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Table 2 IVGTT before and after DPP-4i treatment (n = 10)

From: The dipeptidyl peptidase-4 inhibitor may improve the insulin secretion in type 2 diabetes patients just after starting hemodialysis treatment: preliminary study

 

Before

After

P value

Fasting plasma glucose (mg/dl)

117 ± 22

107 ± 16

0.33

Pre-HD plasma glucose (mg/dl)

182 ± 15

145 ± 17

0.035

Glu(0) mg/dl

174 ± 20

150 ± 27

0.023

Glu(5)

228 ± 32

204 ± 37

0.065

Glu(15)

202 ± 27

182 ± 43

0.09

IRI(0) μU/ml

13.0 ± 5.8

15.4 ± 11.1

0.37

IRI(5)

14.6 ± 6.9

23.4 ± 16.6

0.038

IRI(15)

15.7 ± 7.8

19.6 ± 14.6

0.258

5′ΔIRI

1.61 ± 1.87

8.04 ± 8.07

0.015

15′ΔIRI

2.63 ± 2.75

4.24 ± 4.64

0.268

0.268

6.4 ± 2.9

5.7 ± 2.9

0.408

CPR(5)

6.1 ± 2.4

6.1 ± 2.8

0.976

CPR(15)

6.1 ± 2.4

6.1 ± 2.8

0.918

GLP-1 pmol/L

2.64 ± 0.76

6.63 ± 4.42

0.012