Table 2 Treatment events including hemodialysis prescription

1

11:35

Fomepizole given at local ED.

1

16:40

> 156

1

20:56

Treatment #1 started. Tablo® machine, Revaclear™ dialyzer, right IJ 15-cm 12-French Power-Trialysis™ catheter, lines reversed, Qb 350 mL/min, Qd 300 mL/min, UF 75 mL/h.

1

22:15

Circuit clotted.

1

22:44

Restarted with circuit lines changed and in-line heparin^† added. Qb 300 mL/min, Qd 300 mL/min.

1

22:45

Fomepizole 950 mg IV.

1

23:05

Due to poor flows, Qb dropped further to 250 mL/min.

1

23:14

Treatment stopped again. Unable to aspirate from either line. New vascular access placed (right femoral 30-cm Power-Trialysis catheter).

2

0:45

Fomepizole 950 mg IV.

2

0:56

Treatment restarted using femoral line. Qb 350 mL/min, Qd 300 mL/min, UF 200 mL/h.

2

4:04

Treatment #1 completed.

2

7:51

64.9

2

9:19

Fomepizole 1500 mg IV.

2

10:45

Treatment #2 started. Tablo machine, Revaclear dialyzer, access 1-and-1 (right IJ arterial, right femoral venous return), Qb 350 mL/min, Qd 300 mL/min, UF 337 mL/h.

2

14:00

UF dropped to 117 mL/h.

2

14:45

7.2*

*Level measured from the dialysis catheter during HD.

15:46

Fomepizole 1500 mg IV.

2

15:50

Treatment #2 completed.

2

22:36

15

3

0:50

Treatment #3 started. Gambro Phoenix™ machine, Revaclear dialyzer, Qb 350 mL/min, Qd 700 mL/min, UF 100 mL/h.

3

4:10

Circuit clotted; treatment stopped.

3

5:35

Treatment #3 restarted. Qb 350 mL/min, Qd 700 mL/min, UF 200 mL/h.

3

6:35

Treatment #3 completed.

3

8:54

3.4

3

10:25

3.1

3

12:42

2.2

4

4:00

ND