Duration, y | Group A | Group B | Group C | ||||||
---|---|---|---|---|---|---|---|---|---|
1 | 10 | P value | 10 | 20 | P value | 20 | 30 | P value | |
DW, kg | 61.5 ± 11.2 | 61.5 ± 12.3 | 0.967 | 55.0 ± 10.6 | 53.7 ± 9.5 | 0.247 | 58.7 ± 8.3 | 57.4 ± 9.5 | 0.391 |
BW, kg | 61.4 ± 11.1 | 61.7 ± 12.4 | 0.778 | 54.8 ± 10.5 | 54.0 ± 9.6 | 0.442 | 58.7 ± 8.5 | 57.3 ± 9.6 | 0.386 |
Fat mass, kg | 12.7 ± 3.7 | 13.5 ± 3.8 | 0.292 | 11.7 ± 4.5 | 11.6 ± 4.2 | 0.935 | 13.1 ± 3.3 | 13.6 ± 4.5 | 0.638 |
Muscle mass, kg | 46.0 ± 9.4 | 45.6 ± 9.5 | 0.383 | 40.9 ± 8.4 | 40.0 ± 7.9 | 0.113 | 43.0 ± 7.4 | 41.2 ± 7.1 | 0.012 |
LBM, kg | 48.8 ± 9.9 | 48.2 ± 9.9 | 0.230 | 43.1 ± 8.9 | 42.4 ± 8.2 | 0.245 | 45.6 ± 7.8 | 43.7 ± 7.5 | 0.012 |
BCM, kg | 30.2 ± 6.2 | 29.6 ± 6.2 | 0.014 | 26.4 ± 4.7 | 25.8 ± 4.9 | 0.178 | 28.1 ± 4.8 | 26.6 ± 4.5 | 0.004 |
ECW, L | 11.1 ± 2.3 | 11.4 ± 2.4 | 0.065 | 9.9 ± 2.2 | 10.1 ± 2.2 | 0.179 | 10.5 ± 1.9 | 10.6 ± 2.0 | 0.584 |
ICW, L | 18.0 ± 3.7 | 17.5 ± 3.7 | 0.002 | 15.8 ± 3.2 | 15.1 ± 2.8 | 0.005 | 16.6 ± 2.8 | 15.5 ± 2.6 | 0.002 |
TBW, L | 29.0 ± 6.0 | 28.8 ± 6.0 | 0.432 | 25.7 ± 5.3 | 25.2 ± 4.9 | 0.212 | 27.2 ± 4.7 | 26.1 ± 4.5 | 0.016 |
ECW/TBW | 0.381 ± 0.010 | 0.394 ± 0.016 | < 0.001 | 0.383 ± 0.015 | 0.399 ± 0.019 | < 0.001 | 0.387 ± 0.012 | 0.405 ± 0.014 | < 0.001 |
ECW/ICW | 0.615 ± 0.027 | 0.652 ± 0.044 | < 0.001 | 0.621 ± 0.040 | 0.665 ± 0.054 | < 0.001 | 0.633 ± 0.031 | 0.683 ± 0.039 | < 0.001 |
BUN, mg/dL | 69 ± 17 | 65 ± 12 | 0.217 | 70 ± 11 | 61 ± 11 | 0.003 | 78 ± 7 | 72 ± 9 | 0.216 |
Cr, mg/dL | 11.5 ± 2.0 | 13.0 ± 2.3 | < 0.001 | 12.3 ± 1.4 | 11.5 ± 2.0 | 0.027 | 13.0 ± 2.3 | 11.7 ± 2.1 | 0.024 |
CRP, mg/dL | 0.10 (0.00–0.20) | 0.08 (0.06–0.37) | 0.012 | 0.00 (0.00–0.10) | 0.07 (0.03–0.11) | 0.007 | 0.20 (0.00–0.20) | 0.13 (0.05–0.16) | 0.051 |
n-PCR, g/kg/day | 0.86 (0.73–0.93) | 0.91 (0.75–1.04) | 0.178 | 0.90 (0.79–1.01) | 0.94 (0.85–1.01) | 0.507 | 1.05 (1.01–1.11) | 0.98 (0.90–1.03) | 0.173 |
Alb, g/dL | 3.7 ± 0.3 | 3.7 ± 0.3 | 0.703 | 3.6 ± 0.2 | 3.7 ± 0.3 | 0.114 | 3.6 ± 0.3 | 3.8 ± 0.3 | 0.068 |
Kt/V | 1.21 ± 0.25 | 1.40 ± 0.25 | 0.217 | 1.37 ± 0.23 | 1.52 ± 0.30 | 0.045 | 1.29 ± 0.27 | 1.57 ± 0.31 | 0.002 |