Table 1 Patients’ baseline profiles (N = 40)
| Â | Saxagliptin | Mitiglinide | P value |
|---|---|---|---|
Number | 20 | 20 | |
Female (n) | 2 | 5 | 0.4075 |
Age | 68.6 ± 10.1 | 63.0 ± 13.1 | 0.1288 |
BMI | 22.5 ± 2.7 | 24.2 ± 3.5 | 0.0973 |
HD dulation (months) | 42.8 ± 36.3 | 70.4 ± 58.2 | 0.0745 |
DM dulation (years) | 14.5 ± 6.2 | 15.7 ± 7.4 | 0.5853 |
Acarbose (mg/day) | 225.0 ± 82.2 | 187.5 ± 69.4 | 0.3728 |
Voglibose (mg/day) | 0.75 ± 0.16 | 0.66 ± 0.13 | 0.3527 |
Mitiglinide (mg/day) | 16.9 ± 5.3 | 15.0 ± 0.0 | 0.4082 |
Glimepiride (mg/day) | – | 0.50 ± 0.0 | – |
HbA1c (%) | 6.0 ± 0.9 | 6.3 ± 1.4 | 0.5219 |
GA (%) | 19.2 ± 3.2 | 18.9 ± 4.4 | 0.8372 |
BUN (mg/dL) | 59.7 ± 11.9 | 64.4 ± 14.6 | 0.2724 |
Cr (mg/dL) | 9.36 ± 2.63 | 10.81 ± 3.47 | 0.1396 |
UA (mg/dL) | 5.8 ± 1.4 | 6.5 ± 1.5 | 0.1427 |
Na (mEq/L) | 133.9 ± 2.2 | 138.4 ± 2.7 | 0.384 |
K (mEq/L) | 5.0 ± 0.7 | 4.7 ± 0.7 | 0.1736 |
Cl (mEq/L) | 107.3 ± 3.3 | 95.0 ± 3.2 | 0.0898 |
Ca (mg/dL) | 8.2 ± 0.4 | 8.6 ± 0.7 | 0.0285 |
P (mg/dL) | 5.1 ± 1.0 | 5.4 ± 1.1 | 0.246 |
TP (g/dL) | 6.8 ± 0.5 | 6.7 ± 0.4 | 0.5831 |
Glu (mg/dL) | 163.0 ± 59.8 | 158.2 ± 55.9 | 0.7934 |
AST (U/L) | 13.9 ± 6.1 | 11.5 ± 5.2 | 0.2023 |
ALT (U/L) | 10.3 ± 5.4 | 9.8 ± 4.6 | 0.7818 |
LDH (U/L) | 208.4 ± 45.8 | 179.7 ± 44.3 | 0.0515 |
ALP (U/L) | 238.5 ± 68.2 | 256.3 ± 146.5 | 0.6199 |
GTP (U/L) | 34.5 ± 78.2 | 23.3 ± 14.1 | 0.5437 |
iPTH (pg/mL) | 191.0 ± 101.3 | 204.2 ± 151.0 | 0.7457 |