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Table 4 Trends in relative and standardized standard deviations of all clinical indices by age group

From: Heterogeneity of clinical indices among the older dialysis population—a study on Japanese dialysis population

Age groups 15–29 30–44 45–59 60–74 75–89 90+ Trend analysis
  Relative CV p value Relative CV p value Relative CV p value Relative CV p value Relative CV p value Relative CV p value Chi-square values p value
Corrected calcium (mg/dl) 1.069 0.001 1.008 0.134 1 Ref 0.967 <0.001 0.937 <0.001 0.922 <0.001 356.9 <0.001
Phosphate (mg/dl) 1.058 0.006 1.073 <0.001 1 Ref 0.987 0.000 1.041 <0.001 1.105 <0.001 463.8 <0.001
Total cholesterol (mg/dl) 0.993 0.396 0.986 0.038 1 Ref 1.007 0.042 1.007 0.073 1.013 0.160 11.3 0.080
Non-HDL (mg/dl) 0.984 0.299 1.002 0.405 1 Ref 0.993 0.057 0.975 <0.001 0.964 0.008 32.9 <0.001
HDL cholesterol (mg/dl) 0.829 <0.001 0.983 0.021 1 Ref 0.958 <0.001 0.909 <0.001 0.868 <0.001 482.4 <0.001
%creatinine generation rate (%) 0.988 0.347 0.950 <0.001 1 Ref 1.099 <0.001 1.254 <0.001 1.446 <0.001 3282.4 <0.001
Normalized protein catabolic rate (g/kg/day) 0.990 0.370 0.968 <0.001 1 Ref 1.023 <0.001 1.024 <0.001 1.111 <0.001 122.8 <0.001
Albumin (g/dl) 1.126 <0.001 0.999 0.448 1 Ref 1.092 <0.001 1.233 <0.001 1.331 <0.001 3463.1 <0.001
Body height (cm) 1.399 <0.001 1.079 <0.001 1 Ref 0.999 0.401 1.052 <0.001 1.130 <0.001 693.7 <0.001
Postdialytic body weight (kg) 1.167 <0.001 1.172 <0.001 1 Ref 0.847 <0.001 0.825 <0.001 0.808 <0.001 5473.5 <0.001
Body mass index (kg/m2) 1.053 0.013 1.146 <0.001 1 Ref 0.841 <0.001 0.803 <0.001 0.848 <0.001 5456.5 <0.001
Body weight reduction (kg) 1.133 <0.001 1.026 0.001 1 Ref 0.968 <0.001 1.026 <0.001 1.137 <0.001 401.1 <0.001
Fractional body weight reduction (%) 1.029 0.155 1.009 0.123 1 Ref 1.041 <0.001 1.123 <0.001 1.228 <0.001 884.0 <0.001
Session duration (h) 1.071 0.001 1.079 <0.001 1 Ref 0.917 <0.001 0.975 <0.001 1.077 <0.001 1243.2 <0.001
spKt/V 1.010 0.367 1.032 <0.001 1 Ref 0.917 <0.001 0.961 <0.001 1.014 0.160 604.6 <0.001
eqKt/V 1.024 0.207 1.071 <0.001 1 Ref 0.950 <0.001 0.964 <0.001 1.069 <0.001 410.3 <0.001
Blood flow rate (ml/min) 1.098 <0.001 1.034 <0.001 1 Ref 0.970 <0.001 1.003 0.239 1.058 <0.001 243.6 <0.001
Predialytic blood urea (mg/dl) 0.989 0.364 0.986 0.044 1 Ref 1.037 <0.001 1.102 <0.001 1.161 <0.001 620.9 <0.001
Creatinine (mg/dl) 1.032 0.130 0.954 <0.001 1 Ref 1.074 <0.001 1.185 <0.001 1.326 <0.001 1992.9 <0.001
Systolic blood pressure (torr) 0.976 0.164 1.040 <0.001 1 Ref 0.998 0.342 1.034 <0.001 1.095 <0.001 184.0 <0.001
Diastolic blood pressure (torr) 1.126 <0.001 1.061 <0.001 1 Ref 1.036 <0.001 1.102 <0.001 1.186 <0.001 692.0 <0.001
Pulse rate (/min) 1.032 0.100 0.992 0.139 1 Ref 1.045 <0.001 1.089 <0.001 1.095 <0.001 449.3 <0.001
Hemoglobin (g/dl) 1.042 0.035 1.003 0.315 1 Ref 0.998 0.289 1.040 <0.001 1.038 0.001 185.3 <0.001
Glycoalbumin (%) 1.186 0.089 1.171 <0.001 1 Ref 0.877 <0.001 0.826 <0.001 0.887 <0.001 703.6 <0.001
A1c (%) 1.182 0.054 1.128 <0.001 1 Ref 0.899 <0.001 0.868 <0.001 0.842 <0.001 564.6 <0.001
  1. Indicated CVs were relative (i.e., SD of the 45–59 years age group was set as 1) CV. The p values for each age group were calculated from F tests compared with those of the 45 and 59 years age group. Trend analysis was performed using Bartlett’s test; chi-square and p values are shown. HDL high-density lipoproteins, spKt/V single pool Kt/V, eqKt/V equilibrated Kt/V, HbA1c hemoglobin A1c, n number of patients, SD standard deviation, ref reference