Clinical features and outcomes of four atypical hemolytic uremic syndrome cases at a single institution in Miyazaki Prefecture from 2015 to 2019

Table 3 Genetic variants of aHUS in our study

		Case 1			Case 2			Case 3			Case 4
Genetic analysis	Complement factor	Amino acid substitution	ExAC All	HGVD by Kyoto Univ	Amino acid substitution	ExAC All	HGVD by Kyoto Univ	Amino acid substitution	ExAC All	HGVD by Kyoto Univ	Amino acid substitution	ExAC All	HGVD by Kyoto Univ
	CFH	H402Y	0.6721	C>T:0.9309	V62I	0.321	G > A:0.4143	H402Y	0.6721	C>T:0.9309	V62I	0.321	G>A:0.4115
		E936D	0.1955	G>T:0.4500	H402Y	0.6721	C>T:0.9309	E936D	0.1955	G>T:0.4500	H402Y	0.6721	C>T:0.9315
					V837I	0.001306	G>A:0.0194				E936D	0.1955	G>T:0.4482
	THBD	A473V	0.1997	G>A:0.2668				A473V	0.1997	G>A:0.2668	A473V	0.1997	C>T:0.263
Trigger		Renal transplantation			Influenza AIP/DIC			Influenza-mimicking symptoms AIP/DIC			SFTS

ISSN: 2059-1381