Fig. 5

Time points of vasopressor dependency index over 12 h. The two groups were compared using two-way repeated measurements analysis of variance. Vasopressor dependency index was calculated as follows: (inotropic score)/(mean blood pressure). For both groups, a paired t test was performed between 0 h and each additional time point. *P < 0.05. PMX-DHP: direct hemoperfusion therapy with polymyxin B immobilized fiber cartridge, SD: standard deviation