Serial changes in %MCVm after head-up tilt test in patients treated with L-DOPS. The serial changes in %MCVm during the 5-min head-up tilt test, before and after 4-week L-DOPS treatment at each period are shown. L-DOPS improves %MCVm decrement throughout the 5-min head-up tilt test. Data are mean ± SEM. *P < 0.05 vs. before L-DOPS. Abbreviations: %MCVm percentage of the change in the mean middle cerebral artery flow velocity, L-DOPS
l-threo-3,4-dihydroxyphenylserine. From Fujisaki et al.