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Fig. 4 | Renal Replacement Therapy

Fig. 4

From: Is hemodialysis itself a risk factor for dementia? An analysis of nationwide registry data of patients on maintenance hemodialysis in Japan

Fig. 4

Sensitivity analyses for the excluded patients’ influence evaluation. The sensitivity analyses were conducted to evaluate how the exclusion of patients affected the results. We analyzed the dementia risk under the assumptions that none of the excluded patients had dementia (negative analysis) and that all the excluded patients had dementia (positive analysis). These analyses were conducted using the multifactor model, which included the following factors as independent variables; hemodialysis duration, age, sex, comorbidity of diabetes, Kt/V, BMI, albumin level, CRP level, hemoglobin level, history of myocardial infarction, limb amputation, or hip fracture, ADLs, and place of residence. Please note that the X axis is a linear plot. a The target patients of the analysis were only the non-diabetic patients. b The target patients of the analysis were only the diabetic patients. Asterisk indicates the number of patients with dementia. Dagger indicates ORs for development of dementia for every 10 years of hemodialysis duration. ADLs activities of daily living, BMI body mass index, CI confidence interval, CRP C-reactive protein, OR odds ratio

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