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  1. Hypokalemia is common in patients with malnutrition undergoing hemodialysis and is often involved in the development of lethal arrhythmia. Moreover, hemodialysis therapy decreases the serum potassium concentra...

    Authors: Takayuki Uchida, Susumu Ookawara, Kiyonori Ito, Hitomi Okada, Hideyuki Hayasaka, Masaya Kofuji, Masahiko Kimura, Yuichiro Ueda, Tadashi Hasebe, Naoki Momose and Yoshiyuki Morishita
    Citation: Renal Replacement Therapy 2022 8:20
  2. Although recently strengthened immunosuppression protocols have decreased the incidence of clinical acute rejection of renal transplants, subclinical acute rejection and borderline changes remain problematic. ...

    Authors: Kei Sakurabayashi, Masaki Muramatsu, Yoshihiro Itabashi, Hideyo Oguchi, Takeshi Kawamura, Yuko Hamasaki, Tetsuo Mikami, Naobumi Tochigi, Seiichiro Shishido and Ken Sakai
    Citation: Renal Replacement Therapy 2022 8:19
  3. Patients with coronavirus disease 2019 (COVID-19) who receive dialysis therapy develop more severe disease and have a poorer prognosis than patients who do not. Although various data on the treatment of patien...

    Authors: Ayumi Yoshifuji, Munekazu Ryuzaki, Yuki Uehara, Norio Ohmagari, Toru Kawai, Yoshihiko Kanno, Kan Kikuchi, Hiroshi Kon, Ken Sakai, Toshio Shinoda, Yaoko Takano, Junko Tanaka, Kazuhiko Hora, Yasushi Nakazawa, Naoki Hasegawa, Norio Hanafusa…
    Citation: Renal Replacement Therapy 2022 8:18
  4. Acute pericarditis causes acute inflammation of the pericardium. Although most cases of pericarditis are idiopathic with no identifiable cause, its etiology can be infectious, such as viral, bacterial, mycotic...

    Authors: Masahiro Egawa, Shungo Fujii, Kentaro Takase, Ryuichi Yoshimura, Asuka Yamauchi, Kaori Yoshikane, Kazuaki Tanabe, Hiroaki Shiina and Takafumi Ito
    Citation: Renal Replacement Therapy 2022 8:17
  5. Management of presenteeism in the context of chronic kidney disease (CKD) is essential for disease management, ensuring the workforce’s availability, and reducing health-related costs. The purpose of this case...

    Authors: Aki Tabata, Hiroki Yabe, Takehide Katogi, Tomoya Yamaguchi, Yuya Mitake, Tomohiro Shirai and Takayuki Fujii
    Citation: Renal Replacement Therapy 2022 8:16
  6. Although atypical hemolytic uremic syndrome (aHUS) is a life-threatening clinical entity that was characterized by thrombotic microangiopathy (TMA) with the activation of the complement system and the efficien...

    Authors: Noriaki Kawano, Tomohiro Abe, Naoko Ikeda, Yuri Nagahiro, Sayaka Kawano, Taro Tochigi, Takashi Nakaike, Kiyoshi Yamashita, Keisuke Kubo, Atsushi Yamanaka, Sohshi Terasaka, Kousuke Marutsuka, Koichi Mashiba, Ikuo Kikuchi, Kazuya Shimoda, Masanori Matsumoto…
    Citation: Renal Replacement Therapy 2022 8:15
  7. The mortality rate of novel coronaviral disease (COVID-19) patients undergoing dialysis is considerably higher than that of patients with normal kidney function. As of August 2021, only remdesivir has been app...

    Authors: Jun Ito, Moritsugu Kimura, Tomoyuki Toya, Konomi Isozumi, Atsuro Kawaji, Yudai Isozaki and Masafumi Fukagawa
    Citation: Renal Replacement Therapy 2022 8:14
  8. Currently, it is unclear whether the progression of chronic kidney disease (CKD) could be an independent predictor of antibody response after administration of a COVID-19 vaccine. This study aimed to investiga...

    Authors: Masatoshi Matsunami, Tomo Suzuki, Junko Fukuda, Toshiki Terao, Kohei Ukai, Shinnosuke Sugihara, Takumi Toishi, Kanako Nagaoka, Mayumi Nakata, Mamiko Ohara, Jun Yashima, Hiroshi Kuji and Kosei Matsue
    Citation: Renal Replacement Therapy 2022 8:13
  9. In a previous study, patients who underwent unplanned hemodialysis initiation did not have improved nutritional status and activities of daily living (ADL) at discharge compared with patients whose initiation ...

    Authors: Tomoko Yoshida, Togo Aoyama, Yuko Morioka and Yasuo Takeuchi
    Citation: Renal Replacement Therapy 2022 8:12
  10. We previously reported the nutritional advantage of polymethylmethacrylate (PMMA) membranes to prevent the progression of malnutrition in dialysis patients. In this study, we examined whether a new PMMA dialyz...

    Authors: Tetsuro Chida, Hiroyuki Igarashi and Ikuto Masakane
    Citation: Renal Replacement Therapy 2022 8:11
  11. The clinical significance of de novo donor-specific antigen (DSA) in renal transplant recipients is not yet fully understood. This study aimed to report the prevalence of de novo DSA detected in antihuman leuk...

    Authors: Kenji Nakamura, Atsuro Sawada, Yuki Kita, Jin Kono, Kimihiko Masui, Takuma Sato, Takeshi Sano, Takayuki Goto, Shusuke Akamatsu, Osamu Ogawa and Takashi Kobayashi
    Citation: Renal Replacement Therapy 2022 8:10
  12. Since 2015, the Committee of International Communication for Academic Research of the Japanese Society for Dialysis Therapy has held a symposium every year at the society’s Annual Congress to discuss the curre...

    Authors: Toru Hyodo, Nobuhito Hirawa, Yoshitaka Isaka, Hidetomo Nakamoto, Pichthida Thim, Elin Phon, Chanseila Hy, Sovandy Chan, Kenichi Kokubo, Hirokazu Matsubara, Haruki Wakai, Akihiro C. Yamashita and Hideki Kawanishi
    Citation: Renal Replacement Therapy 2022 8:9
  13. Patients on hemodialysis (HD) face a high mortality risk from coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and they are therefore prioritized for...

    Authors: Mineaki Kitamura, Takahiro Takazono, Kazuko Yamamoto, Takashi Harada, Satoshi Funakoshi, Hiroshi Mukae and Tomoya Nishino
    Citation: Renal Replacement Therapy 2022 8:8
  14. Renal replacement therapy (RRT) is used to manage critically ill patients with severe acute kidney injury (AKI-D), and it is undoubtedly life-sustaining for most patients. However, the prolonged unnecessary us...

    Authors: Helmut Schiffl
    Citation: Renal Replacement Therapy 2022 8:7
  15. Oral disease may be increased in people with end-stage renal disease and associated with inflammation, cardiovascular disease, and mortality. Moreover, oral disease may be essential to decide the prognosis of ...

    Authors: Takeyuki Hiramatsu, Shota Okumura, Daiki Iguchi and Hiroshi Kojima
    Citation: Renal Replacement Therapy 2022 8:6
  16. Aortic arch calcification (AAC) is a well-known risk factor for death in patients on hemodialysis (HD); however, the causes of death among them have not been well studied. The study aimed to investigate the di...

    Authors: Toyohiro Hashiba, Mototsugu Tanaka, Tomoko Honda, Satoru Kishi, Yoshiyasu Ogura, Yuto Takenaka, Satoshi Furuse, Kyosuke Nishio, Kazunobu Masaki, Tatsuya Kano and Naobumi Mise
    Citation: Renal Replacement Therapy 2022 8:5
  17. Assisted peritoneal dialysis (asPD) is a modality intended for not self-sufficient patients, mainly elderly, who are not able to perform peritoneal dialysis (PD) alone and require some help to manage the treat...

    Authors: Anna Giuliani, Luca Sgarabotto, Sabrina Milan Manani, Ilaria Tantillo, Claudio Ronco and Monica Zanella
    Citation: Renal Replacement Therapy 2022 8:2
  18. Hemodialysis (HD) is a protein catabolic event. However, the amino acid (AA) kinetics during HD sessions involved in protein breakdown have not been well investigated in patients with and without diabetes mell...

    Authors: Masako Fujiwara, Itiro Ando, You Shishido, Yutaka Imai and Hiroyuki Terawaki
    Citation: Renal Replacement Therapy 2022 8:1
  19. All-cause mortality can be reduced in patients receiving European-style high-volume post-dilution online hemodiafiltration (post-OHDF) compared with hemodialysis (HD). Japanese-style high-volume pre-dilution o...

    Authors: Kazuyoshi Okada, Hiroyuki Michiwaki, Manabu Tashiro, Tomoko Inoue, Hisato Shima, Jun Minakuchi and Shu Kawashima
    Citation: Renal Replacement Therapy 2021 7:70
  20. End-of-life medical care for patients receiving maintenance hemodialysis (HD) therapy has become an increasingly important issue worldwide. Thus far, no clear indicators and/or biomarkers exist regarding the t...

    Authors: Tadashi Yoshida, Kohkichi Morimoto, Takashin Nakayama, Takuto Torimitsu, Shotaro Kosugi, Takuma Oshida, Nobuko Yamaguchi and Mototsugu Oya
    Citation: Renal Replacement Therapy 2021 7:69
  21. Although not indicated in the USA, edoxaban tosylate hydrate 15 mg is used for venous thromboembolism (VTE) prophylaxis after orthopedic surgery of the lower extremities in Japan. However, its efficacy and saf...

    Authors: Teruhisa Kinoshita, Sayuri Otsuka, Shota Torii, Yoko Tsugeno, Shiori Fukaya, Mari Sobue, Ayumi Ishihara, Takashi Sakakibara and Norio Takimoto
    Citation: Renal Replacement Therapy 2021 7:68
  22. Peripheral artery disease (PAD) is a serious complication in hemodialysis (HD) patients. Low skin perfusion pressure (SPP) is a useful marker for detecting PAD. Malnutrition is an important cause of intractabl...

    Authors: Maho Watanabe, Asami Fuji, Sayuri Tokushima, Keiko Uemoto, Masayo Ueno, Yuko Shimomura, Kenji Ito, Tetsuhiko Yasuno, Kosuke Masutani and Takao Saito
    Citation: Renal Replacement Therapy 2021 7:67
  23. Hyperkalemia is a serious medical condition that requires immediate intervention. However, pseudohyperkalemia and reverse pseudohyperkalemia are misleading clinical manifestations that can result in incorrect ...

    Authors: Muneera Alabdulqader, Hanaa Al Alawyat, Mohammed F. Kasem, Abdelfattah Ibrahim and Abdelwahab Omara
    Citation: Renal Replacement Therapy 2021 7:66
  24. The prevalence of end-stage renal disease (ESRD) is on the rise worldwide. Meanwhile, the number of older people requiring dialysis therapy is increasing as a result of this population. We found that starting ...

    Authors: Atthaphong Phongphithakchai, Phongsak Dandecha, Sukit Raksasuk and Thatsaphan Srithongkul
    Citation: Renal Replacement Therapy 2021 7:65
  25. Peritoneal dialysis (PD)-associated peritonitis caused by Sphingomonas paucimobilis (S. paucimobilis) is very rare, and most of the characteristics of such cases are still unknown.

    Authors: Chiharu Kinoshita, Koichi Matsuda, Yumiko Kawai, Takayuki Hagiwara and Akane Okada
    Citation: Renal Replacement Therapy 2021 7:64
  26. Hemodialysis (HD) patients are at a high risk of falls and fractures. The amount of physical activity (PA) they perform may be limited by psychosomatic factors associated with fear of falling, leading to frail...

    Authors: Nobuyuki Shirai, Suguru Yamamoto, Yutaka Osawa, Atsuhiro Tsubaki, Shinichiro Morishita, Sumiyo Nitami and Ichiei Narita
    Citation: Renal Replacement Therapy 2021 7:63
  27. Hemodialysis is a medical technology implemented for various renal diseases and has a significant budget impact in Japan. Hemodialysis also affects health-related quality of life, as it interferes with daily l...

    Authors: Shinichi Noto, Masashi Miyazaki, Hidemi Takeuchi and Shinya Saito
    Citation: Renal Replacement Therapy 2021 7:62
  28. The appropriate dosing of imipenem for critically ill AKI patients undergoing CRRT remains scarce.

    Authors: Dhakrit Rungkitwattanakul, Taniya Charoensareerat, Pathakorn Kerdnimith, Nutsinee Kosumwisaisakul, Piyakamol Teeranaew, Apinya Boonpeng, Sutthiporn Pattharachayakul, Nattachai Srisawat and Weerachai Chaijamorn
    Citation: Renal Replacement Therapy 2021 7:61
  29. Removal of anti-blood group antibodies is important for successful ABO-incompatible kidney transplantation (ABOi-KTx). Double-filtration plasmapheresis (DFPP) using albumin solution removes antibodies effectiv...

    Authors: Daiki Iwami, Takenao Matsumoto, Kota Ono, Kiyohiko Hotta, Minoru Ota, Yuki Chiba, Hajime Sasaki, Takayuki Hirose, Haruka Higuchi, Yusuke Takada, Naoya Iwahara, Sachiyo Murai and Nobuo Shinohara
    Citation: Renal Replacement Therapy 2021 7:60
  30. The Japanese Association of Dialysis Physicians, the Japanese Society for Dialysis Therapy, and the Japanese Society of Nephrology jointly established COVID-19 Task Force Committee and began surveying the numb...

    Authors: Kan Kikuchi, Masaomi Nangaku, Munekazu Ryuzaki, Tomoyuki Yamakawa, Oota Yoshihiro, Norio Hanafusa, Ken Sakai, Yoshihiko Kanno, Ryoichi Ando, Toshio Shinoda, Hidetomo Nakamoto and Tadao Akizawa
    Citation: Renal Replacement Therapy 2021 7:59
  31. Enhanced oxidative stress is involved with fatigue in hemodialysis (HD) patients. Molecular hydrogen (H2) could improve the redox status. Thus, the study examines whether HD solution rendered by electrolyzed wate...

    Authors: Yoshihiro Tsujimoto, Daisuke Kuratsune, Shigeru Kabayama, Mariko Miyazaki, Yasuyoshi Watanabe, Yoshiki Nishizawa and Masaaki Nakayama
    Citation: Renal Replacement Therapy 2021 7:58
  32. Though treatment of anemia in chronic kidney disease (CKD) patients has been improved remarkably by erythropoiesis-stimulating agents (ESA), hypo-responsiveness to ESA poses a persistent problem in a subgroup ...

    Authors: Akira Ishimitsu, Hiroshi Satonaka, Masahito Furuichi, Yoshiki Murayama, Akihiro Tojo and Toshihiko Ishimitsu
    Citation: Renal Replacement Therapy 2021 7:57
  33. In Japan, forgoing life-sustaining treatment to respect the will of patients at the terminal stage is not stipulated by law. According to the Guidelines for the Decision-Making Process in Terminal-Stage Health...

    Authors: Kazuyoshi Okada, Ken Tsuchiya, Ken Sakai, Takahiro Kuragano, Akiko Uchida, Kazuhiko Tsuruya, Tadashi Tomo, Chieko Hamada, Masafumi Fukagawa, Yoshindo Kawaguchi, Yuzo Watanabe, Kaoruko Aita, Yoshitatsu Ogawa, Junji Uchino, Hirokazu Okada, Yutaka Koda…
    Citation: Renal Replacement Therapy 2021 7:56
  34. The prevalence of chronic kidney disease (CKD) has been on the rise worldwide. Epidemiological studies performed primarily in Central America and South Asia have reported high prevalence of CKD among young and...

    Authors: Kei Nagai
    Citation: Renal Replacement Therapy 2021 7:55
  35. Kidney transplantation has established itself as the most appropriate mode of renal replacement therapy for the majority with end-stage kidney disease. Although at present this is applicable for children as we...

    Authors: Thilina Gunawardena, Hemant Sharma, Ajay Kumar Sharma and Sanjay Mehra
    Citation: Renal Replacement Therapy 2021 7:54
  36. Cambodia detected its first case of COVID-19 just 3 days before WHO declared that the outbreak constituted as PHEIC. As of February 15, 2021, and after two major outbreaks, only 479 cases had been reported, 39...

    Authors: Tam Nov, Toru Hyodo, Yukie Kitajima, Kenichi Kokubo, Toshihide Naganuma, Haruki Wakai, Akihiro Yamashita, Elin Phon and Hideki Kawanishi
    Citation: Renal Replacement Therapy 2021 7:53
  37. Systemic capillary leak syndrome (SCLS) is a rare disorder characterized by hypotension, hemoconcentration, and hypoalbuminemia associated with increased capillary endothelium permeability. Patients with a chr...

    Authors: Keisuke Sunohara, Rie Shimizu, Kazushi Yasuda, Akiko Owaki, Hiroshi Nagaya, Tomohiro Kajiguchi and Shinichiro Inaba
    Citation: Renal Replacement Therapy 2021 7:52
  38. Evidence concerning online hemodiafiltration (ol-HDF) includes increased uremic toxin removal, prevention of dialysis-related hypotension, improved survival, and recovery of dialysis-related uncertain symptoms...

    Authors: Hideki Kawanishi
    Citation: Renal Replacement Therapy 2021 7:51
  39. Salazosulfapyridine is a generally safe drug often used to treat rheumatoid arthritis and ulcerative colitis. However, agranulocytosis is a rare but serious adverse effect of this drug. To date, there have bee...

    Authors: Takeshi Iida, Kimihiko Nakata, Masayoshi Fukui and Masaru Umeda
    Citation: Renal Replacement Therapy 2021 7:50
  40. In Japan, only less than 3% of patients undergoing maintenance dialysis select peritoneal dialysis (PD) as the mode of renal replacement therapy. Half of patients undergoing PD use a cycler for automated PD (A...

    Authors: Hisako Yoshida and Kazuhiko Tsuruya
    Citation: Renal Replacement Therapy 2021 7:49
  41. Whether progressive mild to moderate aortic stenosis in hemodialysis patients influences their prognosis has not been elucidated. This prospective cohort study explored whether progressive aortic stenosis pred...

    Authors: Yoriko Horiguchi, Kaoru Uemura, Naoyoshi Aoyama, Shinichi Nakajima, Tomoki Asai, Sachiko Motohashi, Manae Harada, Maoko Ida and Atsushi Yoshida
    Citation: Renal Replacement Therapy 2021 7:48
  42. Sepsis is associated with life-threatening organ dysfunction caused by a dysregulated host response to infection. However, no specific therapy has been shown to improve mortality in patients with sepsis. We co...

    Authors: Kasumi Satoh, Kyoko Nomura, Hajime Nakae, Daisuke Kudo, Shigeki Kushimoto, Masatsugu Hasegawa, Fumihito Ito, Satoshi Yamanouchi, Hiroyuki Honda, Kohkichi Andoh, Hajime Furukawa, Yasuo Yamada, Yuta Tsujimoto and Manabu Okuyama
    Citation: Renal Replacement Therapy 2021 7:47
  43. This article is a duplicated publication from the Japanese version of “2019 JSDT Guidelines for Peritoneal Dialysis” with permission from the Japanese Society for Dialysis Therapy (JSDT). This clinical practic...

    Authors: Munekazu Ryuzaki, Yasuhiko Ito, Hidetomo Nakamoto, Yuichi Ishikawa, Noritomo Itami, Minoru Ito, Atsushi Ueda, Yoshie Kanazawa, Hideki Kawanishi, Yoshihiko Kanno, Hitoshi Sugiyama, Kazuhiko Tsuruya, Hiroyuki Terawaki, Tadashi Tomo, Mizuya Fukasawa, Akihiro C. Yamashita…
    Citation: Renal Replacement Therapy 2021 7:46
  44. Vitamin D deficiency is often observed in patients undergoing maintenance hemodialysis and is associated with significantly increased risk of overall mortality. Despite reports of poor nutrition/intake, vitami...

    Authors: Keisuke Yoshida, Tomoki Yonaha, Masayuki Yamanouchi, Hirofumi Sumi, Yasuhiro Taki, Yuhei Otobe, Minoru Miyashita, Rina Hachisuka, Wei Han, Yugo Shibagaki and Naoto Tominaga
    Citation: Renal Replacement Therapy 2021 7:45
  45. Whether uric acid (UA)-lowering therapy (ULT) is effective in reducing the progression of renal dysfunction in patients with chronic kidney disease (CKD) remains controversial. Since several advances have been...

    Authors: Yukio Maruyama, Takanori Kumagai, Naoki Sugano, Shigetaka Yoshida, Kimiyoshi Ichida and Shunya Uchida
    Citation: Renal Replacement Therapy 2021 7:44
  46. In May and June 2020, an outbreak of methanol poisoning arose in the southwest United States linked to ingestion of contaminated hand sanitizer imported during the coronavirus disease 2019 pandemic, ultimately...

    Authors: Alisa C. Illescas, Christos P. Argyropoulos, Sara A. Combs, Saeed K. Shaffi, Zhi Q. Xu, Michael A. Aragon and J. Pedro Teixeira
    Citation: Renal Replacement Therapy 2021 7:43
  47. According to the annual survey of the Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) conducted at the end of 2018, there were a total of 339,841 patients receiving dialysis (hereinafter, dial...

    Authors: Kosaku Nitta, Shigeru Nakai, Ikuto Masakane, Norio Hanafusa, Shunsuke Goto, Masatomo Taniguchi, Takeshi Hasegawa, Atsushi Wada, Takayuki Hamano, Junichi Hoshino, Nobuhiko Joki, Keichi Yamamoto, Kenichiro Miura, Masanori Abe and Hidetomo Nakamoto
    Citation: Renal Replacement Therapy 2021 7:41

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