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Fig. 1 | Renal Replacement Therapy

Fig. 1

From: Suitability of α1-microglobulin reduction rate as a biomarker of removal efficiency of online hemodiafiltration: a retrospective cohort study

Fig. 1

Relationship between reduction rate and amount of albumin leakage. No significant correlation is found between the amount of alb leakage and β2-MG reduction rate. Since β2-MG is primarily removed by diffusion as well as convection, this indicates that high-efficiency removal is possible with little to no alb leakage. α1-MG cannot be removed with high efficiency without some degree of alb leakage. Furthermore, as 30–50% of α1-MG is bound to dimeric IgA in renal failure, the maximum reduction rate is around 60%

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