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  2. Assisted peritoneal dialysis (asPD) is a modality intended for not self-sufficient patients, mainly elderly, who are not able to perform peritoneal dialysis (PD) alone and require some help to manage the treat...

    Authors: Anna Giuliani, Luca Sgarabotto, Sabrina Milan Manani, Ilaria Tantillo, Claudio Ronco and Monica Zanella
    Citation: Renal Replacement Therapy 2022 8:2
    Content type: Review Published on:

  3. Hemodialysis (HD) is a protein catabolic event. However, the amino acid (AA) kinetics during HD sessions involved in protein breakdown have not been well investigated in patients with and without diabetes mell...

    Authors: Masako Fujiwara, Itiro Ando, You Shishido, Yutaka Imai and Hiroyuki Terawaki
    Citation: Renal Replacement Therapy 2022 8:1
    Content type: Case Report Published on:

  4. All-cause mortality can be reduced in patients receiving European-style high-volume post-dilution online hemodiafiltration (post-OHDF) compared with hemodialysis (HD). Japanese-style high-volume pre-dilution o...

    Authors: Kazuyoshi Okada, Hiroyuki Michiwaki, Manabu Tashiro, Tomoko Inoue, Hisato Shima, Jun Minakuchi and Shu Kawashima
    Citation: Renal Replacement Therapy 2021 7:70
    Content type: Research Published on:

  5. End-of-life medical care for patients receiving maintenance hemodialysis (HD) therapy has become an increasingly important issue worldwide. Thus far, no clear indicators and/or biomarkers exist regarding the t...

    Authors: Tadashi Yoshida, Kohkichi Morimoto, Takashin Nakayama, Takuto Torimitsu, Shotaro Kosugi, Takuma Oshida, Nobuko Yamaguchi and Mototsugu Oya
    Citation: Renal Replacement Therapy 2021 7:69
    Content type: Research Published on:

  6. Although not indicated in the USA, edoxaban tosylate hydrate 15 mg is used for venous thromboembolism (VTE) prophylaxis after orthopedic surgery of the lower extremities in Japan. However, its efficacy and saf...

    Authors: Teruhisa Kinoshita, Sayuri Otsuka, Shota Torii, Yoko Tsugeno, Shiori Fukaya, Mari Sobue, Ayumi Ishihara, Takashi Sakakibara and Norio Takimoto
    Citation: Renal Replacement Therapy 2021 7:68
    Content type: Research Published on:

  7. Peripheral artery disease (PAD) is a serious complication in hemodialysis (HD) patients. Low skin perfusion pressure (SPP) is a useful marker for detecting PAD. Malnutrition is an important cause of intractabl...

    Authors: Maho Watanabe, Asami Fuji, Sayuri Tokushima, Keiko Uemoto, Masayo Ueno, Yuko Shimomura, Kenji Ito, Tetsuhiko Yasuno, Kosuke Masutani and Takao Saito
    Citation: Renal Replacement Therapy 2021 7:67
    Content type: Research Published on:

  8. Hyperkalemia is a serious medical condition that requires immediate intervention. However, pseudohyperkalemia and reverse pseudohyperkalemia are misleading clinical manifestations that can result in incorrect ...

    Authors: Muneera Alabdulqader, Hanaa Al Alawyat, Mohammed F. Kasem, Abdelfattah Ibrahim and Abdelwahab Omara
    Citation: Renal Replacement Therapy 2021 7:66
    Content type: Case Report Published on:

  9. The prevalence of end-stage renal disease (ESRD) is on the rise worldwide. Meanwhile, the number of older people requiring dialysis therapy is increasing as a result of this population. We found that starting ...

    Authors: Atthaphong Phongphithakchai, Phongsak Dandecha, Sukit Raksasuk and Thatsaphan Srithongkul
    Citation: Renal Replacement Therapy 2021 7:65
    Content type: Review Published on:

  10. Peritoneal dialysis (PD)-associated peritonitis caused by Sphingomonas paucimobilis (S. paucimobilis) is very rare, and most of the characteristics of such cases are still unknown.

    Authors: Chiharu Kinoshita, Koichi Matsuda, Yumiko Kawai, Takayuki Hagiwara and Akane Okada
    Citation: Renal Replacement Therapy 2021 7:64
    Content type: Case Report Published on:

  11. Hemodialysis (HD) patients are at a high risk of falls and fractures. The amount of physical activity (PA) they perform may be limited by psychosomatic factors associated with fear of falling, leading to frail...

    Authors: Nobuyuki Shirai, Suguru Yamamoto, Yutaka Osawa, Atsuhiro Tsubaki, Shinichiro Morishita, Sumiyo Nitami and Ichiei Narita
    Citation: Renal Replacement Therapy 2021 7:63
    Content type: Research Published on:

  12. Hemodialysis is a medical technology implemented for various renal diseases and has a significant budget impact in Japan. Hemodialysis also affects health-related quality of life, as it interferes with daily l...

    Authors: Shinichi Noto, Masashi Miyazaki, Hidemi Takeuchi and Shinya Saito
    Citation: Renal Replacement Therapy 2021 7:62
    Content type: Research Published on:

  13. The appropriate dosing of imipenem for critically ill AKI patients undergoing CRRT remains scarce.

    Authors: Dhakrit Rungkitwattanakul, Taniya Charoensareerat, Pathakorn Kerdnimith, Nutsinee Kosumwisaisakul, Piyakamol Teeranaew, Apinya Boonpeng, Sutthiporn Pattharachayakul, Nattachai Srisawat and Weerachai Chaijamorn
    Citation: Renal Replacement Therapy 2021 7:61
    Content type: Research Published on:

  14. Removal of anti-blood group antibodies is important for successful ABO-incompatible kidney transplantation (ABOi-KTx). Double-filtration plasmapheresis (DFPP) using albumin solution removes antibodies effectiv...

    Authors: Daiki Iwami, Takenao Matsumoto, Kota Ono, Kiyohiko Hotta, Minoru Ota, Yuki Chiba, Hajime Sasaki, Takayuki Hirose, Haruka Higuchi, Yusuke Takada, Naoya Iwahara, Sachiyo Murai and Nobuo Shinohara
    Citation: Renal Replacement Therapy 2021 7:60
    Content type: Research Published on:

  15. The Japanese Association of Dialysis Physicians, the Japanese Society for Dialysis Therapy, and the Japanese Society of Nephrology jointly established COVID-19 Task Force Committee and began surveying the numb...

    Authors: Kan Kikuchi, Masaomi Nangaku, Munekazu Ryuzaki, Tomoyuki Yamakawa, Oota Yoshihiro, Norio Hanafusa, Ken Sakai, Yoshihiko Kanno, Ryoichi Ando, Toshio Shinoda, Hidetomo Nakamoto and Tadao Akizawa
    Citation: Renal Replacement Therapy 2021 7:59
    Content type: Research Published on:

  16. Enhanced oxidative stress is involved with fatigue in hemodialysis (HD) patients. Molecular hydrogen (H2) could improve the redox status. Thus, the study examines whether HD solution rendered by electrolyzed wate...

    Authors: Yoshihiro Tsujimoto, Daisuke Kuratsune, Shigeru Kabayama, Mariko Miyazaki, Yasuyoshi Watanabe, Yoshiki Nishizawa and Masaaki Nakayama
    Citation: Renal Replacement Therapy 2021 7:58
    Content type: Research Published on:

  17. Though treatment of anemia in chronic kidney disease (CKD) patients has been improved remarkably by erythropoiesis-stimulating agents (ESA), hypo-responsiveness to ESA poses a persistent problem in a subgroup ...

    Authors: Akira Ishimitsu, Hiroshi Satonaka, Masahito Furuichi, Yoshiki Murayama, Akihiro Tojo and Toshihiko Ishimitsu
    Citation: Renal Replacement Therapy 2021 7:57
    Content type: Research Published on:

  18. In Japan, forgoing life-sustaining treatment to respect the will of patients at the terminal stage is not stipulated by law. According to the Guidelines for the Decision-Making Process in Terminal-Stage Health...

    Authors: Kazuyoshi Okada, Ken Tsuchiya, Ken Sakai, Takahiro Kuragano, Akiko Uchida, Kazuhiko Tsuruya, Tadashi Tomo, Chieko Hamada, Masafumi Fukagawa, Yoshindo Kawaguchi, Yuzo Watanabe, Kaoruko Aita, Yoshitatsu Ogawa, Junji Uchino, Hirokazu Okada, Yutaka Koda…
    Citation: Renal Replacement Therapy 2021 7:56
    Content type: Position statement Published on:

  19. The prevalence of chronic kidney disease (CKD) has been on the rise worldwide. Epidemiological studies performed primarily in Central America and South Asia have reported high prevalence of CKD among young and...

    Authors: Kei Nagai
    Citation: Renal Replacement Therapy 2021 7:55
    Content type: Review Published on:

  20. Kidney transplantation has established itself as the most appropriate mode of renal replacement therapy for the majority with end-stage kidney disease. Although at present this is applicable for children as we...

    Authors: Thilina Gunawardena, Hemant Sharma, Ajay Kumar Sharma and Sanjay Mehra
    Citation: Renal Replacement Therapy 2021 7:54
    Content type: Review Published on:

  21. Cambodia detected its first case of COVID-19 just 3 days before WHO declared that the outbreak constituted as PHEIC. As of February 15, 2021, and after two major outbreaks, only 479 cases had been reported, 39...

    Authors: Tam Nov, Toru Hyodo, Yukie Kitajima, Kenichi Kokubo, Toshihide Naganuma, Haruki Wakai, Akihiro Yamashita, Elin Phon and Hideki Kawanishi
    Citation: Renal Replacement Therapy 2021 7:53
    Content type: Review Published on:

  22. Systemic capillary leak syndrome (SCLS) is a rare disorder characterized by hypotension, hemoconcentration, and hypoalbuminemia associated with increased capillary endothelium permeability. Patients with a chr...

    Authors: Keisuke Sunohara, Rie Shimizu, Kazushi Yasuda, Akiko Owaki, Hiroshi Nagaya, Tomohiro Kajiguchi and Shinichiro Inaba
    Citation: Renal Replacement Therapy 2021 7:52
    Content type: Case Report Published on:

  23. Evidence concerning online hemodiafiltration (ol-HDF) includes increased uremic toxin removal, prevention of dialysis-related hypotension, improved survival, and recovery of dialysis-related uncertain symptoms...

    Authors: Hideki Kawanishi
    Citation: Renal Replacement Therapy 2021 7:51
    Content type: Review Published on:

  24. Salazosulfapyridine is a generally safe drug often used to treat rheumatoid arthritis and ulcerative colitis. However, agranulocytosis is a rare but serious adverse effect of this drug. To date, there have bee...

    Authors: Takeshi Iida, Kimihiko Nakata, Masayoshi Fukui and Masaru Umeda
    Citation: Renal Replacement Therapy 2021 7:50
    Content type: Case Report Published on:

  25. In Japan, only less than 3% of patients undergoing maintenance dialysis select peritoneal dialysis (PD) as the mode of renal replacement therapy. Half of patients undergoing PD use a cycler for automated PD (A...

    Authors: Hisako Yoshida and Kazuhiko Tsuruya
    Citation: Renal Replacement Therapy 2021 7:49
    Content type: Research Published on:

  26. Whether progressive mild to moderate aortic stenosis in hemodialysis patients influences their prognosis has not been elucidated. This prospective cohort study explored whether progressive aortic stenosis pred...

    Authors: Yoriko Horiguchi, Kaoru Uemura, Naoyoshi Aoyama, Shinichi Nakajima, Tomoki Asai, Sachiko Motohashi, Manae Harada, Maoko Ida and Atsushi Yoshida
    Citation: Renal Replacement Therapy 2021 7:48
    Content type: Research Published on:

  27. Sepsis is associated with life-threatening organ dysfunction caused by a dysregulated host response to infection. However, no specific therapy has been shown to improve mortality in patients with sepsis. We co...

    Authors: Kasumi Satoh, Kyoko Nomura, Hajime Nakae, Daisuke Kudo, Shigeki Kushimoto, Masatsugu Hasegawa, Fumihito Ito, Satoshi Yamanouchi, Hiroyuki Honda, Kohkichi Andoh, Hajime Furukawa, Yasuo Yamada, Yuta Tsujimoto and Manabu Okuyama
    Citation: Renal Replacement Therapy 2021 7:47
    Content type: Research Published on:

  28. This article is a duplicated publication from the Japanese version of “2019 JSDT Guidelines for Peritoneal Dialysis” with permission from the Japanese Society for Dialysis Therapy (JSDT). This clinical practic...

    Authors: Munekazu Ryuzaki, Yasuhiko Ito, Hidetomo Nakamoto, Yuichi Ishikawa, Noritomo Itami, Minoru Ito, Atsushi Ueda, Yoshie Kanazawa, Hideki Kawanishi, Yoshihiko Kanno, Hitoshi Sugiyama, Kazuhiko Tsuruya, Hiroyuki Terawaki, Tadashi Tomo, Mizuya Fukasawa, Akihiro C. Yamashita…
    Citation: Renal Replacement Therapy 2021 7:46
    Content type: Position statement Published on:

  29. Vitamin D deficiency is often observed in patients undergoing maintenance hemodialysis and is associated with significantly increased risk of overall mortality. Despite reports of poor nutrition/intake, vitami...

    Authors: Keisuke Yoshida, Tomoki Yonaha, Masayuki Yamanouchi, Hirofumi Sumi, Yasuhiro Taki, Yuhei Otobe, Minoru Miyashita, Rina Hachisuka, Wei Han, Yugo Shibagaki and Naoto Tominaga
    Citation: Renal Replacement Therapy 2021 7:45
    Content type: Research Published on:

  30. Whether uric acid (UA)-lowering therapy (ULT) is effective in reducing the progression of renal dysfunction in patients with chronic kidney disease (CKD) remains controversial. Since several advances have been...

    Authors: Yukio Maruyama, Takanori Kumagai, Naoki Sugano, Shigetaka Yoshida, Kimiyoshi Ichida and Shunya Uchida
    Citation: Renal Replacement Therapy 2021 7:44
    Content type: Research Published on:

  31. In May and June 2020, an outbreak of methanol poisoning arose in the southwest United States linked to ingestion of contaminated hand sanitizer imported during the coronavirus disease 2019 pandemic, ultimately...

    Authors: Alisa C. Illescas, Christos P. Argyropoulos, Sara A. Combs, Saeed K. Shaffi, Zhi Q. Xu, Michael A. Aragon and J. Pedro Teixeira
    Citation: Renal Replacement Therapy 2021 7:43
    Content type: Case Report Published on:

  33. According to the annual survey of the Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) conducted at the end of 2018, there were a total of 339,841 patients receiving dialysis (hereinafter, dial...

    Authors: Kosaku Nitta, Shigeru Nakai, Ikuto Masakane, Norio Hanafusa, Shunsuke Goto, Masatomo Taniguchi, Takeshi Hasegawa, Atsushi Wada, Takayuki Hamano, Junichi Hoshino, Nobuhiko Joki, Keichi Yamamoto, Kenichiro Miura, Masanori Abe and Hidetomo Nakamoto
    Citation: Renal Replacement Therapy 2021 7:41
    Content type: Position statement Published on:

  34. Approximately 10 years have passed since the Peritoneal Dialysis Guidelines were formulated in 2009. Much evidence has been reported during the succeeding years, which were not taken into consideration in the ...

    Authors: Yasuhiko Ito, Munekazu Ryuzaki, Hitoshi Sugiyama, Tadashi Tomo, Akihiro C. Yamashita, Yuichi Ishikawa, Atsushi Ueda, Yoshie Kanazawa, Yoshihiko Kanno, Noritomo Itami, Minoru Ito, Hideki Kawanishi, Masaaki Nakayama, Kazuhiko Tsuruya, Hideki Yokoi, Mizuya Fukasawa…
    Citation: Renal Replacement Therapy 2021 7:40
    Content type: Position statement Published on:

  35. The Japanese population is aging quickly. New methods of supporting peritoneal dialysis (PD) for elderly patients are essential if we are to increase the number of such patients.

    Authors: Kohsuke Terada, Yorito Yanagida, Tomohiro Yan, Toshiki Funakoshi, Akio Hirama, Tetsuya Kashiwagi and Yukinao Sakai
    Citation: Renal Replacement Therapy 2021 7:39
    Content type: Research Published on:

  37. A novel hemodialysis (HD) system employing electrolyzed water containing molecular hydrogen (E-HD) has been developed to improve the bio-compatibility of HD. This study examined the impact of E-HD on changes i...

    Authors: Hidehisa Satta, Tamio Iwamoto, Yuki Kawai, Naoaki Koguchi, Kazuhiko Shibata, Nobuteru Kobayashi, Mariko Yoshida and Masaaki Nakayama
    Citation: Renal Replacement Therapy 2021 7:37
    Content type: Research Published on:

  39. Low physical fitness is often found in patients undergoing hemodialysis. It may be possible that the recovery of impaired motor function with rehabilitative training might be affected when the patient is on he...

    Authors: Takeki Ishida, Kenichi Kono, Yuusuke Nishida and Masahiro Yoshida
    Citation: Renal Replacement Therapy 2021 7:35
    Content type: Research Published on:

  40. The risk of adverse events associated with peritoneal dialysis (PD) in elderly patients has not been thoroughly investigated. The purpose of this study was to assess the association between physical function a...

    Authors: Hiroki Yabe, Yuto Imoto, Ayaka Onoyama, Sayaka Ito, Kenichi Kono, Yoshifumi Moriyama, Keiko Okada, Hirotake Kasuga and Yasuhiko Ito
    Citation: Renal Replacement Therapy 2021 7:34
    Content type: Research Published on:

  41. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect the kidney and the presence of chronic kidney disease (CKD) constitutes a higher risk of negative prognosis. SARS-CoV-2 main sequelae in ...

    Authors: Heitor S. Ribeiro, Amanda E. Rodrigues, Jennifer Cantuária, Antônio Inda-Filho and Paul N. Bennett
    Citation: Renal Replacement Therapy 2021 7:33
    Content type: Review Published on:

  42. Despite the fact that the fundamental characteristics of coronavirus disease-2019 (COVID-19) are respiratory manifestations, multi-organ failure including the kidney has been documented. There are no clear com...

    Authors: Enass E. El-Sayed, Abdou K. Allayeh, Amany A. Salem, Sheren M. Omar, Salwa M. Zaghlol, Hala M. Abd-Elmaguid, Mohammed M. Abdul-Ghaffar and Magdy M. ElSharkawy
    Citation: Renal Replacement Therapy 2021 7:32
    Content type: Research Published on:

  43. Malnutrition that is associated with inflammation is a key factor of poor outcome in chronic hemodialysis patients, especially in older dialysis patients. Polymethyl methacrylate (PMMA) membrane has been repor...

    Authors: Ikuto Masakane, Ichiro Yamaguchi, Yuji Matsumoto, Ken Ataka, Yuta Oyama, Michio Nagaoka, Yasushi Matsushita, Tomoko Teramura, Koji Seino, Hiroyuki Amano and Ai Kobayashi
    Citation: Renal Replacement Therapy 2021 7:31
    Content type: Research Published on:

  44. Patients with chronic kidney disease often suffer from cardiovascular disease, and vascular calcification has been identified as one of the risk factors for cardiovascular disease. We aimed to examine the effe...

    Authors: Kentaro Nakai, Shutaro Yamamoto, Megumi Inoue, Chiaki Kohara, Tomoya Shukuri, Kentaro Motoyama and Koji Mitsuiki
    Citation: Renal Replacement Therapy 2021 7:30
    Content type: Research Published on:

  45. In order to facilitate the safe and long-term delivery of peritoneal dialysis (PD), it is necessary to improve the biocompatibility of peritoneal dialysis fluids (PDFs). The novel bicarbonate/lactate-buffered ...

    Authors: Hiromichi Ueno, Tetsu Miyamoto, Hiroyuki Morimoto, Kenya Sanada, Ikutaro Furuno, Kazutoshi Nakazono, Emi Hasegawa, Akihiro Kuma, Yasushi Oginosawa, Yuki Tsuda, Masaru Araki, Masahito Tamura, Yoichi Ueta, Yutaka Otsuji and Masaharu Kataoka
    Citation: Renal Replacement Therapy 2021 7:29
    Content type: Research Published on:

  46. The prevalence of end-stage kidney disease (ESKD) is growing worldwide; the survival of these patients requires renal replacement therapy (RRT, a complex and costly treatment). Over 20% of the patients that st...

    Authors: Isabella Vanorio-Vega, Panayotis Constantinou, Philippe Tuppin and Cécile Couchoud
    Citation: Renal Replacement Therapy 2021 7:28
    Content type: Review Published on:

  47. Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic affecting a variety of medical treatments, including hemodialysis. This...

    Authors: Yuka Sugawara, Masao Iwagami, Kan Kikuchi, Yoko Yoshida, Ryoichi Ando, Toshio Shinoda, Munekazu Ryuzaki, Hidetomo Nakamoto, Ken Sakai, Norio Hanafusa, Naoki Kashihara and Masaomi Nangaku
    Citation: Renal Replacement Therapy 2021 7:27
    Content type: Position statement Published on:

  48. Low-ionized magnesium and high-ionized calcium levels are associated with increased cardiovascular mortality in patients undergoing dialysis. We examined the effects of the dilution method, substitution volume...

    Authors: Yusaku Tanaka, Hisato Shima, Ryosuke Hatonari, Daisuke Okada, Hiroyuki Michiwaki, Seiichiro Wariishi, Tomohiro Tao and Jun Minakuchi
    Citation: Renal Replacement Therapy 2021 7:26
    Content type: Research Published on:

  49. Peritoneal dialysis (PD)-related peritonitis risk factors can be categorized as modifiable and uncorrectable. We aimed to identify modifiable risk factors for PD-related peritonitis in our facility to prevent ...

    Authors: Shigeki Kojima, Shohei Yamada, Rie Fujishima, Kenichiro Koitabashi, Yugo Shibagaki and Tsutomu Sakurada
    Citation: Renal Replacement Therapy 2021 7:25
    Content type: Research Published on:

  50. Hemodialysis-associated pruritus (HAP) is a serious complication that occurs in 60–80% of hemodialysis patients, which not only decreases quality of life but also worsens prognosis. We have developed a treatme...

    Authors: Naoko Takahashi, Taku Yoshizawa, Junko Kumagai, Hideki Kawanishi, Shinichiro Tsuchiya, Misaki Moriishi and Takao Masaki
    Citation: Renal Replacement Therapy 2021 7:24
    Content type: Research Published on:
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Renal Replacement Therapy

ISSN: 2059-1381

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