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Table 2 Baseline characteristics of the early and late CRRT groups

From: The optimal timing of continuous renal replacement therapy according to the modified RIFLE classification in critically ill patients with acute kidney injury: a retrospective observational study

 

All patients

Early patients

Late patients

P value

(n = 189)

(n = 52)

(n = 137)

 

Baseline data

 Age (years), median (IQR)

72 (61–78)

74 (62–78)

71 (61–77)

0.37

 Gender (male), n (%)

133 (70)

36 (69)

97 (71)

0.86

 Baseline serum creatinine (mg/dl), median (IQR)

1.0 (0.7–1.5)a

1.5 (0.9–2.9)a

0.9 (0.7–1.2)a

<0.001

Comorbidities

 Hypertension, n (%)

116 (61)

36 (69)

80 (58)

0.19

 Diabetes mellitus, n (%)

56 (30)

17 (33)

39 (29)

0.6

 Chronic kidney disease, n (%)

89 (47)

33 (63)

56 (41)

0.009

  Stage 2, n (%)

6 (7)

2 (4)

4 (3)

0.69

  Stage 3, n (%)

36 (40)

10 (19)

26 (19)

1

  Stage 4, n (%)

16 (18)

10 (19)

6 (4)

0.002

  Stage 5, n (%)

12 (13)

10 (19)

2 (2)

<0.001

  Unknown, n (%)

19 (21)

1(2)

18(16)

0.04

 Congestive heart failure, n (%)

34 (18)

10 (19)

24 (18)

0.83

Data on admission to ICU

 Serum creatinine (mg/dl), median (IQR)

2.0 (1.2–3.4)

1.5 (1.1–2.9)

2.1 (1.3–3.5)

0.047

 Bilirubin (mg/dl), median (IQR)

0.8 (0.5–1.6)

0.8 (0.5–1.3)

0.8 (0.5–1.7)

0.42

 Platelets (cells/103), median (IQR)

146 (66–211)

124 (66–207)

146 (68–214)

0.98

 PaO2/FiO2 ratio (Torr), median (IQR)

200 (117–329)

195 (117–297)

200 (119–329)

0.91

 SAPS II, median (IQR)

57 (44–72)

57 (40–68)

57 (45–72)

0.5

 Glasgow Coma Scale, median (IQR)

14 (6–15)

14 (3–15)

14 (6–15)

0.24

  1. Abbreviations: CRRT continuous renal replacement therapy, ICU intensive care unit, IQR interquartile range, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate, SAPS II Simplified Acute Physiology Score II
  2. aSixty-five, six, and fifty-nine patients with unknown baseline creatinine were not included