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  1. According to the annual survey of the Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) conducted at the end of 2018, there were a total of 339,841 patients receiving dialysis (hereinafter, dial...

    Authors: Kosaku Nitta, Shigeru Nakai, Ikuto Masakane, Norio Hanafusa, Shunsuke Goto, Masatomo Taniguchi, Takeshi Hasegawa, Atsushi Wada, Takayuki Hamano, Junichi Hoshino, Nobuhiko Joki, Keichi Yamamoto, Kenichiro Miura, Masanori Abe and Hidetomo Nakamoto

    Citation: Renal Replacement Therapy 2021 7:41

    Content type: Position statement

    Published on:

  2. Approximately 10 years have passed since the Peritoneal Dialysis Guidelines were formulated in 2009. Much evidence has been reported during the succeeding years, which were not taken into consideration in the ...

    Authors: Yasuhiko Ito, Munekazu Ryuzaki, Hitoshi Sugiyama, Tadashi Tomo, Akihiro C. Yamashita, Yuichi Ishikawa, Atsushi Ueda, Yoshie Kanazawa, Yoshihiko Kanno, Noritomo Itami, Minoru Ito, Hideki Kawanishi, Masaaki Nakayama, Kazuhiko Tsuruya, Hideki Yokoi, Mizuya Fukasawa…

    Citation: Renal Replacement Therapy 2021 7:40

    Content type: Position statement

    Published on:

  3. The Japanese population is aging quickly. New methods of supporting peritoneal dialysis (PD) for elderly patients are essential if we are to increase the number of such patients.

    Authors: Kohsuke Terada, Yorito Yanagida, Tomohiro Yan, Toshiki Funakoshi, Akio Hirama, Tetsuya Kashiwagi and Yukinao Sakai

    Citation: Renal Replacement Therapy 2021 7:39

    Content type: Research

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  4. A novel hemodialysis (HD) system employing electrolyzed water containing molecular hydrogen (E-HD) has been developed to improve the bio-compatibility of HD. This study examined the impact of E-HD on changes i...

    Authors: Hidehisa Satta, Tamio Iwamoto, Yuki Kawai, Naoaki Koguchi, Kazuhiko Shibata, Nobuteru Kobayashi, Mariko Yoshida and Masaaki Nakayama

    Citation: Renal Replacement Therapy 2021 7:37

    Content type: Research

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  5. Low physical fitness is often found in patients undergoing hemodialysis. It may be possible that the recovery of impaired motor function with rehabilitative training might be affected when the patient is on he...

    Authors: Takeki Ishida, Kenichi Kono, Yuusuke Nishida and Masahiro Yoshida

    Citation: Renal Replacement Therapy 2021 7:35

    Content type: Research

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  6. The risk of adverse events associated with peritoneal dialysis (PD) in elderly patients has not been thoroughly investigated. The purpose of this study was to assess the association between physical function a...

    Authors: Hiroki Yabe, Yuto Imoto, Ayaka Onoyama, Sayaka Ito, Kenichi Kono, Yoshifumi Moriyama, Keiko Okada, Hirotake Kasuga and Yasuhiko Ito

    Citation: Renal Replacement Therapy 2021 7:34

    Content type: Research

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  7. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect the kidney and the presence of chronic kidney disease (CKD) constitutes a higher risk of negative prognosis. SARS-CoV-2 main sequelae in ...

    Authors: Heitor S. Ribeiro, Amanda E. Rodrigues, Jennifer Cantuária, Antônio Inda-Filho and Paul N. Bennett

    Citation: Renal Replacement Therapy 2021 7:33

    Content type: Review

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  8. Despite the fact that the fundamental characteristics of coronavirus disease-2019 (COVID-19) are respiratory manifestations, multi-organ failure including the kidney has been documented. There are no clear com...

    Authors: Enass E. El-Sayed, Abdou K. Allayeh, Amany A. Salem, Sheren M. Omar, Salwa M. Zaghlol, Hala M. Abd-Elmaguid, Mohammed M. Abdul-Ghaffar and Magdy M. ElSharkawy

    Citation: Renal Replacement Therapy 2021 7:32

    Content type: Research

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  9. Malnutrition that is associated with inflammation is a key factor of poor outcome in chronic hemodialysis patients, especially in older dialysis patients. Polymethyl methacrylate (PMMA) membrane has been repor...

    Authors: Ikuto Masakane, Ichiro Yamaguchi, Yuji Matsumoto, Ken Ataka, Yuta Oyama, Michio Nagaoka, Yasushi Matsushita, Tomoko Teramura, Koji Seino, Hiroyuki Amano and Ai Kobayashi

    Citation: Renal Replacement Therapy 2021 7:31

    Content type: Research

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  10. Patients with chronic kidney disease often suffer from cardiovascular disease, and vascular calcification has been identified as one of the risk factors for cardiovascular disease. We aimed to examine the effe...

    Authors: Kentaro Nakai, Shutaro Yamamoto, Megumi Inoue, Chiaki Kohara, Tomoya Shukuri, Kentaro Motoyama and Koji Mitsuiki

    Citation: Renal Replacement Therapy 2021 7:30

    Content type: Research

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  11. In order to facilitate the safe and long-term delivery of peritoneal dialysis (PD), it is necessary to improve the biocompatibility of peritoneal dialysis fluids (PDFs). The novel bicarbonate/lactate-buffered ...

    Authors: Hiromichi Ueno, Tetsu Miyamoto, Hiroyuki Morimoto, Kenya Sanada, Ikutaro Furuno, Kazutoshi Nakazono, Emi Hasegawa, Akihiro Kuma, Yasushi Oginosawa, Yuki Tsuda, Masaru Araki, Masahito Tamura, Yoichi Ueta, Yutaka Otsuji and Masaharu Kataoka

    Citation: Renal Replacement Therapy 2021 7:29

    Content type: Research

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  12. The prevalence of end-stage kidney disease (ESKD) is growing worldwide; the survival of these patients requires renal replacement therapy (RRT, a complex and costly treatment). Over 20% of the patients that st...

    Authors: Isabella Vanorio-Vega, Panayotis Constantinou, Philippe Tuppin and Cécile Couchoud

    Citation: Renal Replacement Therapy 2021 7:28

    Content type: Review

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  13. Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic affecting a variety of medical treatments, including hemodialysis. This...

    Authors: Yuka Sugawara, Masao Iwagami, Kan Kikuchi, Yoko Yoshida, Ryoichi Ando, Toshio Shinoda, Munekazu Ryuzaki, Hidetomo Nakamoto, Ken Sakai, Norio Hanafusa, Naoki Kashihara and Masaomi Nangaku

    Citation: Renal Replacement Therapy 2021 7:27

    Content type: Position statement

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  14. Low-ionized magnesium and high-ionized calcium levels are associated with increased cardiovascular mortality in patients undergoing dialysis. We examined the effects of the dilution method, substitution volume...

    Authors: Yusaku Tanaka, Hisato Shima, Ryosuke Hatonari, Daisuke Okada, Hiroyuki Michiwaki, Seiichiro Wariishi, Tomohiro Tao and Jun Minakuchi

    Citation: Renal Replacement Therapy 2021 7:26

    Content type: Research

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  15. Peritoneal dialysis (PD)-related peritonitis risk factors can be categorized as modifiable and uncorrectable. We aimed to identify modifiable risk factors for PD-related peritonitis in our facility to prevent ...

    Authors: Shigeki Kojima, Shohei Yamada, Rie Fujishima, Kenichiro Koitabashi, Yugo Shibagaki and Tsutomu Sakurada

    Citation: Renal Replacement Therapy 2021 7:25

    Content type: Research

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  16. Hemodialysis-associated pruritus (HAP) is a serious complication that occurs in 60–80% of hemodialysis patients, which not only decreases quality of life but also worsens prognosis. We have developed a treatme...

    Authors: Naoko Takahashi, Taku Yoshizawa, Junko Kumagai, Hideki Kawanishi, Shinichiro Tsuchiya, Misaki Moriishi and Takao Masaki

    Citation: Renal Replacement Therapy 2021 7:24

    Content type: Research

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  17. According to the annual survey of the Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) conducted at the end of 2018, a total of 339,841 patients were receiving dialysis (hereinafter, dialysis p...

    Authors: Kosaku Nitta, Shigeru Nakai, Ikuto Masakane, Norio Hanafusa, Shunsuke Goto, Masatomo Taniguchi, Takeshi Hasegawa, Atsushi Wada, Takayuki Hamano, Junichi Hoshino, Nobuhiko Joki, Keichi Yamamoto, Kenichiro Miura, Masanori Abe and Hidetomo Nakamoto

    Citation: Renal Replacement Therapy 2021 7:22

    Content type: Research

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  18. Intradialytic exercises are recommended to be available as a treatment for enhancing physical functioning. However, there have been few reports which evaluated the results of long-term mild intradialytic exerc...

    Authors: Masahiro Kato, Masanori Shibata, Kazuaki Asai, Kumi Harada, Isao Ito, Hisae Tawada, Kojiro Nagai and Shinkichi Taniguchi

    Citation: Renal Replacement Therapy 2021 7:21

    Content type: Research

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  19. In the development of medical devices usability is an important aspect standing alongside performance and safety. Peritoneal dialysis (PD) can be provided by use of automated PD (APD), assisted by a cycler per...

    Authors: Thore Reitz, Stephanie Schwenke, Sebastian Hölzle and Adelheid Gauly

    Citation: Renal Replacement Therapy 2021 7:20

    Content type: Research

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  20. During the outbreak of new coronavirus pneumonia, many hospitals in China became the designated hospitals for the treatment of new coronavirus pneumonia. The goal was to develop rapid and effective prevention ...

    Authors: Jinmei Yin, Jun Yin, Zhiwu Tian, Peiqiu Li and Xiaoqiu Chen

    Citation: Renal Replacement Therapy 2021 7:19

    Content type: Research

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  21. Intradialytic hypotension (IDH) is one of the most frequent complications of hemodialysis. IDH alters a patient’s quality of life and has a strong association with mortality. IDH mainly occurs when ultrafiltra...

    Authors: Yumi Aoyama, Katsuya Kajimoto, Maiko Hori, Shigeru Otsubo and Kosaku Nitta

    Citation: Renal Replacement Therapy 2021 7:18

    Content type: Research

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  22. Adrenal insufficiency causes abnormal subjective symptoms such as general fatigue, signs such as hypotension, and abnormalities such as hypoglycemia and leads to poor prognosis. However, all these are also obs...

    Authors: Naro Ohashi, Yukitoshi Sakao, Taichi Sato, Sayaka Ishigaki, Shinsuke Isobe, Tomoyuki Fujikura, Akihiko Kato and Hideo Yasuda

    Citation: Renal Replacement Therapy 2021 7:17

    Content type: Research

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  23. Some types of antihypertensive drugs may have pleiotropic effects in patients with chronic kidney disease (CKD). However, whether triple combination therapy with angiotensin II receptor blockers (ARBs), calciu...

    Authors: Sakuya Ito, Yosuke Nakayama, Goh Kodama, Kanji Ota, Kensei Taguchi, Yusuke Kaida, Sho-ichi Yamagishi and Kei Fukami

    Citation: Renal Replacement Therapy 2021 7:16

    Content type: Research

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  24. Multiple organ dysfunction syndrome is the leading cause of death in pediatric intensive care units and can be very critical when combined with shock and disseminated intravascular coagulation (DIC). Currently...

    Authors: Hiroyuki Nagafuchi, Hiroyuki Shimizu, Kaori Yamada, Kenta Shono and Tetsuya Ogawa

    Citation: Renal Replacement Therapy 2021 7:15

    Content type: Research

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  25. More than three hundred thousand hemodialysis (HD) patients exist in Japan. The average of vintage of Japanese hemodialysis patients was longer than Western country. Longer and older hemodialysis patients tend...

    Authors: Takeshi Nakata, Hirotaka Shibata, Yuji Kamijo and Tsuneo Konta

    Citation: Renal Replacement Therapy 2021 7:14

    Content type: Research

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  26. Responsiveness to erythropoiesis-stimulating agents (ESAs) is thought to be related to prognosis in patients on hemodialysis. A multi-center, prospective cohort study was conducted to investigate the effects o...

    Authors: Kenichi Tanaka, Momoko Fujiwara, Hirotaka Saito, Tsuyoshi Iwasaki, Akira Oda, Shuhei Watanabe, Makoto Kanno, Hiroshi Kimura, Yoshihiro Tani, Jun Asai, Hodaka Suzuki, Keiji Sato and Junichiro James Kazama

    Citation: Renal Replacement Therapy 2021 7:13

    Content type: Research

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  27. The impact of end-stage renal disease on the patient’s psychological status necessitates the value of increasing depression awareness. The current study aimed to assess the depression prevalence among Palestin...

    Authors: Samah W. Al-Jabi, Ansam Sous, Fatimah Jorf, Mahmoud Taqatqa, Mahdi Allan, Lamees Sawalha, Enas Lubadeh, Waleed M. Sweileh and Sa’ed H. Zyoud

    Citation: Renal Replacement Therapy 2021 7:12

    Content type: Research

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  28. Online hemodiafiltration (OL-HDF), whether in pre-dilution OL-HDF (pre-HDF) or post-dilution OL-HDF (post-HDF), is conducted to efficiently remove low molecular weight proteins from the blood of patients requi...

    Authors: Kenji Sakurai, Hiromi Hosoya, Yoshitaka Kurihara and Takeshi Saito

    Citation: Renal Replacement Therapy 2021 7:10

    Content type: Research

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  29. To manage the anemic status in hemodialysis (HD) patients, a well-balanced combination therapy based on the use of erythropoiesis-stimulating agents (ESAs) and iron supplementation is essential. Serum ferritin...

    Authors: Kumiko Onda, Teruo Koyama, Sanae Kobayashi, Yoji Ishii and Kazuo Ohashi

    Citation: Renal Replacement Therapy 2021 7:9

    Content type: Research

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  30. In continuous renal replacement therapy (CRRT), administration of anticoagulants is necessary for achieving a certain level of filter lifetime. Generally, anticoagulant doses are controlled to keep activated p...

    Authors: Hiroko Yuzawa, Yousuke Hirose, Tomonori Kimura, Keisuke Shinozaki, Moe Oguchi, Tomohiro Morito and Tomohito Sadahiro

    Citation: Renal Replacement Therapy 2021 7:7

    Content type: Research

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  31. Dialysis patients have to take many oral drugs, causing a high pill burden. Phosphate binders (PBs) account for a large proportion of daily pill burden; however, the relationship between patient background and...

    Authors: Nobuo Nagano, Kyoko Ito, Takashi Ono, Yuichi Ariyoshi, Soichiro Masima, Hajime Kobayashi, Tetsuo Ando, Takaaki Tsutsui and Tetsuya Ogawa

    Citation: Renal Replacement Therapy 2021 7:5

    Content type: Research

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  32. Quality of life for haemodialysis (HD) patients may be affected by symptoms during dialysis treatments, and patient groups have highlighted the need to improve post-dialysis fatigue and dialysis-related sympto...

    Authors: Suree Yoowannakul, Surachet Vongsanim, Kamonwan Tangvoraphonkchai, Ahmed Mohamed and Andrew Davenport

    Citation: Renal Replacement Therapy 2021 7:4

    Content type: Research

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  33. Renal anemia is the important complication in patients undergoing peritoneal dialysis (PD), and heart failure (HF) is the important complication in patients on dialysis. Decreasing endogenous erythropoietin (E...

    Authors: Kohsuke Terada, Yuichiro Sumi, Sae Aratani, Akio Hirama, Tetsuya Kashiwagi and Yukinao Sakai

    Citation: Renal Replacement Therapy 2021 7:3

    Content type: Research

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  34. Creating permanent vascular access (VA) is recommended before hemodialysis initiation in patients with end-stage renal disease (ESRD). Although many patients are still introduced to hemodialysis with temporary...

    Authors: Izaya Nakaya, Taijiro Goto, Yuki Nakamura, Kazuhiro Yoshikawa, Junji Oyama, Yoshihiko Tamayama, Mizuho Morooka, Sadatoshi Ito, Hirotaka Ishioka, Yuki Matsuura and Jun Soma

    Citation: Renal Replacement Therapy 2021 7:2

    Content type: Research

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  35. Clinical studies of anti-glomerular basement membrane (GBM) disease were limited because of the low incidence. We aimed to report the characteristics, treatments, and outcomes of patients with anti-GBM disease...

    Authors: Yoshinosuke Shimamura, Takuto Maeda, Koki Abe, Yayoi Ogawa and Hideki Takizawa

    Citation: Renal Replacement Therapy 2021 7:1

    Content type: Case Report

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  36. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ryoichi Maenosono, Masayoshi Okumi, Kohei Unagami, Hironori Fukuda, Kazuhiko Yoshida, Yoichi Kakuta, Toshio Takagi, Junpei Iizuka, Tomokazu Shimizu, Haruhito Azuma, Yoji Nagashima, Kazunari Tanabe, Kosaku Nitta and Hideki Ishida

    Citation: Renal Replacement Therapy 2020 6:67

    Content type: Correction

    Published on:

    The original article was published in Renal Replacement Therapy 2020 6:52

  37. With the increasing prevalence and incidence of chronic renal failure leading to advanced kidney disease (ESRD), the use of renal transplant therapy is increasing globally. The aim of this study was to determi...

    Authors: Arghavan Malekshahi, Hamidreza Fallah MortezaNejad, Morteza Rahbar Taromsari, Reza Ghanei Gheshlagh and Kourosh Delpasand

    Citation: Renal Replacement Therapy 2020 6:66

    Content type: Research

    Published on:

  38. Since 2015, the Committee of International Communication on Academic Research of the Japanese Society for Dialysis Therapy has held its Asian symposium during the society’s Annual Congress to discuss the prese...

    Authors: Toru Hyodo, Masafumi Fukagawa, Nobuhito Hirawa, Yoshitaka Isaka, Hidetomo Nakamoto, Pham Van Bui, Khin Thida Thwin and Chanseila Hy

    Citation: Renal Replacement Therapy 2020 6:65

    Content type: Review

    Published on:

  39. Etelcalcetide is the first intravenously administered calcimimetic agent used to manage secondary hyperparathyroidism (SHPT) in hemodialysis (HD) patients. We evaluated the safety and efficacy of replacing cin...

    Authors: Yuka Kurokawa, Yusuke Kaida, Takuma Hazama, Yosuke Nakayama, Takaomi Otome, Ryo Shibata, Sakuya Ito, Goh Kodama, Nao Nakamura, Takatoshi Kambe, Tomofumi Moriyama, Akiko Nagata, Aki Minami, Ryotaro Ando, Yoshifumi Wada, Miki Sugiyama…

    Citation: Renal Replacement Therapy 2020 6:64

    Content type: Research

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  40. Gastroparesis is frequently overlooked and difficult to treat. The diagnosis of gastroparesis requires standard upper gastrointestinal endoscopy to exclude gastric outlet obstruction and objective evidence dem...

    Authors: Eriko Eguchi

    Citation: Renal Replacement Therapy 2020 6:62

    Content type: Case Report

    Published on:

  41. There is a higher frequency of advanced chronic kidney disease (CKD) in frail patients than in the general population. This study evaluated frailty status before initiation of dialysis and clarified the progno...

    Authors: Masaki Yoshida, Yurie Takanashi, Takako Harigai, Noriyuki Sakurai, Keiko Kobatake, Hiroaki Yoshida, Satsuki Kobayashi, Takayuki Matsumoto and Kazue Ueki

    Citation: Renal Replacement Therapy 2020 6:60

    Content type: Research

    Published on:

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