Skip to main content

Table 3 Interventional studies examining effects of Mg-containing phosphate binders on cardiovascular calcification/atherosclerosis

From: Cardiovascular disease, mortality, and magnesium in chronic kidney disease: growing interest in magnesium-related interventions

Authors (year) Subjects Study design Outcome Serum Mg levels in the Mg group (mg/dL) Benefits of Mg supplementation
Turgut et al. (2008) [76] 47, HD RCT with assignment to magnesium citrate or calcium acetate for 2 months Changes in carotid intima-media thickness evaluated by ultrasound Pre: 2.50 ± 0.36
Post: 2.69 ± 0.39 		Yes
Tzanakis et al. (2014) [77] 72, HD RCT with assignment to calcium acetate or calcium acetate/magnesium carbonate for 12 months Changes in arterial calcification of the femur, pelvis, hands, and abdomen evaluated by plain X-ray using vascular calcification scores Pre: 2.59 ± 0.29
Post: 2.83 ± 0.38 		Yes
  1. Abbreviations: HD hemodialysis, RCT randomized controlled trial
Back to article page

Renal Replacement Therapy

ISSN: 2059-1381

Contact us