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Table 1 Laboratory findings of the present case

From: Severe refractory TAFRO syndrome requiring continuous renal replacement therapy complicated with Trichosporon asahii infection in the lungs and myocardial infarction: an autopsy case report and literature review

Complete blood count

Blood urea nitrogen

60.7 mg/dL

 Serum M protein

Negative

 White blood cell

14,600 /μL

Creatinine

2.94 mg/dL

 Platelet-associated IgG

238.0 ng/107 cells

 Neutrophil

84.6%

C-reactive protein

14.25 mg/dL

 Anti-platelet Ab

Negative

 Lymphocyte

9.4%

β-D-glucan

<  6.0 pg/mL

 Soluble IL-2 receptor

1120 U/mL

 Monocyte

5.6%

Ferritin

419 ng/mL

 Direct Coombs test

Negative

 Basophil

0.1%

Serum iron

9 μg/dL

 Indirect Coombs test

Negative

 Eosinophil

0.0%

Total iron binding capacity

155 μg/dL

 IL-6 (serum, on day 9)

25.2 pg/mL

 Red blood cell

426 × 104 /μL

Haptoglobin

268 mg/dL

 VEGF (plasma, on day 9)

224 pg/mL

 Hemoglobin

11.7 g/dL

Thyroid stimulating hormone

6.4 μIU/ml

 IL-6 (ascites, on day 9)

3310 pg/mL

 Hematocrit

34.8%

Free T3

1.4 pg/ml

 VEGF (ascites, on day 9)

335 pg/mL

 Reticulocyte

15‰

Free T4

1.1 ng/dl

 STS

Negative

 Platelet

11.1 × 104 /μL

BNP

61 pg/mL

 HBs Ag

Negative

 IPF

10.9%

CEA

0.5 U/mL

 HBs Ab

Negatve

Coagulation test

CA19–9

5 ng/mL

 HBc Ab

Negative

 APTT

45.3 s

IgA

264 mg/dL

 HCV Ab

Negative

 PT-INR

1.30

IgG

2461 mg/dL

 HIV Ab

Negative

 Fibrinogen

479 mg/dL

IgG4

235 mg/dL

 IFN-γ release assay

Negative

Blood chemistry and immunological tests

IgM

88 mg/dL

 Helicobacter pylori IgG

Negative

 Sodium

138 mEq/L

ANA

Positive (×40)

 CMV-IgG

Positive

 Potassium

4.1 mEq/L

RF

2 U/mL

 CMV-IgM

Negative

 Chloride

101 mEq/L

CH50

44.9 U/mL

 EBV VCA-IgG Ab

Positive

 Calcium

8.1 mg/dL

C3

50 mg/dL

 EBV VCA-IgM Ab

Negative

 Total protein

6.4 g/dL

C4

14 mg/dL

 EBNA Ab

Positive

 Albumin

2.1 g/dL

Anti-ds-DNA IgG Ab

Negative

 HHV-8 DNA PCR

Negative

 Total bilirubin

0.7 mg/dL

PR3-ANCA

Negative

Bacterial cultures

 Asparate aminotransferase

28 U/L

MPO-ANCA

Negative

 Blood cultures

Negative

 Alanine aminotransferase

12 U/L

Anti-SS-A Ab

> 1200 U/mL

 Ascitic fluid cultures

Negative

 Lactate dehydrogenase

278 U/L

Anti-SS-B Ab

Negative

 Urine culture

Negative

 Alkali phosphatase

768 U/L

Anti-CL Ab

Negative

Urinalysis

 γ- glutamyltransferase

129 U/L

Anti-CLβ2GPI Ab

Negative

 Protein

(1+)

 Amylase

50 U/L

Anti-Scl-70 Ab

Negative

 Occult blood

(−)

 Creatine kinase

694 U/L

Anti-RNP Ab

Negative

 NAG

44.8 U/L

 Glucose

121 mg/dL

Anti-Sm Ab

Negative

 β2-MG

81 μg/L

 Hemoglobin A1c

5.3%

Anti-mitochondrial M2 Ab

Negative

 Granular casts

10–19 /WF

 Uric acid

15.1 mg/dL

Anti-smooth muscle Ab

Negative

 BJP

Negative

  1. β2-MG β2-microglobulin. Ab antibody, ANA antinuclear antibody, APTT activated partial thromboplastin time, BJP Bence Jones protein BNP brain natriuretic peptide, C3 complement component 3, C4 complement component 4, CA 19–9 carbohydrate antigen 19–9, CEA carcinoembryonic antigen, CH50 50% hemolytic complement activity, CL cardiolipin, CMV cytomegalovirus, ds-DNA double stranded-DNA, EBNA Epstein-Barr virus-nuclear antigen, EBV Epstein-Barr virus, GPI glycoprotein I, HBc Ab hepatitis B core antibody, HBs Ag hepatitis B surface antigen, HCV hepatitis C virus, HHV-8 human herpes virus-8, HIV human immunodeficiency virus, IFN-γ interferon-γ, Ig immunoglobulin, IL interleukin, IPF immature platelet fraction, MPO myeloperoxidase, NAG N-acetyl-β-D-glucosaminidase, PCR polymerase chain reaction, PR3-ANCA proteinase-3-anti-neutrophil cytoplasmic antibody, PT-INR prothrombin time-international normalized ratio, RF rheumatoid factor, RNP ribonucleoprotein, Scl scleroderma, Sm Smith, SS Sjögren syndrome, STS serologic test for syphilis, T3 triiodothyronine, T4 thyroxin, TSH Thyroid stimulating hormone, VEGF vascular endothelial cell growth factor, VCA viral capsid antigen, WF whole field