Table 2 Comparison of stool and serum parameters of hemodialysis patients before and 1, 2, and 3 months after treatment with lubiprostone
From: Lubiprostone, a novel laxative, might improve hyperphosphatemia without water dilution
Parameter | Before treatment | Month 1 | Month 2 | Month 3 | |||
|---|---|---|---|---|---|---|---|
Mean ± SD | Mean ± SD | p value | Mean ± SD | p value | Mean ± SD | p value | |
Stool frequency (times/month) | 1.8 ± 1.3 | 4.3 ± 1.8 | p < 0.001 | 4.9 ± 1.9 | p < 0.001 | 4.5 ± 1.5 | p < 0.001 |
Bristol Stool Form Scale | 2.3 ± 1.0 | 3.4 ± 0.7 | p < 0.001 | 3.5 ± 0.8 | p < 0.001 | 3.6 ± 0.6 | p < 0.001 |
Serum Na (mEq/L) | 137.3 ± 3.3 | 137.5 ± 3.0 | p = 0.963 | 138.2 ± 3.5 | p = 0.070 | 138.2 ± 4.0 | p = 0.180 |
Serum Cl (mEq/L) | 102.6 ± 4.0 | 103.0 ± 3.0 | p = 0.434 | 103.1 ± 3.6 | p = 0.504 | 103.0 ± 3.2 | p = 0.743 |
Serum K (mEq/L) | 4.4 ± 0.7 | 4.4 ± 0.7 | p = 0.873 | 4.3 ± 0.6 | p = 0.415 | 4.3 ± 0.6 | p = 0.626 |
Serum Ca (mg/dL) | 9.2 ± 0.6 | 9.1 ± 0.6 | p = 0.159 | 9.2 ± 0.6 | p = 0.608 | 9.2 ± 0.6 | p = 0.499 |
Serum IP (mg/dL) | 4.7 ± 1.5 | 4.5 ± 1.6 | p = 0.123 | 4.0 ± 1.3 | p < 0.001 | 3.8 ± 1.1 | p < 0.001 |
Geriatric nutritional risk index | 85.6 ± 12.8 | 85.4 ± 11.9 | p = 0.501 | 86.2 ± 11.9 | p = 0.220 | 86.4 ± 11.1 | p = 0.061 |