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  1. Okinoerabu Island and Tokunoshima Island lie in the sea to the south of the Japanese mainland, about 100 km north of Okinawa and about 500 km south of Kyushu. There are no facilities that specialize in kidney ...

    Authors: Hajime Hirano, Ryoichi Maenosono, Tomohisa Matsunaga, Hirofumi Uehara, Hayahito Nomi, Takuya Tsujino, Naoki Tanda, Kenkichi Saito, Taizo Uchimoto, Naokazu Ibuki, Teruo Inamoto, Yoshihiro Tokeshi and Haruhito Azuma
    Citation: Renal Replacement Therapy 2017 3:46
  2. Pneumonia is common in hemodialysis (HD) patients and has a poor prognosis, but there is little information on an accurate method for evaluating the severity of pneumonia, which is closely associated with prog...

    Authors: Makoto Harada, Takeshi Masubuchi, Kazuaki Fujii, Yukifumi Kurasawa, Tohru Ichikawa and Mamoru Kobayashi
    Citation: Renal Replacement Therapy 2017 3:39
  3. Ferric citrate hydrate (FCH), an iron-based phosphate binder, affects mineral and iron metabolism in patients with chronic kidney disease (CKD). The long-term impact of FCH on iron overload is unknown. With th...

    Authors: Maki Hiratsuka, Katsushi Koyama, Kinya Sengo, Jun Yamamoto, Aiko Narita, Chiharu Ito, Satoshi Kominato, Arata Hibi, Keisuke Kamiya, Rumi Miyahara, Junichi Fujikawa and Toshiyuki Miura
    Citation: Renal Replacement Therapy 2017 3:37
  4. Iron-based phosphate binders are widely used in hemodialysis, to avoid the increased mortality associated with high serum phosphate in dialysis patients. However, comparative studies on the effects of phosphat...

    Authors: Takeo Ishii, Yukiko Nakajima and Kunio Oyama
    Citation: Renal Replacement Therapy 2017 3:38
  5. Peritoneal dialysis peritonitis remains a significant cause of morbidity for peritoneal dialysis patients and the main reason for conversion from peritoneal dialysis to hemodialysis. As the characteristics of ...

    Authors: Vui Eng Phui, Clare Hui Hong Tan, Chee Kean Chen, Kee Hoe Lai, Kwek Foong Chew, Hock Hin Chua, Laura Lui Sian Ngu and Lawrence Wei Soon Hii
    Citation: Renal Replacement Therapy 2017 3:35
  6. Newly formed membrane (NFM) on the peritoneal membrane proper is a unique pathological hallmark of encapsulating peritoneal sclerosis (EPS), but its definition and diagnostic significance have not been well de...

    Authors: Kazuho Honda, Chieko Hamada, Kunio Kawanishi, Masaaki Nakayama, Masanobu Miyazaki and Yasuhiko Ito
    Citation: Renal Replacement Therapy 2017 3:33
  7. The production of presepsin has been shown to be strongly related to bacterial phagocytosis. The purpose of the present study is to compare the usefulness of presepsin for diagnosing localized skin wound infec...

    Authors: Jun Shiota, Hitoshi Tagawa, Norihiko Ohura and Hitoshi Kasahara
    Citation: Renal Replacement Therapy 2017 3:31
  8. The Geriatric Nutritional Risk Index (GNRI) is a nutritional screening method primarily developed for elderly people; it is also reported to be useful for predicting mortality in patients on maintenance dialys...

    Authors: Akihito Tanaka, Daijo Inaguma, Hibiki Shinjo, Minako Murata and Asami Takeda
    Citation: Renal Replacement Therapy 2017 3:27
  9. Hemodialysis with polymethylmetacrylate (PMMA) membrane dialyzers allows unique protein adsorption. New PMMA dialyzers should demonstrate equivalent protein adsorption, but improved hemocompatibility.

    Authors: Ikuto Masakane, Shiho Esashi, Asami Yoshida, Tetsuro Chida, Hiroaki Fujieda, Yoshiyuki Ueno and Hiroyuki Sugaya
    Citation: Renal Replacement Therapy 2017 3:32
  10. Acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) is associated with high mortality in critically ill patients. However, the optimal timing to initiate CRRT in patients with AKI i...

    Authors: Jun Suzuki, Tetsu Ohnuma, Hidenori Sanayama, Kiyonori Ito, Takayuki Fujiwara, Hodaka Yamada, Alan Kawarai Lefor and Masamitsu Sanui
    Citation: Renal Replacement Therapy 2017 3:30
  11. The number of older dialysis patients is increasing in many countries. For example, the trend is linked to the increase in the dialysis patients 70 years of age and over in Japan. Older dialysis patients often...

    Authors: Norio Hanafusa, Kosaku Nitta and Ken Tsuchiya
    Citation: Renal Replacement Therapy 2017 3:29
  12. Although it is believed that chronic kidney disease (CKD) in patients with ischemic heart disease (IHD) negatively affects physical activity after discharge, its actual influence on the physical activity of pa...

    Authors: Ryota Matsuzawa, Takashi Masuda, Kentaro Kamiya, Nobuaki Hamazaki, Kohei Nozaki, Shinya Tanaka, Emi Maekawa and Junya Ako
    Citation: Renal Replacement Therapy 2017 3:28
  13. Sepsis due to microbial invasion often causes multiple organ failure (MOF), including acute kidney injury (AKI), with high mortality rates in serious cases. Hence, there is an urgent need for diagnostic biomar...

    Authors: Eiichi Sato, Atsuko Kamijo-Ikemori, Tsuyoshi Oikawa, Aya Okuda, Takeshi Sugaya, Kenjiro Kimura, Tsukasa Nakamura and Yugo Shibagaki
    Citation: Renal Replacement Therapy 2017 3:26
  14. Psychonephrology is the field of study encompassing nephrology, psychiatry, and psychosomatic medicine, which is based on the concept of consultation-liaison within the biopsychosocial model of mind–body unity...

    Authors: Yoichi Ohtake
    Citation: Renal Replacement Therapy 2017 3:25
  15. Renal anemia is a complication of chronic kidney disease. Guidelines for safe and effective treatment in patients with renal anemia are needed. The Japanese Society for Dialysis Therapy (JSDT) published guidel...

    Authors: Hiroyasu Yamamoto, Shinichi Nishi, Tadashi Tomo, Ikuto Masakane, Kazuhide Saito, Masaomi Nangaku, Motoshi Hattori, Takahiro Suzuki, Satoshi Morita, Akira Ashida, Yasuhiko Ito, Takahiro Kuragano, Yasuhiro Komatsu, Ken Sakai, Yoshiharu Tsubakihara, Kazuhiko Tsuruya…
    Citation: Renal Replacement Therapy 2017 3:36
  16. For patients undergoing hemodialysis, continuing in labor is very challenging and many patients have difficulty in current and/or previous workplaces. The objective of the present study is to clarify the deter...

    Authors: Hideyo Tsutsui, Kyoko Nomura, Aya Ishiguro, Yoshinari Tsuruta, Sawako Kato, Yoshinari Yasuda, Shunya Uchida and Yoshiharu Oshida
    Citation: Renal Replacement Therapy 2017 3:23
  17. We recently demonstrated, using an index of recently synthesized hemoglobin, reticulocyte hemoglobin (Ret-Hb), that iron administration remarkably improves hemoglobin (Hb) synthesis during the period of high a...

    Authors: Tomoyuki Kawano, Tadashi Kuji, Tetsuya Fujikawa, Eiko Ueda, Midori Shino, Satoshi Yamaguchi, Toshimasa Ohnishi, Kouichi Tamura, Nobuhito Hirawa and Yoshiyuki Toya
    Citation: Renal Replacement Therapy 2017 3:20
  18. Since 2009, the peritoneal dialysis (PD) registry has been carried out as part of Japanese Society for Dialysis Therapy (JSDT) Renal Data Registry with the cooperation of Japanese Society for Peritoneal Dialys...

    Authors: Ikuto Masakane, Takeshi Hasegawa, Satoshi Ogata, Naoki Kimata, Shigeru Nakai, Norio Hanafusa, Takayuki Hamano, Kenji Wakai, Atsushi Wada and Kosaku Nitta
    Citation: Renal Replacement Therapy 2017 3:21
  19. The Scientific Academy Committee of Japanese Society for Dialysis Therapy (JSDT) has developed 14 clinical practice guidelines (CPGs) and their revised editions independently or in cooperation with other organ...

    Authors: Kosaku Nitta, Ikuto Masakane, Tadashi Tomo, Kenji Tsuchida, Kiyoshi Ikeda, Tomonari Ogawa, Eiichiro Kanda, Yoshihiko Kanno, Yasuhiro Komatsu, Masatomo Taniguchi, Fumika Taki, Takeshi Hasegawa, Norio Hanafusa, Takayuki Hamano, Masafumi Fukagawa, Jun Minakuchi…
    Citation: Renal Replacement Therapy 2017 3:34
  20. In recent years, the use of chest ultrasonography to detect lung water has received growing attention in clinical research. Estimation of the number of B-lines using lung ultrasound is now a standard method fo...

    Authors: Shinzo Kuzuhara, Shigeru Otsubo, Katsuya Kajimoto, Takashi Akiba and Kosaku Nitta
    Citation: Renal Replacement Therapy 2017 3:17
  21. Peritonitis is an important complication of peritoneal dialysis. Several animal peritonitis models have been described, including bacterial and fungal models that are useful for studying inflammation in perito...

    Authors: Yasuhiko Ito, Hiroshi Kinashi, Takayuki Katsuno, Yasuhiro Suzuki and Masashi Mizuno
    Citation: Renal Replacement Therapy 2017 3:16
  22. There are very few oral antidiabetic drugs recommended for patients on dialysis. Saxagliptin is known for its potent effect and long duration of action. In this study, we compared the efficacy of Saxagliptin w...

    Authors: Yukinao Sakai, Saori Sakai, Koji Mugishima, Anna Katayama, Yuichiro Sumi, Yusuke Otsuka, Tomoyuki Otsuka and Shuichi Tsuruoka
    Citation: Renal Replacement Therapy 2017 3:15
  23. Insulin antibody appears in approximately 40% of insulin users using human insulin and insulin analog formulations. Insulin antibody, characterized by high affinity and low insulin antibody binding capacity (%...

    Authors: Kentaro Wada, Haruhito A. Uchida and Yuko Wada
    Citation: Renal Replacement Therapy 2017 3:14
  24. Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Most cases of aHUS are caused by u...

    Authors: Yoko Yoshida, Hideki Kato and Masaomi Nangaku
    Citation: Renal Replacement Therapy 2017 3:5
  25. Vascular calcification has now been recognized as a major problem in dialysis patients because of its strong influence on the prognosis. Along with the regulatory failure of calcification-inhibitory system, ac...

    Authors: Takayasu Ohtake and Shuzo Kobayashi
    Citation: Renal Replacement Therapy 2017 3:13
  26. Sepsis is a systemic inflammatory response syndrome caused by infectious disease. Severe sepsis and septic shock are extremely serious conditions with poor prognoses. It is reported that cytokines are deeply i...

    Authors: Akihito Tanaka, Daijo Inaguma, Tomoaki Nakamura, Yu Watanabe, Eri Ito, Naoki Kamegai, Hiroya Shimogushi, Minako Murata, Hibiki Shinjo, Kiyomi Koike, Yasuhiro Otsuka and Asami Takeda
    Citation: Renal Replacement Therapy 2017 3:12
  27. Acute pulmonary edema (APE) has a poor prognosis in the general population. Mortality associated with APE in patients with end-stage renal disease (ESRD) is especially high, although specific predictors are no...

    Authors: Saki Hasegawa, Shintaro Nakano, Jun Tanno, Shiro Iwanaga, Ritsushi Kato, Toshihiro Muramatsu, Yusuke Watanabe, Hirokazu Okada, Takaaki Senbonmatsu, Hidetomo Nakamoto and Shigeyuki Nishimura
    Citation: Renal Replacement Therapy 2017 3:8
  28. The introduction of direct-acting antiviral agents (DAAs) for the treatment of chronic hepatitis C virus (HCV) infection in patients undergoing hemodialysis (HD) has improved sustained virological response (SV...

    Authors: Haruki Uojima, Shuzo Kobayashi, Hisashi Hidaka, Shuichi Matsumoto, Takayasu Ohtake, Takeshi Kinbara, Machiko Oka, Yasuhiro Yamanouchi, Takehiko Kunieda, Hiroki Yamanoue, Takayuki Kanemaru, Kazuhiko Tsutsumi, Tomoaki Fujikawa, Ji Hyun Sung and Makoto Kako
    Citation: Renal Replacement Therapy 2017 3:7
  29. Post-transplant recurrent nephritis is the third common complication that leads to graft loss, which affects the long-term graft survival of kidney transplant patients. Immunoglobulin A nephropathy (IgAN) is t...

    Authors: Hiroshi Nihei, Ken Sakai, Seiichiro Shishido, Kazutoshi Sibuya, Hideo Edamatsu and Atsushi Aikawa
    Citation: Renal Replacement Therapy 2017 3:10
  30. The Japanese Society for Dialysis Therapy (JSDT) has performed a nationwide renal data registry since 1966. The data from the survey have been used for promoting dialysis facilities to improve dialysis quality...

    Authors: Ikuto Masakane, Shigeru Nakai, Satoshi Ogata, Naoki Kimata, Norio Hanafusa, Takayuki Hamano, Kenji Wakai, Atsushi Wada and Kosaku Nitta
    Citation: Renal Replacement Therapy 2017 3:18
  31. Malnutrition-related conditions such as protein energy wasting are affecting poor outcome of the dialysis population. The serum albumin level is often used as a marker of wasting and malnutrition. However, the...

    Authors: Norio Hanafusa, Kosaku Nitta, Masayuki Okazaki, Mizuki Komatsu, Shunji Shiohira, Hiroshi Kawaguchi and Ken Tsuchiya
    Citation: Renal Replacement Therapy 2017 3:9
  32. Improvements in immunosuppression have reduced acute kidney allograft rejection and clinicians are now seeking ways to prolong allograft survival to 20 years and beyond. The primary cause of kidney allograft l...

    Authors: Ai Katsuma, Takafumi Yamakawa, Yasuyuki Nakada, Izumi Yamamoto and Takashi Yokoo
    Citation: Renal Replacement Therapy 2017 3:6
  33. We assessed laboratory data related to mortality in hemodialysis (HD) patients. In our preliminary study, we examined all of the data for HD outpatients in our facility according to whether the patient had sur...

    Authors: Chieko Takagi, Kumeo Ono, Hidenori Matsuo, Nobuo Nagano and Yoshihisa Nojima
    Citation: Renal Replacement Therapy 2017 3:4
  34. The older dialysis population is increasing, and several studies have investigated the effect of actual age on the relationship between clinical parameters or clinical practice and prognosis. There is concern ...

    Authors: Norio Hanafusa, Satoko Sakurai and Masaomi Nangaku
    Citation: Renal Replacement Therapy 2017 3:1
  35. In patients on maintenance dialysis, increased serum calcium levels are known to be associated with a poor prognosis. However, it is not known whether serum calcium levels at dialysis initiation have an impact...

    Authors: Daijo Inaguma, Shigehisa Koide, Kazuo Takahashi, Hiroki Hayashi, Midori Hasegawa and Yukio Yuzawa
    Citation: Renal Replacement Therapy 2017 3:2
  36. Currently, the Asian region is showing marked population growth and economic progress. In developing countries in Asia, rapid demands for dialysis therapy which have the same standard as those delivered in dev...

    Authors: Toru Hyodo, Nobuhito Hirawa, Matsuhiko Hayashi, Khin Maung Maung Than, Do Gia Tuyen, Korntip Pattanasittangkur, Liu Wen Hu, Tomotaka Naramura, Kenichi Miyamoto and Akihiro C. Yamashita
    Citation: Renal Replacement Therapy 2017 3:11
  37. The authors herein report a case of pain, femoral vein thrombosis, and inguinal subcutaneous hematoma caused by percutaneous femoral vascular catheterization in a hemodialysis (HD) patient complicated with vas...

    Authors: Kentaro Wada, Haruhito A. Uchida and Yuko Wada
    Citation: Renal Replacement Therapy 2017 3:3
  38. Fabry disease is a rare X-linked hereditary disorder (Xq22) caused by a deficiency in alpha-galactosidase (α-GAL) activity. This enzyme deficit results in the systemic accumulation of glycophospholipids, leadi...

    Authors: Ayako Saito, Tomoyoshi Kimura, Yoichi Takeuchi, Ken Matsuda, Hirotaka Fukami, Hiroyuki Sato, Yoshitsugu Iwakura, Hiroshi Sato and Tasuku Nagasawa
    Citation: Renal Replacement Therapy 2017 2:69
  39. The influence of prolongation of hemodialysis (HD) period for erectile dysfunction (ED) has not been well evaluated. We evaluated the effects of various factors including hemodialysis duration for ED in hemodi...

    Authors: Hayato Nishida, Atsushi Yamagishi, Toshihiko Sakurai, Tomohiro Shibasaki, Hisashi Kawazoe, Osamu Ichiyanagi, Tomoyuki Kato, Akira Nagaoka, Yoshihiko Tomita and Norihiko Tsuchiya
    Citation: Renal Replacement Therapy 2016 2:65
  40. Peripheral artery disease (PAD) is not only a serious complication but also a risk factor to predict prognosis in the patients with hemodialysis (HD). Ankle-brachial blood pressure index (ABI) has been widely ...

    Authors: Nanami Kida, Shunro Ageta, Yasunori Tsujimoto, Kiyoko Maehara, Masayuki Nagahara, Yoshinosuke Hamada and Nariaki Matsuura
    Citation: Renal Replacement Therapy 2016 2:66
  41. Mineralocorticoid receptor (MR) antagonists are known to have beneficial effects in patients with cardiovascular disease without renal failure. However, there have been few published studies on the effectivene...

    Authors: Mitsuhiro Tawada, Yasuhiro Suzuki, Fumiko Sakata, Masashi Mizuno and Yasuhiko Ito
    Citation: Renal Replacement Therapy 2016 2:64
  42. Therapeutic plasma exchange (TPE) is an important treatment modality for various diseases, but its use can be restricted by allergic reactions (AR). The aim of our study was to elucidate the frequency of and r...

    Authors: Mikako Hisamichi, Hiroo Kawarazaki, Masato Oroku, Kayori Tsuruoka, Tsutomu Sakurada, Sayuri Shirai, Ryo Kido, Kenjiro Kimura and Yugo Shibagaki
    Citation: Renal Replacement Therapy 2016 2:67
  43. Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening complication of heparin anticoagulation. Recently, infection has been implicated in the development of HIT.

    Authors: Sayaka Sugioka, Yohei Doi, Takeshi Ishihara, Tetsuya Arisato, Keisuke Osaki, Kenichi Koga, Masao Koshikawa and Akira Sugawara
    Citation: Renal Replacement Therapy 2016 2:62
  44. The first deceased and living donor kidney transplants were performed in 1956 and 1964 in Japan, respectively. Larger numbers of transplants were performed after the introduction of cyclosporine in 1983. After...

    Authors: Takashi Yagisawa, Makiko Mieno, Norio Yoshimura, Kenji Yuzawa and Shiro Takahara
    Citation: Renal Replacement Therapy 2016 2:68
  45. Renal failure can cause the deterioration of glucose metabolism and increase blood glucose fluctuations, which have been reported to be a factor in the progression of vascular disorders. Little information is ...

    Authors: Naoki Washida, Takahiro Kasai, Kozi Hosoya, Hirobumi Tokuyama, Shu Wakino and Hiroshi Itoh
    Citation: Renal Replacement Therapy 2016 2:57
  46. Perforation of intra-abdominal organs such as the bowel and urinary bladder is one of the most serious complications related to peritoneal dialysis catheter (PDC) insertion procedures. Such a risk increases in...

    Authors: Hiroyuki Terawaki, Naotaro Fukushima, Keiko Aoyagi, Aya Nakajima, Masaaki Nakayama and Tomokazu Karino
    Citation: Renal Replacement Therapy 2016 2:51

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