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Table 3 Selected studies of plasma amino acids measurement during HD treatment

From: An increase in circulating levels of branched-chain amino acids during hemodialysis with regard to protein breakdown: three case reports

Author (reference)

Measured timing

No. of measured AA kinds

AA supplement

Meal during HD

HD/HDF (h)

Etiology (N)

kT/V

Blood flow rate (mL/min)

Surface area of dialyzer (m2)

Dialysate glucose (mg/dL)

Membrane (N)

Study aim

Ikizler [28]

B, A

25

No

No

HD (4 h)

D(3), ND(6)

1.5

300–400

1.8

Not described

PS, PMMA CU

Functional comparison of membranes (between PS, PMMA and CU)

Navarro [3]

B, A

22

Yes, no

no

HD (4 h)

ND(10)

1.23

300

1.7

100

PAN

Evaluation of the effect of intradialytic amino acid solution supply

Gil [29]

B, A

21

No

No

HD

D(3), ND(7)

1.52

2, 50, 300

1.4

Not described

PAES

Functional comparison of membranes (between high flux and low flux)

Fujiwara [8]

B, A

28

Yes, no

No

HDF (5 h)

D(2)

1.7

240

2.1

100

PS

Evaluation of the effect of intradialytic amino acid solution supply

Murtas [30]

B, A

20

No

No

HD,HDF(4 h)

ND(10)

1.37

240

1.8

100

PS

Functional comparison of modalities (between HD and HDF)

Murtas [31]

B

20

No

No

HD,HDF(4 h)

ND(10)

1.37

Not described

1.8

100

PS

Functional comparison of modalities (between HD and HDF)

Hendriks [32]

B, A

22

No

Yes

HD (4 h)

D(2), ND(8)

Not described

300–400

1.7, 2.2

100

PS (7) PAES (3)

Evaluation of the effect of food intake

  1. AA amino acids, B before HD, A after HD, D diabetic, ND non-diabetic, PS polysulfone, PMMA polymethylmethacrylate, CU cuprophane, PAN polyacrylonitrile, PAES polyarylethersulfone