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Table 2 Characteristics of patients with and without early VA failure

From: Factors associated with early failure of vascular access in acute-phase patients

Parameter

Without failure (n = 382)

With failure (n = 53)

P value

Age (years)

66.9 ± 14.6

70.7 ± 15.6

0.0819

Male (%)

65.2

49.1

0.0225*

Diabetes (%)

45.0

52.8

0.2854

Hypertension (%)

68.3

62.3

0.3770

Atrial fibrillation (%)

8.3

15.1

0.1128

Primary cause of admission

 Exacerbation of CRF (%)

64.1

54.7

0.1832

 Heart disease (%)

13.6

17.0

0.5081

 Heart failure (%)

9.9

15.1

0.2535

 Coronary artery disease (%)

2.4

1.9

0.8309

 Infectious disease (%)

6.5

9.4

0.4366

 Malignancy (%)

3.4

3.8

0.8898

 Cephalopathy (%)

2.6

3.8

0.6302

 Cerebral infarction (%)

0.5

1.9

0.2611

 Intracranial hemorrhage (%)

1.0

0.0

0.4542

 Peripheral artery disease (%)

0.5

1.9

0.2611

 Aortic disease (%)

1.0

0.0

0.4542

 Others (%)

8.1

9.4

0.7440

Warfarin (%)

9.7

11.3

0.7086

Antiplatelet agent (%)

31.2

32.1

0.8919

Statin (%)

32.2

30.2

0.7687

ACEi or ARB (%)

46.9

41.5

0.4642

Beta blocker (%)

34.0

34.0

0.9921

CCB (%)

60.0

60.4

0.9523

LVEF (%)

55.6 ± 12.9

56.5 ± 12.7

0.7022

SBP (mmHg)

138.6 ± 24.2

132.1 ± 23.7

0.0671

DBP (mmHg)

75.1 ± 16.2

69.1 ± 17.3

0.0119*

WBC (103/μL)

7.2 ± 3.2

8.0 ± 3.5

0.0870

Hb (g/dL)

9.8 ± 1.7

9.7 ± 1.9

0.6712

PLT (104/μL)

19.2 ± 7.8

19.7 ± 8.3

0.6834

TP (g/dL)

6.1 ± 0.9

5.9 ± 1.0

0.1570

ALB (g/dL)

3.0 ± 0.6

2.7 ± 0.8

0.0002**

BUN (mg/dL)

68.5 ± 28.7

63.0 ± 34.2

0.2035

Cr (mg/dL)

7.3 ± 3.0

6.4 ± 2.4

0.0414*

eGFR (mL/min/1.7 m2)

7.3 ± 3.9

7.6 ± 3.6

0.6209

AST (IU/L)

23.2 ± 20.0

25.8 ± 24.9

0.3891

ALT (IU/L)

18.9 ± 21.3

17.7 ± 21.4

0.7076

CRP (mg/dL)

2.2 ± 3.3

3.2 ± 4.4

0.0390*

APTT

30.2 ± 9.7

31.2 ± 8.1

0.5918

PT-INR

1.16 ± 0.40

1.16 ± 0.20

0.9994

AVF (%)

77.5

66.0

0.0671

  1. VA vascular access, CRF chronic renal failure, ACEi angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker, LVEF left ventricular ejection fraction, SBP systolic blood pressure, DBP diastolic blood pressure, WBC white blood cell, Hb hemoglobin, PLT platelet, TP total protein, ALB albumin, BUN blood urea nitrogen, Cr creatinine, eGFR estimated glomerular filtration rate, AST aspartate aminotransferase, ALT alanine transaminase, CRP C-reactive protein, APTT activated partial thromboplastin time, PT-INR international normalized ratio of prothrombin time, AVF, arteriovenous fistula
  2. *P < 0.05; **P < 0.01