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Table 5 Proposal for discontinuation of combined therapy with PD and HD

From: Clinical efficacy of combined therapy with peritoneal dialysis and hemodialysis

1. Insufficient solute removal (inadequate dialysis)

 β2 microglobulin >35 mg/L

 Other uremic symptoms

  Deterioration of nutritional status, decreased SGA, persistent anorexia

  ESA-hyporesponsive anemia

  Restless legs syndrome

2. Insufficient fluid removal (fluid overload)

 Higher or drug-resistant blood pressure

 Heart enlargement or pleural effusion on chest X-rays

 Persistent peripheral edema, anasarca

3. Consideration of the risk of development of EPS

 Prolonged PD duration

 Frequent PD-associated peritonitis

 Higher D/P Cr

  1. PD peritoneal dialysis, HD hemodialysis, SGA subjective global assessment, ESA erythropoiesis-stimulating agent, EPS encapsulating peritoneal sclerosis, D/P Cr dialysate-to-plasma ratio of creatinine