Fig. 6

Effects of linagliptin on indoxyl sulfate (IS)-induced interleukin (IL)-6 production. Human umbilical vein endothelial cells (HUVECs) were treated with IS and/or linagliptin. IL-6 levels in the supernatants were determined by ELISA after 5 h of treatment. **P < 0.01 vs. control; ## P < 0.01 vs. IS 1 μg/mL. Lina linagliptin