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  1. Severe pregabalin intoxication may cause serious symptoms, such as coma. Since pregabalin is a small molecule with no protein binding sites and has low volume of distribution, hemodialysis can be effective in ...

    Authors: Takashi Shimazui, Nobuya Kitamura, Kuniyuki Kako, Shinya Iwase, Toshinao Suzuki, Shota Hoshino, Hiromi Futagami, Kazuhiko Kibayashi and Ken-ichiro Nakao
    Citation: Renal Replacement Therapy 2022 8:60
  2. Chronic kidney disease (CKD) is frequently associated with renal anemia. Erythropoiesis-stimulating agent-hyporesponsive anemia is often caused by iron deficiency in patients with CKD. We hypothesized that hig...

    Authors: Takuya Yoshida, Masayuki Tsujimoto, Sachiyo Kawakami, Haruno Fujioka, Yuko Irie, Saki Nakatani, Ayako Iso, Ayaka Sugiyama, Mizuho Miyake, Kazumi Hirato, Rie Tanaka, Tomoko Oda, Taku Furukubo, Satoshi Izumi, Tomoyuki Yamakawa, Tetsuya Minegaki…
    Citation: Renal Replacement Therapy 2022 8:59
  3. The Japan Society for Blood Purification in Critical Care (JSBPCC) has reported survey results on blood purification therapy (BPT) for critically ill patients in 2005, 2009, and 2013. To clarify the current cl...

    Authors: Masanori Abe, Hidetoshi Shiga, Hiroomi Tatsumi, Yoshihiro Endo, Yoshihiko Kikuchi, Yasushi Suzuki, Kent Doi, Taka-Aki Nakada, Hiroyuki Nagafuchi, Noriyuki Hattori, Nobuyuki Hirohashi, Takeshi Moriguchi, Osamu Yamaga and Osamu Nishida
    Citation: Renal Replacement Therapy 2022 8:58
  4. Patients undergoing dialysis experience substantial decreases in muscle mass and functional muscle weakness. Muscle mass loss in patients undergoing hemodialysis is an independent predictor of survival, so mus...

    Authors: Yumi Seto, Mina Kimura, Tomohito Matsunaga, Eishi Miyasita and Yoshihiko Kanno
    Citation: Renal Replacement Therapy 2022 8:57
  5. The state of vascular access affects the efficiency of hemodialysis. Poor blood flow of vascular access causes recirculation, which reduces treatment efficiency. In the clinical setting, the resistance index (...

    Authors: Katsuyuki Umei, Naohiro Toda, Juri Izumi, Yuriko Umeda, Mari Iwata, Kazuhide Nakanishi and Toshiyuki Komiya
    Citation: Renal Replacement Therapy 2022 8:56
  6. In the Japanese guidelines on combination peritoneal dialysis (PD) and hemodialysis (HD) therapy, patients with serum beta 2 microglobulin (β2MG) levels less than 30 mg/L are recommended. And PD patients with ...

    Authors: Shinobu Moriya, Shun Nishizawa, Yayoi Tsuchihashi, Yoshihiro Inoue, Kimio Watanabe, Yugo Ito, Hassu Kin and Masaaki Nakayama
    Citation: Renal Replacement Therapy 2022 8:55
  7. The present status of Cambodia, Myanmar, Laos, Vietnam, Mongolia, and Bhutan as of June 2019 was reviewed from the interviews of leading doctors in every country. The timing was until just 6 months before the ...

    Authors: Toru Hyodo, Akihiro C. Yamashita, Nobuhito Hirawa, Yoshitaka Isaka, Hidetomo Nakamoto and Takashi Shigematsu
    Citation: Renal Replacement Therapy 2022 8:54
  8. In end-stage chronic kidney disease (CKD), patients experience disabilities stemming from organ failure. These can be worsened by symptoms and complications of underlying cause(s), and the conditions associate...

    Authors: Alfred Wai Ping Seng and Shuen-Loong Tham
    Citation: Renal Replacement Therapy 2022 8:53
  9. All-cause mortality is lower with a high substitution volume in predilution (pre) and postdilution (post) online hemodiafiltration (OHDF) than with hemodialysis (HD), and mortality does not significantly diffe...

    Authors: Kazuyoshi Okada, Manabu Tashiro, Hiroyuki Michiwaki, Tomoko Inoue, Hisato Shima, Jun Minakuchi and Shu Kawashima
    Citation: Renal Replacement Therapy 2022 8:52
  10. We compared amino acid leakage among high-volume pre-dilution on-line hemodiafiltration (Pre O-HDF), hemodialysis (HD), and post-dilution on-line hemodiafiltration (Post O-HDF).

    Authors: Motoko Kato, Shunichiro Urabe, Shohei Matsuzawa, Akira Kato, Momoko Fukazawa, Emi Hiyama, Asami Kurii, Noriko Mikami, Yukie Kitajima, Miho Hida, Kenichi Kokubo and Toru Hyodo
    Citation: Renal Replacement Therapy 2022 8:51
  11. Generalized pustular psoriasis (GPP) usually presents with fever, generalized flushing, and multiple sterile pustules on the skin, which histopathologically form subcorneal pustules characterized by Kogoj spon...

    Authors: Keiki Shimada, Daisuke Katagiri, Aika Kato, Naoto Nunose, Motohiko Sato, Yuri Katayama, Kanako Terakawa, Takahito Niikura, Emi Sakamoto, Yuki Yoshizaki, Minami Suzuki, Takashi Fukaya, Takeshi Tamaki and Hideki Takano
    Citation: Renal Replacement Therapy 2022 8:50
  12. We experienced a nosocomial outbreak of coronavirus disease 2019 (COVID-19) from November 2020 to February 2021, during the third wave of the pandemic in Japan.

    Authors: Jun Ino, Fumika Iemura, Chihiro Nakajima, Mio Kodama, Saeko Kumon, Keitaro Sato, Hitoshi Eizumi, Nobuhiro Hijikata, Sadayuki Oshio, Shingo Tachibana, Kosaku Nitta and Junichi Hoshino
    Citation: Renal Replacement Therapy 2022 8:47
  13. Antiretroviral therapy (ART) has reduced mortality caused by AIDS resulting from HIV infection. Meanwhile, the prevalence of chronic kidney disease, a chronic HIV complication, is increasing. Antiretroviral th...

    Authors: Tetsuya Abe, Daisuke Ishii, Yuki Imura, Ayano Noguchi, Kazuki Kitajima, Yasuo Takeuchi, Tatsuhiko Wada and Kazunari Yoshida
    Citation: Renal Replacement Therapy 2022 8:46
  14. In patients with severe coronavirus disease (COVID-19), the use of acrylonitrile hemofilters can reduce cytokine concentrations. However, acrylonitrile hemofilters can easily coagulate, and the effect of hemof...

    Authors: Kanako Takahashi, Hiroyuki Inoue, Masumi Kishimoto, Ryuichi Nakayama, Takehiko Kasai, Naofumi Bunya, Keisuke Harada, Shuji Uemura and Eichi Narimatsu
    Citation: Renal Replacement Therapy 2022 8:45
  15. A fluid commonly used for dialysis in Japan is prepared from two dialysate concentrates and dialysis water. Silicon (Si) from tap water is reported in dialysis water as suspended insoluble particulate matters....

    Authors: Motoyuki Imai, Masahito Yamamoto, Konomi Togo and Akihiro C. Yamashita
    Citation: Renal Replacement Therapy 2022 8:44
  16. The number of dialysis patients with diabetes is currently increasing in Japan and a similar proportion worldwide. It was suggested that approximately 20% of these patients had hypoglycemia after dialysis sess...

    Authors: Akinori Hayashi, Kenta Matoba, Yasuhiro Ohata, Naoya Shimizu, Agena Suzuki, Satoe Fujii, Marie Sato, Koji Takano and Masayoshi Shichiri
    Citation: Renal Replacement Therapy 2022 8:43
  17. The rise in end stage kidney disease (ESKD) prevalence globally calls for a need to deliver quality and cost-effective dialysis. While most are familiar with centre-based haemodialysis (HD), there is a move to...

    Authors: Yue Tein Irene Ang, Shien Wen Sheryl Gan, Chee Hsiang Liow, Chee Chin Phang, Hui Lin Lina Choong and Peiyun Liu
    Citation: Renal Replacement Therapy 2022 8:42
  18. Standard amino acid solutions have recently been removed from the contraindications for use in dialysis patients in Japan. However, the details of their safety and efficacy in these patients are still not know...

    Authors: Ryota Yasukawa, Michihiro Hosojima, Hideyuki Kabasawa, Aya Takeyama, Daisuke Ugamura, Yoshiki Suzuki, Akihiko Saito and Ichiei Narita
    Citation: Renal Replacement Therapy 2022 8:41
  19. Patient activation in chronic kidney disease (CKD) is increasingly being prioritized and considered a quality metric in CKD. Given the importance of patients’ activation in improving the quality of chronic dis...

    Authors: Reyhane Mirmazhari, Mansour Ghafourifard and Zahra Sheikhalipour
    Citation: Renal Replacement Therapy 2022 8:40
  20. Dialysis patients are predisposed to severe disease and have a high mortality rate in coronavirus disease 2019 (COVID-19) due to their comorbidities and immunocompromised conditions. Therefore, dialysis patien...

    Authors: Ayumi Yoshifuji, Masataro Toda, Munekazu Ryuzaki, Kan Kikuchi, Toru Kawai, Ken Sakai, Emi Oyama, Masayoshi Koinuma, Kazuhiko Katayama, Yuki Uehara, Norio Ohmagari, Yoshihiko Kanno, Hirofumi Kon, Toshio Shinoda, Yaoko Takano, Junko Tanaka…
    Citation: Renal Replacement Therapy 2022 8:39
  21. Peritoneal dialysis (PD) is the recommended renal replacement therapy for patients with end-stage kidney disease. Complementary hemodialysis (HD) once per week for PD patients can aid in achieving adequate dia...

    Authors: Hiroaki Io, Junichiro Nakata, Hiroyuki Inoshita, Toshiki Kano, Masanori Ishizaka, Masahiro Muto, Yu Sasaki, Takuya Maeda, Haruna Fukuzaki, Yuki Shimizu and Yusuke Suzuki
    Citation: Renal Replacement Therapy 2022 8:38
  22. Clotting within the membrane and/or venous ‘air trap’ chamber is common problems during continuous blood purification therapy. Frequent clotting during continuous blood purification therapy leads to inadequate...

    Authors: Kozue Kobayashi, Yoshitaka Kurihara, Shunichi Ueki, Kenichi Kokubo, Masaru Kubota and Hirosuke Kobayashi
    Citation: Renal Replacement Therapy 2022 8:37
  23. Accurately identifying the factors contributing to decline in activities of daily living (ADL) is important for preventing such decline in patients undergoing hemodialysis (HD). We studied the prevalence and n...

    Authors: Yusuke Matsunaga, Hiroki Takahashi, Yuta Suzuki, Shohei Yamamoto, Keigo Imamura, Shun Yoshikoshi, Juri Uchida, Takuya Nakajima, Narumi Fukuzaki, Manae Harada, Ryota Matsuzawa, Atsushi Yoshida, Kanako Ichikura, Yuko Fukase, Norio Murayama, Hanako Murase…
    Citation: Renal Replacement Therapy 2022 8:36
  24. Person-centered care (PCC) is considered an important component of high-quality care in hemodialysis units. Hemodialysis patients and nurses may have different perceptions of person-centeredness in hemodialysi...

    Authors: Simin Abdolsattari, Mansour Ghafourifard and Kobra Parvan
    Citation: Renal Replacement Therapy 2022 8:35
  25. To prevent tunnel infection of indwelling catheters, impregnation with antiseptics or antibiotics is effective. However, 13 patients using chlorhexidine–silver sulfadiazine-impregnated catheters experienced se...

    Authors: Koji Umeda, Masaji Tachikawa, Yoshinao Azuma and Tsutomu Furuzono
    Citation: Renal Replacement Therapy 2022 8:34
  26. Reportedly, dialysis solutions containing molecular hydrogen (H2) might ameliorate patient-reported fatigue in hemodialysis (HD) patients. However, it is unknown whether its impact might differ with different ...

    Authors: Susumu Uemura, Yoshitaka Kegasa, Keigo Tada, Taichi Tsukahara, Shigeru Kabayama, Tae Yamamoto, Mariko Miyazaki, Joji Takada and Masaaki Nakayama
    Citation: Renal Replacement Therapy 2022 8:32
  27. Biomarkers are needed to diagnose kidney rejection in transplant recipients. We evaluated whether dipeptidyl peptidase-4 (DPP-4) could serve as a biomarker of rejection.

    Authors: Atsushi Yamagishi, Hayato Nishida, Hiromi Ito, Hiroki Fukuhara and Norihiko Tsuchiya
    Citation: Renal Replacement Therapy 2022 8:31
  28. To assess the association between the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with all-cause mortality in Peruvian patients with chronic kidney disease (CKD) attending a ter...

    Authors: Gianfranco Eddú Umeres-Francia, María Valentina Rojas-Fernández, Percy Herrera-Añazco and Vicente Aleixandre Benites-Zapata
    Citation: Renal Replacement Therapy 2022 8:30
  29. Fungal peritonitis is a common and serious complication associated with peritoneal dialysis (PD), and it is often refractory to treatment.

    Authors: Satoshi Nishioka, Masahito Yamanaka, Yasushi Kunisho, Yuhei Aoki, Masato Higasitani, Tomoko Yokoyama, Tomoyo Oyama, Misako Ohkusu, Katuhiko Kamei and Tadashi Sofue
    Citation: Renal Replacement Therapy 2022 8:29
  30. Intravenous administration of amino acid (AA) formulation (IVAA) as intradialytic parenteral nutrition is widely used for malnourished patients with end-stage kidney disease (ESKD) treated with hemodialysis (H...

    Authors: Masako Fujiwara, Itiro Ando, You Shishido, Yutaka Imai and Hiroyuki Terawaki
    Citation: Renal Replacement Therapy 2022 8:28
  31. Dulaglutide is a once-weekly glucagon-like peptide-1 (GLP-1) receptor agonist approved for the treatment of type 2 diabetes mellitus (T2DM). However, the efficacy and safety of dulaglutide remain unclear in in...

    Authors: Daisuke Ugamura, Michihiro Hosojima, Hideyuki Kabasawa, Naohito Tanabe, Yuta Yoshizawa, Yoshiki Suzuki, Akihiko Saito and Ichiei Narita
    Citation: Renal Replacement Therapy 2022 8:26
  32. Global warming may reduce food production and force people to adopt dietary habits of inadequate quantity or quality. Such dietary habits could trigger chronic kidney disease through inappropriate nutrition or...

    Authors: Kei Nagai, Shiho Kosaka, Yuka Kawate and Norihiro Itsubo
    Citation: Renal Replacement Therapy 2022 8:25
  33. Since 2012, Senegal has conducted a national program to cover renal therapy (dialysis) expenses in public hospitals and social security-approved centers. Given the increasing demand for dialysis, national guid...

    Authors: Fatoumata Mbagnick Faye and Martine Audibert
    Citation: Renal Replacement Therapy 2022 8:24
  34. Obturator hernia (OH) is an extremely rare abdominal wall hernia with risk factors including aging, female sex, emaciation, and increased abdominal pressure. Its symptoms are nonspecific, and diagnosis is ofte...

    Authors: Kosei Yamaguchi, Mineaki Kitamura, Junichiroh Hashiguchi, Takashi Harada, Satoshi Funakoshi, Susumu Eguchi, Hiroshi Mukae and Tomoya Nishino
    Citation: Renal Replacement Therapy 2022 8:23
  35. We experienced that some hemodialysis (HD) patients with coronavirus disease 2019 (COVID-19) exacerbated hypoxemia during HD. Though HD-induced hypoxemia has been reported, there have been no reports of HD-ind...

    Authors: Masataro Toda, Ayumi Yoshifuji, Kentaro Fujii, Motoaki Komatsu, Ai Kato, Ikue Tamura, Wataru Sugi and Munekazu Ryuzaki
    Citation: Renal Replacement Therapy 2022 8:22
  36. Identification of the pathogenesis of peritoneal dialysis (PD)-related peritonitis is important. However, identification of endogenous peritonitis, especially hematogenous infection, is difficult, and there ar...

    Authors: Kento Fukumitsu, Hideaki Oka, Takaki Iwamoto, Mika Kondo, Yutaro Hirashima, Taro Kamimura, Toshiaki Nakano and Takanari Kitazono
    Citation: Renal Replacement Therapy 2022 8:21
  37. Hypokalemia is common in patients with malnutrition undergoing hemodialysis and is often involved in the development of lethal arrhythmia. Moreover, hemodialysis therapy decreases the serum potassium concentra...

    Authors: Takayuki Uchida, Susumu Ookawara, Kiyonori Ito, Hitomi Okada, Hideyuki Hayasaka, Masaya Kofuji, Masahiko Kimura, Yuichiro Ueda, Tadashi Hasebe, Naoki Momose and Yoshiyuki Morishita
    Citation: Renal Replacement Therapy 2022 8:20
  38. Although recently strengthened immunosuppression protocols have decreased the incidence of clinical acute rejection of renal transplants, subclinical acute rejection and borderline changes remain problematic. ...

    Authors: Kei Sakurabayashi, Masaki Muramatsu, Yoshihiro Itabashi, Hideyo Oguchi, Takeshi Kawamura, Yuko Hamasaki, Tetsuo Mikami, Naobumi Tochigi, Seiichiro Shishido and Ken Sakai
    Citation: Renal Replacement Therapy 2022 8:19
  39. Patients with coronavirus disease 2019 (COVID-19) who receive dialysis therapy develop more severe disease and have a poorer prognosis than patients who do not. Although various data on the treatment of patien...

    Authors: Ayumi Yoshifuji, Munekazu Ryuzaki, Yuki Uehara, Norio Ohmagari, Toru Kawai, Yoshihiko Kanno, Kan Kikuchi, Hiroshi Kon, Ken Sakai, Toshio Shinoda, Yaoko Takano, Junko Tanaka, Kazuhiko Hora, Yasushi Nakazawa, Naoki Hasegawa, Norio Hanafusa…
    Citation: Renal Replacement Therapy 2022 8:18
  40. Acute pericarditis causes acute inflammation of the pericardium. Although most cases of pericarditis are idiopathic with no identifiable cause, its etiology can be infectious, such as viral, bacterial, mycotic...

    Authors: Masahiro Egawa, Shungo Fujii, Kentaro Takase, Ryuichi Yoshimura, Asuka Yamauchi, Kaori Yoshikane, Kazuaki Tanabe, Hiroaki Shiina and Takafumi Ito
    Citation: Renal Replacement Therapy 2022 8:17
  41. Management of presenteeism in the context of chronic kidney disease (CKD) is essential for disease management, ensuring the workforce’s availability, and reducing health-related costs. The purpose of this case...

    Authors: Aki Tabata, Hiroki Yabe, Takehide Katogi, Tomoya Yamaguchi, Yuya Mitake, Tomohiro Shirai and Takayuki Fujii
    Citation: Renal Replacement Therapy 2022 8:16
  42. Although atypical hemolytic uremic syndrome (aHUS) is a life-threatening clinical entity that was characterized by thrombotic microangiopathy (TMA) with the activation of the complement system and the efficien...

    Authors: Noriaki Kawano, Tomohiro Abe, Naoko Ikeda, Yuri Nagahiro, Sayaka Kawano, Taro Tochigi, Takashi Nakaike, Kiyoshi Yamashita, Keisuke Kubo, Atsushi Yamanaka, Sohshi Terasaka, Kousuke Marutsuka, Koichi Mashiba, Ikuo Kikuchi, Kazuya Shimoda, Masanori Matsumoto…
    Citation: Renal Replacement Therapy 2022 8:15
  43. The mortality rate of novel coronaviral disease (COVID-19) patients undergoing dialysis is considerably higher than that of patients with normal kidney function. As of August 2021, only remdesivir has been app...

    Authors: Jun Ito, Moritsugu Kimura, Tomoyuki Toya, Konomi Isozumi, Atsuro Kawaji, Yudai Isozaki and Masafumi Fukagawa
    Citation: Renal Replacement Therapy 2022 8:14
  44. Currently, it is unclear whether the progression of chronic kidney disease (CKD) could be an independent predictor of antibody response after administration of a COVID-19 vaccine. This study aimed to investiga...

    Authors: Masatoshi Matsunami, Tomo Suzuki, Junko Fukuda, Toshiki Terao, Kohei Ukai, Shinnosuke Sugihara, Takumi Toishi, Kanako Nagaoka, Mayumi Nakata, Mamiko Ohara, Jun Yashima, Hiroshi Kuji and Kosei Matsue
    Citation: Renal Replacement Therapy 2022 8:13
  45. We previously reported the nutritional advantage of polymethylmethacrylate (PMMA) membranes to prevent the progression of malnutrition in dialysis patients. In this study, we examined whether a new PMMA dialyz...

    Authors: Tetsuro Chida, Hiroyuki Igarashi and Ikuto Masakane
    Citation: Renal Replacement Therapy 2022 8:11

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