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Fig. 6 | Renal Replacement Therapy

Fig. 6

From: Linagliptin inhibits lipopolysaccharide-stimulated interleukin-6 production, intranuclear p65 expression, and p38 mitogen-activated protein kinase phosphorylation in human umbilical vein endothelial cells

Fig. 6

Effects of linagliptin on indoxyl sulfate (IS)-induced interleukin (IL)-6 production. Human umbilical vein endothelial cells (HUVECs) were treated with IS and/or linagliptin. IL-6 levels in the supernatants were determined by ELISA after 5 h of treatment. **P < 0.01 vs. control; ## P < 0.01 vs. IS 1 μg/mL. Lina linagliptin

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