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Table 2 Examinations for differential diagnosis of primary and secondary thrombotic microangiopathy

From: A case of subacute-onset myelodysplastic syndrome with infection mimicking thrombotic thrombocytopenic purpura: a case report with literature review

Blood
 ADAMTS13 61.2% Anti-cardiolipin antibody 12 U/mL
 ADAMTS13 inhibitor < 0.5 BU/mL Lupus anticoagulant 1.2
 Anti-lipopolysaccharide antibody Negative CMV antigenemia (C10/11) Negative
 Anti-dsDNA antibody < 10 U/mL CMV IgM 0.27 (negative)
 Anti-Sm antibody < 2.0 U/mL EBV VCA IgG 40×
 Anti-SS-A antibody < 1.0 U/mL EBV VCA IgM < 10×
 Anti-SS-B antibody < 1.0 U/mL EBV EBNA 10×
 Anti-RNP antibody < 2.0 U/mL Influenza A virus < 4×
 Anti-centromere antibody < 5.0 Influenza B virus < 4×
 Anti-Scl-70 antibody < 1.0 U/mL HIV-1/HIV-2 antibodies Negative
 Anti-Jo-1 antibody < 1.0 U/mL HIV-1 p24 antigen Negative
 MPO-ANCA < 1.0 U/mL VZV IgG 28.8 (positive)
 PR3-ANCA < 1.0 U/mL VZV IgM 0.23 (negative)
 Anti-GBM antibody < 2.0 U/mL Parvovirus B19 IgM < 0.8
Feces
 Shiga toxin Negative   
  1. GBM glomerular basement membrane, CMV cytomegalovirus, EBV Epstein-Barr virus, VCA viral capsid antigen, EBNA EB nuclear antigen, VZV varicella zoster virus