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Table 2 Comparison of stool and serum parameters of hemodialysis patients before and 1, 2, and 3 months after treatment with lubiprostone

From: Lubiprostone, a novel laxative, might improve hyperphosphatemia without water dilution

Parameter Before treatment Month 1 Month 2 Month 3
Mean ± SD Mean ± SD p value Mean ± SD p value Mean ± SD p value
Stool frequency (times/month) 1.8 ± 1.3 4.3 ± 1.8 p < 0.001 4.9 ± 1.9 p < 0.001 4.5 ± 1.5 p < 0.001
Bristol Stool Form Scale 2.3 ± 1.0 3.4 ± 0.7 p < 0.001 3.5 ± 0.8 p < 0.001 3.6 ± 0.6 p < 0.001
Serum Na (mEq/L) 137.3 ± 3.3 137.5 ± 3.0 p = 0.963 138.2 ± 3.5 p = 0.070 138.2 ± 4.0 p = 0.180
Serum Cl (mEq/L) 102.6 ± 4.0 103.0 ± 3.0 p = 0.434 103.1 ± 3.6 p = 0.504 103.0 ± 3.2 p = 0.743
Serum K (mEq/L) 4.4 ± 0.7 4.4 ± 0.7 p = 0.873 4.3 ± 0.6 p = 0.415 4.3 ± 0.6 p = 0.626
Serum Ca (mg/dL) 9.2 ± 0.6 9.1 ± 0.6 p = 0.159 9.2 ± 0.6 p = 0.608 9.2 ± 0.6 p = 0.499
Serum IP (mg/dL) 4.7 ± 1.5 4.5 ± 1.6 p = 0.123 4.0 ± 1.3 p < 0.001 3.8 ± 1.1 p < 0.001
Geriatric nutritional risk index 85.6 ± 12.8 85.4 ± 11.9 p = 0.501 86.2 ± 11.9 p = 0.220 86.4 ± 11.1 p = 0.061
  1. SE standard deviation, Na sodium, Cl chloride, K potassium, Ca calcium, IP inorganic phosphorus