| Cardiovascular events | Stroke |
---|
(/1000 patients year) | (/1000 patients year) |
---|
CHOIR | 51.7 | 5.4 |
CREATE | 58 | 7.2 |
TREAT | 76.4 | 9.5 |
A21 | 15.6 | 2.1 |
Gonryo (G3–5) | 21.8 | 8.6 |
- The events defined as cardiovascular events in each study were as follows: the events specified as primary endpoints in the CHOIR, CREATE, and TREAT studies; myocardial infarction, cerebral infarction, cerebellar infarction, lung congestion, and heart failure, which were specified as adverse events, in the A21 study; angina, myocardial infarction, heart failure, and stroke in stage G3–5 patients in the Gonryo study