Fig. 2

Rate of change in transmembrane pressure. Box plot: Center lines indicate the medians; box limits indicate the 25th and 75th percentiles; whiskers extend 1.5 times the interquartile range from the 25th and 75th percentiles. #p < 0.05 compared with 6 h. Time 6 h is the rate of change in 0–6 h. Time 12 h is the rate of change in 0–12 h. Time 24 h is the rate of change in 0–24 h. TMP transmembrane pressure