Case no | Age | Sex | Primary disease | ABO | Delayed graft function | Time of DSA detection (post−Tx) | HLA | MFI | Reason for HLA screening | Biopsy | Treatment | Outcome |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 44 | Male | IgA nephropathy | Compatible | With | 275 months | DR13 DQ6 | 11226 19056 | Protocol | cABMR | AZA→MMF | Alive with graft function |
2 | 43 | Male | Chronic glomerulonephritis | Compatible | Without | 252 months | DQ6 | 20866 | Serum Cr↑ | cABMR+ CNI | Steroid pulse, PE, IVIG, Rit, mTOR | Alive with graft function |
3 | 48 | Male | Chronic glomerulonephritis | Compatible | Without | 251 months | DR53 | 21566 | Protocol | cABMR | AZA→MMF, steroid pulse | Alive with graft loss |
4 | 61 | Female | Unknown disease | Compatible | With | 142 months | DR53 DQ4 DQ9 | 22850 21803 21530 | Serum Cr↑ | cABMR | Steroid pulse, PE, IVIG, Rit, mTOR | Alive with graft loss |
5 | 54 | Female | ADPKD | Compatible | Without | 141 months | DQ7 | 7246 | Protocol | Not definition for cABMR | Steroid pulse, PE, IVIG | Alive with graft function |
6 | 53 | Male | Sarcoidosis | Compatible | Without | 88 months | DR53 | 3326 | Protocol | nothing particular | − | Alive with graft function |
7 | 44 | Male | IgA nephropathy | Compatible | Without | 52 months | DR51 | 15056 | Serum Cr↑ Proteinuria↑ | IgA+ cABMR | Steroid pulse, PE, IVIG, Rit | Alive with graft function |
8 | 77 | Male | IgA nephropathy | Compatible | Without | 18 months | DQ7 | 14915 | Serum Cr↑ | Borderline change | rATG, steroid pulse, PE, IVIG | Alive with graft function |