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Table 2 Comparison of baseline characteristics between the “not present” and “at least mild” groups

From: Usefulness of the Japanese version of the 5-D itch scale for rating pruritus experienced by patients undergoing hemodialysis

  Not present (n = 124) number (%) Mild or above (n = 212) number (%) p value
Male/female 74 (59.7)/50 (40.3) 139 (65.6)/73 (34.4) 0.280*
Median, IQR age (years) 69, 62–76 71, 63–78 0.275**
Median, IQR duration of hemodialysis (months) 72, 30–152 63, 34–123 0.301**
Primary illness of chronic kidney disease
 Diabetes mellitus 50 (40.3) 102 (48.1) 0.166*
 Chronic glomerulonephritis 38 (30.6) 49 (23.1) 0.128*
 Nephrosclerosis 12 (9.7) 23 (10.8) 0.734*
 Other 15 (12.1) 20 (9.4) 0.441*
 Unknown 9 (7.3) 18 (8.5) 0.688*
Comorbidities
 Hypertension 114 (91.9) 198 (93.4) 0.616*
 Ischemic heart disease 24 (19.4) 55 (25.9) 0.169*
 Congestive heart failure 27 (21.8) 37 (17.5) 0.330*
 Cerebral vascular disease 28 (22.6) 57 (26.9) 0.381*
 Peripheral arterial disease 15 (12.1) 24 (11.3) 0.830*
 Chronic lung disease 8 (6.5) 16 (7.5) 0.707*
 Chronic liver disease 3 (2.4) 16 (7.5) < 0.05*
 Malignant neoplasm 6 (4.8) 13 (6.1) 0.620*
Medication for pruritus
  Moisturizers 27 (21.8) 115 (54.2) < 0.001*
 Topical steroids 5 (4.0) 78 (36.8) < 0.001*
 Other topical drugs 3 (2.4) 32 (15.1) < 0.001*
 Oral antihistamines 2 (1.6) 11 (5.2) 0.143***
 Anti-allergy injections 0 (0.0) 2 (0.9) 0.533***
  Nalfurafine 10 (8.1) 29 (13.7) 0.121*
Laboratory parameters (median, IQR)
 Serum albumin (g/dL) 3.7, 3.5–3.8 3.6, 3.4–3.8 0.164**
 Serum corrected calcium (mg/dL) 8.8, 8.5–9.2 8.8, 8.4–9.2 0.949**
 Phosphorus (mg/dL) 4.9, 4.2–5.4 4.8, 3.9–5.5 0.937****
 Whole PTH (pg/mL) 63.6, 47.4–101.4 81.8, 55.0–124.9 < 0.05**
 Hemoglobin (g/dL) 11.4, 10.7–12.0 11.3, 10.8–11.9 0.557**
 β2-microglobulin (mg/L) 22.9, 19.9–25.9 23.0, 20.1–26.5 0.571**
 Kt/V 1.5, 1.4–1.6 1.5, 1.4–1.6 0.760*****
  1. Data are presented as n (%), unless stated otherwise. p values were calculated using χ2 test*, Mann-Whitney U test**, Fisher’s exact test***, Student’s t test****, and Welch’s test*****, respectively