Table 4 Changes in the number of patients by drug
| Â | 2009 (n = 89) | 2013 (n = 131) | 2014 (n = 164) | 2015 (n = 190) | 2016 (n = 181) | 2017 (n = 215) | 2018 (n = 224) | P value* |
|---|---|---|---|---|---|---|---|---|
Moisturizers | 31 (34.8) | 85 (64.9) | 134 (81.7) | 151 (79.5) | 142 (78.5) | 184 (85.6) | 201 (89.7) | < 0.001 |
Topical steroids | 42 (47.2) | 68 (51.9) | 70 (42.7) | 78 (41.1) | 83 (45.9) | 87 (40.5) | 80 (35.7) | 0.085 |
Topical antihistamines | 4 (4.5) | 4 (3.1) | 1 (0.6) | 0 (0.0) | 1 (0.6) | 0 (0.0) | 1 (0.4) | < 0.005 |
Other topical drugs | 17 (19.1) | 13 (9.9) | 8 (4.9) | 19 (10.0) | 35 (19.3) | 34 (15.8) | 28 (12.5) | < 0.005 |
Anti-allergy injections | 29 (32.6) | 10 (7.6) | 4 (2.4) | 1 (0.5) | 2 (1.1) | 2 (0.9) | 3 (1.3) | < 0.001 |
Oral antihistamines | 36 (40.4) | 35 (26.7) | 19 (11.6) | 22 (11.6) | 13 (7.2) | 24 (11.2) | 24 (10.7) | < 0.001 |
Nalfurafine hydrochloride | 0 (0.0) | 31 (23.7) | 37 (22.6) | 40 (21.1) | 39 (21.5) | 29 (13.5) | 32 (14.3) | < 0.001 |