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Table 2 Incidence of events

From: Cardiovascular events by different target hemoglobin levels in ESA-hyporesponsive hemodialysis patients: a multicenter, open-label, randomized controlled study

Cardiovascular events

Number of patients

Number of events

Ratio (%)

HR

95% CI

P value

Proactive treatment group

156

9

5.8

0.43

0.19

0.96

0.04

Maintenance treatment group

148

18

12.2

Detail of cardiovascular events

Proactive treatment group (n = 156)

Maintenance treatment group

Number

Ratio (%)

Number

Ratio (%)

Total cardiovascular events

9

5.8

18

12.2

Cardiac death

5

3.2

7

4.7

Fatal myocardial infarction

1

0.6

1

0.7

Death due to heart failure

1

0.6

1

0.7

Sudden cardiac death

3

1.9

5

3.4

Acute coronary syndrome requiring hospitalization

2

1.3

3

2.0

Non-fatal myocardial infarction

1

0.6

0

0.0

Unstable angina

2

1.3

3

2.0

Heart failure requiring hospitalization

3

1.9

9

6.1

Cerebrovascular events

Number of patients

Number of events

Ratio (%)

HR

95% CI

P value

Proactive treatment group

156

8

5.1

0.87

0.33

2.32

0.78

Maintenance treatment group

148

8

5.4

Composite events

Number

Number of events

Ratio (%)

HR

95% CI

P value

Proactive treatment group

156

17

10.9

0.59

0.32

1.09

0.09

Maintenance treatment group

148

25

16.9

All-cause deaths

Number

Number of events

Ratio (%)

HR

95% CI

P value

Proactive treatment group

156

18

11.5

0.97

0.50

1.88

0.93

Maintenance treatment group

148

17

11.5

 
  1. HR and its 95%CI, P values were obtained by Cox proportional hazards model. Multiple answers allowed
  2. HR hazard ratio, CI confidence interval