Fig. 9
From: Current status and future aspects of kidney transplantation in Japan
Induction of nephron progenitor cells. (Left) Glomeruli and renal tubules generated in vitro from human induced pluripotent stem cells (iPSCs). The induced nephron progenitors were recombined with spinal cord feeders and cultured for 9 days. Magenta, Wt1; yellow, nephrin; green, E-cadherin. (Right) Hematoxylin-eosin staining of human iPSC-derived glomerulus vascularized upon transplantation into mice. Note the presence of red blood cells (arrowhead) in the glomerulus and eosinophilic substance in Bowman’s capsule (asterisk). Photographs were referred as figures 2 and 3 in Nishinakamura and associates [20]