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Table 2 Patient background

From: Effectiveness of a treatment algorithm for hemodialysis-associated pruritus in terms of changes in medications

 

2009

2013

2014

2015

2016

2017

2018

P value

Number of patients

89

131

164

190

181

215

224

 

Men/women

62 (69.7)/27 (30.3)

89 (67.9)/42 (32.1)

102 (62.2)/62 (37.8)

125 (65.8)/65 (34.2)

113 (62.4)/68 (37.6)

136 (63.3)/79 (36.7)

140 (62.5)/84 (37.5)

0.801*

Median age (IQR), years

68 (61.0–76.5)

71 (64.0–77.0)

71 (65.0–78.0)

72 (65.0–78.0)

72 (65.0–79.0)

71 (66.0–78.0)

72 (66.0–79.0)

0.127**

Median duration of HD (IQR), months

63 (29.0–98.0)

75 (27.0–137.0)

68.5 (32.0–136.5)

60 (31.5–119.3)

65 (34.0–142.0)

71 (32.0–136.0)

77 (33.0–151.0)

0.402**

Primary cause of CKD

 Diabetes mellitus

41 (46.1)

65 (49.6)

78 (47.6)

94 (49.5)

84 (46.4)

98 (45.6)

106 (47.3)

 

 Chronic glomerulonephritis

24 (27.0)

35 (26.7)

41 (25.0)

41 (21.6)

41 (22.7)

50 (23.3)

42 (18.8)

 

 Nephrosclerosis

6 (6.7)

8 (6.1)

20 (12.2)

20 (10.5)

22 (12.2)

26 (12.1)

34 (15.2)

0.787*

 Other

6 (6.7)

8 (6.1)

9 (5.5)

15 (7.9)

17 (9.4)

22 (10.2)

21 (9.4)

 

 Unknown

12 (13.5)

15 (11.5)

16 (9.8)

20 (10.5)

17 (9.4)

19 (8.8)

21 (9.4)

 

Dialysis method

 HD

89 (100)

121 (93.8)

142 (86.6)

137 (72.1)

103 (56.9)

92 (42.8)

78 (34.8)

< 0.001*

 OHDF

0 (0)

8 (6.2)

18 (11.0)

47 (24.7)

75 (41.4)

113 (52.6)

129 (57.6)

 I-HDF

0 (0)

0 (0)

4 (2.4)

6 (3.2)

3 (1.7)

10 (4.7)

17 (7.6)

PMMA membrane dialyzer

4 (4.5)

17 (13.0)

42 (25.6)

45 (23.7)

36 (19.9)

45 (20.9)

33 (14.7)

< 0.001*

Median spKt/Vurea [IQR]

1.6 [1.4, 1.8]

1.6 [1.4, 1.8]

1.7 [1.4, 1.9]

1.6 [1.5, 1.8]

1.7 [1.5, 1.8]

1.7 [1.5, 1.8]

1.7 [1.5, 1.9]

< 0.01**

  1. Data are presented as number (%), unless stated otherwise
  2. P values were calculated using Fisher’s exact test (*) or Kruskal-Wallis test (**)
  3. CKD chronic kidney disease, HD hemodialysis, I-HDF intermittent infusion hemodiafiltration, IQR interquartile range, OHDF online hemodiafiltration, PMMA polymethylmethacrylate, spKt/Vurea single-pool Kt/Vurea
  4. The median spKt/Vurea values in 2016 (p < 0.05), 2017 (p < 0.05), and 2018 (p < 0.01) were significantly different from that in 2009