Table 1 Baseline characteristics of patients treated with CHDF
From: Effect of continuous hemodiafiltration using an AN69ST membrane in patients with sepsis
Parameter | AN69ST (n = 32) | PMMA (n = 17) | P value |
|---|---|---|---|
Male (%) | 71.9 | 88.2 | 0.1914 |
Age (years) | 71.1 ± 11.4 | 74.7 ± 9.4 | 0.1123 |
Height (cm) | 159.8 ± 8.9 | 160.7 ± 9.2 | 0.7845 |
BMI | 22.4 ± 4.7 | 21.6 ± 3.8 | 0.4371 |
Cause of sepsis | |||
Peritonitis (%) | 46.9 | 64.7 | 0.2339 |
UTI (%) | 6.3 | 11.8 | 0.5022 |
Pneumoniae (%) | 15.6 | 11.8 | 0.7132 |
Infection bacteria | |||
Gram-positive coccus (%) | 40.6 | 41.2 | 0.9702 |
Gram-negative rod (%) | 34.4 | 47.1 | 0.3857 |
Unknown (%) | 31.3 | 23.5 | 0.5691 |
Past history | |||
Diabetes (%) | 21.9 | 23.5 | 0.8949 |
Hypertension (%) | 53.1 | 35.3 | 0.2339 |
Maintenance dialysis (%) | 12.5 | 29.4 | 0.1456 |
Ventilator (%) | 84.4 | 94.1 | 0.3220 |
Surgical treatment (%) | 50.0 | 76.5 | 0.0727 |
SBP (mmHg) | 105.2 ± 26.8 | 107.9 ± 21.7 | 0.4945 |
DBP (mmHg) | 54.3 ± 13.2 | 57.6 ± 15.7 | 0.5012 |
MBP (mmHg) | 71.3 ± 15.9 | 74.3 ± 16.6 | 0.5777 |
HR (bpm) | 99.1 ± 22.0 | 99.8 ± 17.2 | 0.9828 |
BT (°C) | 37.3 ± 1.0 | 36.9 ± 1.1 | 0.0740 |
CAI | 38.5 ± 27.3 | 28.4 ± 19.2 | 0.1689 |
DOA (μg/kg/min) | 0.00 ± 0.00 | 0.55 ± 2.28 | 0.1573 |
DOB (μg/kg/min) | 0.89 ± 2.00 | 0.55 ± 2.28 | 0.1918 |
NA (μg/kg/min) | 0.38 ± 0.26 | 0.27 ± 0.19 | 0.1472 |
WBC (1000/μL) | 15.4 ± 9.5 | 11.8 ± 11.0 | 0.1035 |
Hb (g/dL) | 10.6 ± 2.1 | 10.3 ± 1.4 | 0.4749 |
Plt (10,000/μL) | 14.5 ± 10.8 | 13.6 ± 7.4 | 0.8091 |
ALB (g/dL) | 2.0 ± 0.5 | 1.9 ± 0.5 | 0.6591 |
AST (IU/L) | 310.1 ± 754.4 | 285.7 ± 999.8 | 0.2610 |
ALT (IU/L) | 172.2 ± 440.3 | 118.2 ± 388.2 | 0.1753 |
UN (mg/dL) | 57.2 ± 24.3 | 48.0 ± 26.1 | 0.1252 |
Cr (mg/dL) | 3.6 ± 2.2 | 3.9 ± 3.6 | 0.4067 |
eGFR (ml/min/1.7 m2) | 19.0 ± 12.9 | 25.8 ± 19.0 | 0.4127 |
Na (mEq/L) | 138.2 ± 4.1 | 137.8 ± 6.3 | 0.2291 |
K (mEq/L) | 4.5 ± 1.0 | 4.3 ± 0.8 | 0.3714 |
cCa (mg/dL) | 9.4 ± 0.9 | 9.4 ± 0.9 | 0.8058 |
P (mg/dL) | 4.6 ± 1.7 | 4.7 ± 1.9 | 0.8148 |
Mg (mg/dL) | 2.0 ± 0.5 | 1.8 ± 0.3 | 0.3516 |
CRP (mg/dL) | 20.4 ± 12.5 | 14.8 ± 12.2 | 0.0991 |
HCO3 − (mEq/L) | 16.9 ± 5.6 | 17.0 ± 4.3 | 0.8500 |
Lactate (mg/dL) | 40.4 ± 32.3 | 23.9 ± 15.3 | 0.0928 |
APACHE 2 | 32.1 ± 7.0 | 32.5 ± 4.8 | 0.8086 |
APACHE2 without kidney | 29.3 ± 7.1 | 30.2 ± 4.9 | 0.7120 |
SOFA | 13.1 ± 2.7 | 11.9 ± 2.7 | 0.0807 |
SOFA without kidney | 10.4 ± 2.3 | 9.5 ± 2.8 | 0.4709 |
PMX (%) | 25.0 | 58.8 | 0.0194* |
CRRT (days) | 4.4 ± 2.9 | 5.3 ± 4.9 | 0.8970 |
Death at 28 days (%) | 43.8 | 35.3 | 0.1625 |
Cr at 28 days (mg/dL) | 1.4 ± 1.3 (n = 14) | 2.5 ± 1.9 (n = 9) | 0.0777 |