%) | 10 (1.9) |
Prescription medical doctors | n | 26 |
Different types of oral drugs | ||
mean±SD | types/month/patient | 9.2 ± 3.2 |
median (Q1-Q3) | types/month/patient | 9 (7-11) |
Total pill burden | ||
mean±SD | pills/day/patient | 15.1 ± 7.6 |
median (Q1-Q3) | pills/day/patient | 14.1 (10.0-18.7) |