Fig. 4

Time points of inotropic score over 12 h. The two groups were compared using two-way repeated measurements analysis of variance. Inotropic score was calculated as follows: (dopamine dose [μg/kg/min]) + (dobutamine dose [μg/kg/min]) + (adrenaline dose [μg/kg/min]) × 100 + (noradrenaline dose [μg/kg/min]) × 100 + phenylephrine dose [μg/kg/min]) × 100. For both groups, a paired t test was performed between 0 h and each additional time point. *P < 0.05. PMX-DHP, direct hemoperfusion therapy with polymyxin B immobilized fiber cartridge; SD, standard deviation